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TRP/TRPV Channel
Methyl salicylate
CAS:119-36-8
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by …
Formula:
C8H8O3
Purity:
99.13%
Color and Shape:
Colourless To Slightly Yellow Liquid
Molecular weight:
152.15
Estimated delivery in United States, on Thursday 3 Feb 2022
ML204
CAS:5465-86-1
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Formula:
C15H18N2
Purity:
99.98%
Color and Shape:
solid
Molecular weight:
226.32
Estimated delivery in United States, on Thursday 3 Feb 2022
ICILIN
CAS:36945-98-9
Icilin(AG 3-5) is a synthetic TRPM8 ion channel super-agonist.
Formula:
C16H13N3O4
Purity:
98.00%
Color and Shape:
Light Yellow Solid
Molecular weight:
311.29
Estimated delivery in United States, on Thursday 3 Feb 2022
Nonivamide
CAS:2444-46-4
Nonivamide is found in herbs and spices. Nonivamide is an alkaloid from Capsicum species Nonivamide …
Formula:
C17H27NO3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
293.4
Estimated delivery in United States, on Thursday 3 Feb 2022
HC030031
CAS:349085-38-7
HC-030031 is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s …
Formula:
C18H21N5O3
Purity:
99.90%
Color and Shape:
solid
Molecular weight:
355.39
Estimated delivery in United States, on Thursday 3 Feb 2022
RQ00203078
CAS:1254205-52-1
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
Formula:
C21H13ClF6N2O5S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
554.85
Estimated delivery in United States, on Thursday 3 Feb 2022
Probenecid
CAS:57-66-9
Probenecid is a benzoic acid derivative with antihyperuricemic property.
Formula:
C13H19NO4S
Purity:
99.95%
Color and Shape:
Crystals From Dil Alcohol Physical Description Odorless White Or Almost White Crystalline Powder Slightly Bitter
Molecular weight:
285.36
Estimated delivery in United States, on Thursday 3 Feb 2022
AMG517
CAS:659730-32-2
AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin …
Formula:
C20H13F3N4O2S
Purity:
99.85%
Color and Shape:
solid
Molecular weight:
430.4
Estimated delivery in United States, on Thursday 3 Feb 2022
SKF-96365 hydrochloride
CAS:130495-35-1
SKF-96365, a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in …
Formula:
C22H27ClN2O3
Purity:
99.48%
Color and Shape:
solid
Molecular weight:
402.91
Estimated delivery in United States, on Thursday 3 Feb 2022
Zucapsaicin
CAS:25775-90-0
Zucapsaicin is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin …
Formula:
C18H27NO3
Purity:
99.67%
Color and Shape:
solid
Molecular weight:
305.41
Estimated delivery in United States, on Thursday 3 Feb 2022
RN-1734
CAS:946387-07-1
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and …
Formula:
C14H22Cl2N2O2S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
353.31
Estimated delivery in United States, on Thursday 3 Feb 2022
Capsazepine
CAS:138977-28-3
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the …
Formula:
C19H21ClN2O2S
Purity:
98.00%
Color and Shape:
White To Off-White Powder
Molecular weight:
376.9
Estimated delivery in United States, on Thursday 3 Feb 2022
A 967079
CAS:1170613-55-4
A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 …
Formula:
C12H14FNO
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
207.24
Estimated delivery in United States, on Thursday 3 Feb 2022
JNJ-17203212
CAS:821768-06-3
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 …
Formula:
C17H15F6N5O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
419.32
Estimated delivery in United States, on Thursday 3 Feb 2022
SB705498
CAS:501951-42-4
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of …
Formula:
C17H16BrF3N4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
429.23
Estimated delivery in United States, on Thursday 3 Feb 2022
TC-I2000
CAS:1159996-20-9
TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells …
Formula:
C23H18F4N2O
Purity:
98.87%
Color and Shape:
solid
Molecular weight:
414.4
Estimated delivery in United States, on Thursday 3 Feb 2022
EIPA
CAS:1154-25-2
EIPA (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits …
Formula:
C11H18ClN7O
Purity:
98.52%
Color and Shape:
Off-White To Yellow Solid
Molecular weight:
299.76
Estimated delivery in United States, on Thursday 3 Feb 2022
BI-749327
CAS:2361241-23-6
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 …
Formula:
C23H21F3N4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
442.43
Estimated delivery in United States, on Thursday 3 Feb 2022
TRPM8 antagonist 2
CAS:259674-19-6
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 …
Formula:
C26H26N2O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
398.5
Estimated delivery in United States, on Thursday 3 Feb 2022
Pyr6
CAS:245747-08-4
Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin …
Formula:
C17H9F7N4O
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
418.27
Estimated delivery in United States, on Thursday 3 Feb 2022
AC1903
CAS:831234-13-0
AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe …
Formula:
C19H17N3O
Purity:
98.33%
Color and Shape:
Solid
Molecular weight:
303.36
Estimated delivery in United States, on Thursday 3 Feb 2022
AMG9810
CAS:545395-94-6
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) …
Formula:
C21H23NO3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
337.41
Estimated delivery in United States, on Thursday 3 Feb 2022
PF-05105679
CAS:1398583-31-7
PF-05105679 has the potential for cold-related pain. PF-05105679 is an orally active and selective TRPM8 …
Formula:
C26H21FN2O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
428.45
Estimated delivery in United States, on Thursday 3 Feb 2022
GSK1016790A
CAS:942206-85-1
GSK1016790A (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with …
Formula:
C28H32Cl2N4O6S2
Purity:
99.05%
Color and Shape:
solid
Molecular weight:
655.61
Estimated delivery in United States, on Thursday 3 Feb 2022
N-Ethyl-p-menthane-3-carboxamide
CAS:39711-79-0
N-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
Formula:
C13H25NO
Purity:
98.00%
Color and Shape:
Drypowder
Molecular weight:
211.34
Estimated delivery in United States, on Thursday 3 Feb 2022
Pyr10
CAS:1315323-00-2
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the …
Formula:
C18H13F6N3O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
449.37
Estimated delivery in United States, on Thursday 3 Feb 2022
GFB-8438
CAS:2304549-73-1
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM …
Formula:
C16H14ClF3N4O2
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
386.75
Estimated delivery in United States, on Thursday 3 Feb 2022
IA-Alkyne
CAS:930800-38-7
IA-Alkyne is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically …
Formula:
C8H12INO
Molecular weight:
265.09
Estimated delivery in United States, on Thursday 3 Feb 2022
AMG2850
CAS:1470018-52-0
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 …
Formula:
C19H17F6N3O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
417.35
Estimated delivery in United States, on Thursday 3 Feb 2022
TRPA1 Antagonist 1
CAS:1984825-08-2
TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate …
Formula:
C24H20F6N5Na2O7PS
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
713.45
Estimated delivery in United States, on Thursday 3 Feb 2022
Linoleoyl Ethanolamide
CAS:68171-52-8
Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation …
Formula:
C20H37NO2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
323.51
Estimated delivery in United States, on Thursday 3 Feb 2022
Camphor
CAS:76-22-2
Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is …
Formula:
C10H16O
Purity:
99.53%
Color and Shape:
Clear White Crystals Characteristic Odor Solid Powder
Molecular weight:
152.24
Estimated delivery in United States, on Thursday 3 Feb 2022
RN-1747
CAS:1024448-59-6
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: …
Formula:
C17H18ClN3O4S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
395.86
Estimated delivery in United States, on Thursday 3 Feb 2022
Cardamonin
CAS:19309-14-9
Cardamomin (also known as cardamonin) is a chalconoid that has been isolated from several plants …
Formula:
C16H14O4
Purity:
99.84%
Color and Shape:
solid
Molecular weight:
270.28
Estimated delivery in United States, on Thursday 3 Feb 2022
SAR7334
CAS:1333210-07-3
SAR7334 is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
Formula:
C21H22ClN3O
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
367.87
Estimated delivery in United States, on Thursday 3 Feb 2022
Methyl syringate
CAS:884-35-5
Methyl syringate has a unique inhibitory activity toward aflatoxin production with a different mode of …
Formula:
C10H12O5
Purity:
99.76%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
212.2
Estimated delivery in United States, on Thursday 3 Feb 2022
D-Camphor
CAS:464-49-3
(+)-Camphor is the oil extracted from the wood of the Camphor tree Cinnamomum Camphora with …
Formula:
C10H16O
Purity:
98.82%
Color and Shape:
Less Or White Crystals Sublimes Flash Point 149°F Burns Physical Description Colorless Or White Crystals Sublimes Flash Point 149°F Burns
Molecular weight:
152.24
Estimated delivery in United States, on Thursday 3 Feb 2022
BCTC
CAS:393514-24-4
BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 …
Formula:
C20H25ClN4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
372.89
Estimated delivery in United States, on Thursday 3 Feb 2022
GSK2798745
CAS:1419609-94-1
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: …
Formula:
C25H28N6O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
460.53
Estimated delivery in United States, on Thursday 3 Feb 2022
GSK2193874
CAS:1336960-13-4
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
Formula:
C37H38BrF3N4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
691.6
Estimated delivery in United States, on Thursday 3 Feb 2022
JYL 1421
CAS:401907-26-4
JYL 1421 is an antagonist of TRPV1 receptor (IC50: 8 nM).
