Proton pump
Proton pumps are membrane proteins that actively transport protons (H+) across the cell membrane or organelle membranes, creating a proton gradient that is essential for various cellular processes. The most well-known proton pump is the H+/K+ ATPase, found in the stomach lining, which is responsible for acid secretion. Proton pumps are also critical in cellular respiration and pH regulation. Dysregulation of proton pump activity is associated with conditions such as acid reflux, ulcers, and metabolic acidosis. At CymitQuimica, we provide a selection of proton pump inhibitors and modulators to support your research in gastroenterology, metabolism, and cellular bioenergetics.
Found 42 products of "Proton pump"
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Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:White SolidMolecular weight:345.42Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormula:C16H14F3N3O2SPurity:99.18% - 99.84%Color and Shape:White Crystalline PowderMolecular weight:369.36Zinc pyrithione
CAS:Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.Formula:C10H8N2O2S2ZnPurity:99.09% - 99.70%Color and Shape:Off-White To Tan PowderMolecular weight:317.71EN6
CAS:EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Formula:C19H14F2N4O2Purity:95.74% - 97.04%Color and Shape:SolidMolecular weight:368.34Ref: TM-T11191
1mg44.00€1mL*10mM (DMSO)66.00€5mg84.00€10mg130.00€25mg195.00€50mg250.00€100mg379.00€500mg862.00€Pantoprazole Sodium Hydrate
CAS:Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormula:C16H14F2N3NaO4SH2OPurity:98.32%Color and Shape:SolidMolecular weight:432.37Corza6
Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).Formula:C203H293N55O61S7Color and Shape:SolidMolecular weight:4704.29Caloxin 2A1 acetate
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.Formula:C66H95N19O24Purity:98.2%Color and Shape:SolidMolecular weight:1538.57Corza6 TFA
Corza6 TFA is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage-sensor domain (VSD) loop of hHv1 with a dissociation constant (Kd) of approximately 1 nM under the native hyperpolarized resting membrane potential (RMP) of mammalian cells. Additionally, Corza6 TFA induces sperm capacitation and enables continuous reactive oxygen species (ROS) production in white blood cells (WBC).Color and Shape:Odour SolidEsomeprazole sodium-d6
CAS:Esomeprazole sodium-d6 is a deuterated compound of Esomeprazole sodium.Formula:C17H12D6N3NaO3SMolecular weight:373.44(R)-Lansoprazole
CAS:(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitorFormula:C16H14F3N3O2SPurity:98.09% - 98.99%Color and Shape:Brown SolidMolecular weight:369.36Esomeprazole Magnesium trihydrate
CAS:Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophagealFormula:C34H42MgN6O9S2Purity:98.52%Color and Shape:Off-White PowderMolecular weight:767.17Thonzonium Bromide
CAS:Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).
Formula:C32H55BrN4OPurity:98.48% - 99.94%Color and Shape:SolidMolecular weight:591.71Rabeprazole Sulfide
CAS:Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.Formula:C18H21N3O2SPurity:99.34% - 99.78%Color and Shape:Off-White Crystalline PowderMolecular weight:343.44Vonoprazan
CAS:Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer andFormula:C17H16FN3O2SPurity:99.87% - 99.92%Color and Shape:SolidMolecular weight:345.39Esomeprazole Sodium
CAS:Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Formula:C17H18N3O3S·NaPurity:98.17% - >99.99%Color and Shape:SolidMolecular weight:367.4Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purity:95.87% - 99.36%Color and Shape:SolidMolecular weight:622.83Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purity:98.91% - 99.71%Color and Shape:SolidMolecular weight:956.68Ref: TM-TQ0184
1mg66.00€5mg145.00€10mg203.00€1mL*10mM (DMSO)215.00€25mg409.00€50mg595.00€100mg833.00€Ilaprazole sodium
CAS:Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.
