Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(101 products)
- Adiponectin receptor(5 products)
- CFTR(65 products)
- CGRP Receptor(54 products)
- Calcium Channel(541 products)
- Chloride channel(53 products)
- GABA Receptor(365 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(54 products)
- Potassium Channel(280 products)
- Proton pump(42 products)
- SGLT(31 products)
- Sodium Channel(209 products)
- TRP/TRPV Channel(95 products)
Show 13 more subcategories
Found 2512 products of "Membrane Transporter/Ion Channel"
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Tariquidar dimesylate
CAS:Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.Formula:C80H94N8O25S4Purity:98%Color and Shape:SolidMolecular weight:1695.9MASP-2-IN-1
MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.Formula:C22H21N7O3SColor and Shape:SolidMolecular weight:463.512Linoleic Acid Amide
CAS:<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Formula:C18H33NOPurity:98%Color and Shape:SolidMolecular weight:279.46PNU-140975
CAS:PNU-140975 is a bio-active chemical.Formula:C3H9N5O2Color and Shape:SolidMolecular weight:147.138(R)-IDHP
CAS:(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.Formula:C12H16O5Color and Shape:SolidMolecular weight:240.25GDC-0334
CAS:GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.Formula:C24H19F8N5O3SColor and Shape:SolidMolecular weight:609.5Caloxin 2A1 acetate
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.Formula:C66H95N19O24Purity:98.2%Color and Shape:SolidMolecular weight:1538.57LY 274614
CAS:LY 274614 is a structurally novel systemically active competitive NMDA receptor antagonist.Formula:C11H20NO5PColor and Shape:SolidMolecular weight:277.25CW2158
CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.Formula:C14H8F4N4O2Molecular weight:340.05834AZD-3161
CAS:AZD-3161 is a sodium channel regulator for pain.Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.43NT 13
CAS:<p>NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.</p>Formula:C18H30N4O7Purity:98%Color and Shape:SolidMolecular weight:414.45Furosemide sodium
CAS:<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73(R)-Funapide
CAS:(R)-Funapide ((R)-TV 45070), the less active R-enantiomer of Funapide, acts as a potent Nav1.7 sodium channel blocker, primarily utilized in pain research [1].Formula:C22H14F3NO5Color and Shape:SolidMolecular weight:429.35Migrastatin
CAS:Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinicFormula:C27H39NO7Color and Shape:SolidMolecular weight:489.609ATP synthase inhibitor 3
ATP synthase inhibitor3 (compound PT6) is an orally active inhibitor targeting the F-ATP synthase of Mycobacterium tuberculosis (IC50=0.788 μM). It effectively inhibits the growth of the Mycobacterium tuberculosis H37Rv strain (ATCC-27294) in vitro, depleting intracellular ATP levels at an IC50 of 30 μM.Formula:C33H28ClFN4O2SMolecular weight:599.12A 80915A
CAS:A80915A: Semi-naphthoquinone antibiotic, blocks gastric (H(+)-K+)-ATPase; potency varies with enzyme conformation; K+ reduces binding rate.Formula:C26H31Cl3O5Color and Shape:SolidMolecular weight:529.88Lei-Dab7 TFA
Lei-Dab7 TFA blocks SK2 channels with 3.8 nM affinity, is >200x selective, and enhances LTP in rat hippocampus.Formula:C143H237F3N46O41S6Color and Shape:SolidMolecular weight:3506.08CW8001
CW8001 is a covalent Exportin-1 (XPO1) inhibitor with an EC50 value of 1 nM for inhibiting T cell activation. It prevents the nuclear localization of NFAT transcription factors, thereby suppressing the expression of inflammatory cytokines like IL-2. CW8001 shows potential for research in T cell-driven immune diseases such as graft-versus-host disease (GVHD).Color and Shape:Odour SolidChlorpropylate
CAS:Chlorpropylate is an insecticide.Formula:C17H16Cl2O3Purity:98%Color and Shape:SolidMolecular weight:339.21KNa1.1-IN-2
CAS:KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48