Formula:
C20H26FN3O2S2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
423.57
Estimated delivery in United States, on Thursday 3 Feb 2022
GSK3395879
CAS:2215852-91-6
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: …
Formula:
C20H15F4N3O5S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
485.41
Estimated delivery in United States, on Thursday 3 Feb 2022
PF4840154
CAS:1332708-14-1
PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited …
Formula:
C26H38N6O2
Purity:
98.48%
Color and Shape:
Solid
Molecular weight:
466.63
Estimated delivery in United States, on Thursday 3 Feb 2022
M8-B Hydrochloride
CAS:883976-12-3
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
Formula:
C22H25ClN2O3S
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
432.96
Estimated delivery in United States, on Thursday 3 Feb 2022
EIPA hydrochloride
CAS:1345839-28-2
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel …
Formula:
C11H19Cl2N7O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
336.22
Estimated delivery in United States, on Thursday 3 Feb 2022
WS-12
CAS:68489-09-8
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 …
Formula:
C18H27NO2
Purity:
99.71%
Color and Shape:
Whitish To White Solid Crystalline
Molecular weight:
289.41
Estimated delivery in United States, on Thursday 3 Feb 2022
ML329
CAS:19992-50-8
ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity.
Formula:
C16H12N2O4S
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
328.34
Estimated delivery in United States, on Thursday 3 Feb 2022
TC-I 2014
CAS:1221349-53-6
TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally …
Formula:
C23H19F6N3O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
467.41
Estimated delivery in United States, on Thursday 3 Feb 2022
A 425619
CAS:581809-67-8
A 425619 is a potent TRPV1 antagonist
Formula:
C18H14F3N3O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
345.3252
Estimated delivery in United States, on Thursday 3 Feb 2022
JT010
CAS:917562-33-5
JT010 is an effective agonist of TRPA1 (EC50: 0.65 nM).
Formula:
C16H19ClN2O3S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
354.85
Estimated delivery in United States, on Thursday 3 Feb 2022
TCS 5861528
CAS:332117-28-9
TCS5861528 is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 …
Formula:
C19H23N5O3
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
369.42
Estimated delivery in United States, on Thursday 3 Feb 2022
SB366791
CAS:472981-92-3
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
Formula:
C16H14ClNO2
Purity:
99.12%
Color and Shape:
solid
Molecular weight:
287.74
Estimated delivery in United States, on Thursday 3 Feb 2022
Capsaicin
CAS:404-86-4
Capsaicin is an active component of chili peppers. It selectively binds to TRPV1 which is …
Formula:
C18H27NO3
Purity:
99.41%
Color and Shape:
Pure Dark Red Solid Solid
Molecular weight:
305.41
Estimated delivery in United States, on Thursday 3 Feb 2022
Pico145
CAS:1628287-16-0
Pico145 is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits ()-englerin A-activated TRPC4/TRPC5 channels (IC50s: …
Formula:
C23H20ClF3N4O5
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
524.88
Estimated delivery in United States, on Thursday 3 Feb 2022
N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride
CAS:1135272-09-1
N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride is an inhibitor of TRPC4.