Formula:C19H17N4NaO2SPurity:99.06%Color and Shape:SolidMolecular weight:388.42Esomeprazole Magnesium
CAS:Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Formula:C34H36MgN6O6S2Purity:98.76% - 99.73%Color and Shape:SolidMolecular weight:713.12Abscisic Acid
CAS:Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.Formula:C15H20O4Purity:99.52% - 99.73%Color and Shape:White PowderMolecular weight:264.32Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35Ilaprazole
CAS:Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.Formula:C19H18N4O2SPurity:99.91%Color and Shape:SolidMolecular weight:366.44Tenatoprazole
CAS:Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).Formula:C16H18N4O3SPurity:99.57%Color and Shape:White Crystalline PowderMolecular weight:346.4Esomeprazole
CAS:Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.Formula:C17H19N3O3SPurity:97.3%Color and Shape:SolidMolecular weight:345.42Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Formula:C18H20N3NaO3SPurity:98% - 99.91%Color and Shape:White Or Off White Crystalline PowderMolecular weight:381.42Tegoprazan
CAS:Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.Formula:C20H19F2N3O3Purity:98.22%Color and Shape:SolidMolecular weight:387.38Ref: TM-T17030
1mg50.00€5mg114.00€1mL*10mM (DMSO)126.00€10mg170.00€25mg281.00€50mg371.00€100mg485.00€200mg690.00€Vonoprazan Fumarate
CAS:Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.Formula:C21H20FN3O6SPurity:98.94% - 99.98%Color and Shape:SolidMolecular weight:461.46Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:97.16% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.37KM 91104
CAS:KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.Formula:C14H12N2O4Purity:99.04%Color and Shape:SolidMolecular weight:272.26Ref: TM-T9230
1mg84.00€5mg160.00€1mL*10mM (DMSO)221.00€10mg245.00€25mg494.00€50mg713.00€100mg982.00€500mg1,998.00€Diphyllin
CAS:Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.Formula:C21H16O7Purity:99.76% - 99.98%Color and Shape:SolidMolecular weight:380.35ATP4A Protein, Human, Recombinant (His & Myc)
ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:54.6 kDa (predicted)Ref: TM-TMPH-01892
5µg106.00€10µg171.00€20µg276.00€50µg418.00€100µg566.00€200µg875.00€500µg1,554.00€1mg2,350.00€Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.84%Color and Shape:Clear In WaterMolecular weight:367.4WY-47766
CAS:WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.Formula:C14H13N3O2SPurity:97.63% - 99.83%Color and Shape:SolidMolecular weight:287.34Saviprazole
CAS:Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.Formula:C15H10F7N3O2S2Purity:97.06% - 97.17%Color and Shape:SolidMolecular weight:461.38Abeprazan hydrochloride
CAS:Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPaseFormula:C19H18ClF3N2O3SPurity:98.57%Color and Shape:SolidMolecular weight:446.87Ilaprazole sodium hydrate
CAS:Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.Formula:C19H21N4NaO4SPurity:99.20%Color and Shape:SolidMolecular weight:424.45Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purity:99.54%Color and Shape:SolidMolecular weight:366.46Pumaprazole
CAS:Pumaprazole (BY-841) is an antagonist of a reversible proton pump.Formula:C19H22N4O2Purity:99.91%Color and Shape:SolidMolecular weight:338.4Ref: TM-T16682
1mg87.00€5mg178.00€1mL*10mM (DMSO)203.00€10mg295.00€25mg602.00€50mg964.00€100mg1,558.00€200mg2,097.00€Soraprazan
CAS:BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.Formula:C21H25N3O3Purity:97.69% - 99.84%Color and Shape:SolidMolecular weight:367.44(R)-(+)-Pantoprazole sodium
CAS:(R)-(+)-Pantoprazole ((R)-(+)-BY1023) sodium is a proton pump inhibitor used in the study of esophageal erosion and ulcers.Formula:C16H15F2N3NaO4SColor and Shape:SolidMolecular weight:406.36V-ATPase-IN-1
CAS:V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.Formula:C21H20ClNO2Color and Shape:SolidMolecular weight:353.84Zastaprazan
CAS:Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.Formula:C22H26N4OPurity:99.97%Color and Shape:SolidMolecular weight:362.48
