PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
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Ensifentrine
CAS:1884461-72-6
Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 …
Formula:
C26H31N5O4
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
477.56
Ref: TM-T25376
| 1mg | 35.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 533.00 € | ||
| 100mg | 847.00 € | ||
| 200mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Z-HA155
CAS:1312201-00-5
Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.
Formula:
C24H19BFNO5S
Purity:
98.28%
Color and Shape:
Solid
Molecular weight:
463.29
Ref: TM-T11533
| 1mg | 49.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 154.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 692.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Crisaborole
CAS:906673-24-3
Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.
Formula:
C14H10BNO3
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
251.05
Ref: TM-T4285
| 10mg | 46.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 90.00 € | ||
| 200mg | 109.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
CRT0273750
CAS:1979939-16-6
CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an …
Formula:
C25H22ClF3N4O2
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
502.92
Ref: TM-T31101
| 1mg | 35.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 339.00 € | ||
| 100mg | 509.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Nortadalafil
CAS:171596-36-4
Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and …
Formula:
C21H17N3O4
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
375.38
Ref: TM-T6147
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 567.00 € | ||
| 200mg | 805.00 € | ||
| 500mg | 1,198.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Homo Sildenafil
CAS:642928-07-2
Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.
Formula:
C23H32N6O4S
Purity:
99.88%
Color and Shape:
White Solid
Molecular weight:
488.6
Ref: TM-T8919
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 393.00 € | ||
| 200mg | 552.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
GEBR-7b
CAS:67387-76-2
GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.
Formula:
C13H16O3
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
220.26
Ref: TM-T19865
| 5mg | 34.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 169.00 € | ||
| 200mg | 246.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Enoximone
CAS:77671-31-9
Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.
Formula:
C12H12N2O2S
Purity:
95.52%
Color and Shape:
Solid
Molecular weight:
248.3
Ref: TM-T8462
| 1mg | 39.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 459.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
MY-5445
CAS:78351-75-4
MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).
Formula:
C20H14ClN3
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
331.8
Ref: TM-T16164
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 140.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Amino Tadalafil
CAS:385769-84-6
Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.
Formula:
C21H18N4O4
Purity:
99.45%
Color and Shape:
White Powder
Molecular weight:
390.39
Ref: TM-T7542
| 10mg | 42.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 97.00 € | ||
| 100mg | 154.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Sildenafil Mesylate
CAS:1308285-21-3
Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.
Formula:
C22H30N6O4S·xCH4O3S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
570.68
Ref: TM-T6983
| 25mg | 35.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 3 Apr 2025
Lodenafil
CAS:139755-85-4
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
Formula:
C23H32N6O5S
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
504.6
Ref: TM-T7346
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 259.00 € | ||
| 200mg | 373.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
![[11C]MP 10](https://static.cymitquimica.com/products/TM/thumb/T6042.jpg)
[11C]MP 10
CAS:1292799-56-4
[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold …
Formula:
C25H20N4O
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
391.45
Ref: TM-T6042
| 1mg | 60.00 € | ||
| 2mg | 97.00 € | ||
| 5mg | 192.00 € | ||
| 10mg | 265.00 € | ||
| 25mg | 432.00 € | ||
| 50mg | 635.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Mirodenafil dihydrochloride
CAS:862189-96-6
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
Formula:
C26H39Cl2N5O5S
Purity:
99.64% - 99.78%
Color and Shape:
Solid
Molecular weight:
604.59
Ref: TM-TQ0126
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 131.00 € | ||
| 100mg | 202.00 € | ||
| 500mg | 470.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Osoresnontrine
CAS:1189767-28-9
Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be …
Formula:
C16H17N5O2
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T8515
| 1mg | 38.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € | ||
| 200mg | 748.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
CP671305
CAS:445295-04-5
CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.
Formula:
C23H19FN2O7
Purity:
99.22%
Color and Shape:
Solid
Molecular weight:
454.4
Ref: TM-T4695
| 1mg | 37.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Ziritaxestat
CAS:1628260-79-6
Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in …
Formula:
C30H33FN8O2S
Purity:
97% - 99.67%
Color and Shape:
Solid
Molecular weight:
588.7
Ref: TM-T4041
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 350.00 € | ||
| 200mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
PDE10-IN-1
CAS:1516896-09-5
PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.
Formula:
C21H19N7
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T5411
| 1mg | 74.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 386.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 702.00 € | ||
| 200mg | 949.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
RS-25344
CAS:152814-89-6
RS-25344: a strong PDE4 blocker, curbs eosinophil movement, boosts sperm motility in vitro.
Formula:
C19H13N5O4
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
375.34
Ref: TM-T9239
| 1mg | 88.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 810.00 € | ||
| 200mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Lotamilast
CAS:947620-48-6
Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment …
Formula:
C26H24N4O5
Purity:
97.03% - 99.29%
Color and Shape:
Solid
Molecular weight:
472.49
Ref: TM-T3987
| 1mg | 34.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 430.00 € | ||
| 200mg | 607.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