Formula:
C16H17ClN4
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
300.786
Estimated delivery in United States, on Thursday 3 Feb 2022
ASP7663
CAS:1190217-35-6
ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.
Formula:
C14H14FNO3
Purity:
98.11%
Color and Shape:
Solid
Molecular weight:
263.26
Estimated delivery in United States, on Thursday 3 Feb 2022
M-084 hydrochloride
CAS:51314-51-3
M-084 hydrochloride is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.
Formula:
C11H15N3
Purity:
99.84%
Color and Shape:
solid
Molecular weight:
189.257
Estimated delivery in United States, on Thursday 3 Feb 2022
TRPV4 agonist-1 free base
CAS:2314467-59-7
TRPV4 agonist-1 free base is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of …
Formula:
C25H22F2N4O2
Purity:
99.86%
Molecular weight:
448.46
Estimated delivery in United States, on Thursday 3 Feb 2022
Linopirdine
CAS:105431-72-9
Linopirdine is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current …
Formula:
C26H21N3O
Purity:
99.92%
Color and Shape:
solid
Molecular weight:
391.46
Estimated delivery in United States, on Thursday 3 Feb 2022
A-1165442
CAS:1221443-94-2
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
Formula:
C22H20ClF2N3O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
431.86
Estimated delivery in United States, on Thursday 3 Feb 2022
AM12
CAS:2387510-84-9
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
Formula:
C15H9BrO5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
349.13
Estimated delivery in United States, on Thursday 3 Feb 2022
cim0216
CAS:1031496-06-6
CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of …
Formula:
C21H21N3O2
Purity:
99.60%
Molecular weight:
347.41
Estimated delivery in United States, on Thursday 3 Feb 2022
AMG-333
CAS:1416799-28-4
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the …
Formula:
C20H12F5N3O4
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
453.33
Estimated delivery in United States, on Thursday 3 Feb 2022
AM-0902
CAS:1883711-97-4
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
Formula:
C17H15ClN6O2
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
370.79
Estimated delivery in United States, on Thursday 3 Feb 2022
Optovin
CAS:348575-88-2
Optovin is a TRPA1 activator, which is reversibly photoactivated.
Formula:
C15H13N3OS2
Purity:
99.16%
Color and Shape:
solid
Molecular weight:
315.41
Estimated delivery in United States, on Thursday 3 Feb 2022
Vanilloid receptor antagonist 1
CAS:871814-52-7
Vanilloid receptor antagonist 1 is a potent vanilloid receptor TRPV1 antagonist.
Formula:
C18H15N3O2
Purity:
98.77%
Molecular weight:
305.33
Estimated delivery in United States, on Thursday 3 Feb 2022
HC067047 Hydrochloride(883031-03-6 free base)
CAS:1481646-76-7
HC-067047 hydrochloride is a potent and selective TRPV4 antagonist. HC-067047 hydrochloride reversibly inhibited currents through …
Formula:
C26H29ClF3N3O2
Molecular weight:
507.98
Estimated delivery in United States, on Thursday 3 Feb 2022
TRPM4-IN-1
CAS:351424-20-9
TRPM4-IN-1 is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
Formula:
C15H11Cl2NO4
Purity:
98.75%
Molecular weight:
340.16
Estimated delivery in United States, on Thursday 3 Feb 2022
Hydroxy--sanshool
CAS:83883-10-7
Hydroxy--sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent …
Formula:
C16H25NO2
Purity:
99.47%
Color and Shape:
solid
Molecular weight:
263.37
Estimated delivery in United States, on Thursday 3 Feb 2022
HC067047
CAS:883031-03-6
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4-PDH …
Formula:
C26H28F3N3O2
Purity:
99.45%
Color and Shape:
solid
Molecular weight:
471.51
Estimated delivery in United States, on Thursday 3 Feb 2022
Dihydromorin
CAS:18422-83-8
trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma …
Formula:
C15H12O7
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
304.3
Estimated delivery in United States, on Thursday 3 Feb 2022
