PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
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Ketotifen fumarate
CAS:34580-14-8
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release …
Formula:
C23H23NO5S
Purity:
99.61% - ≥95%
Color and Shape:
Solid
Molecular weight:
425.5
Ref: TM-T0994
| 50mg | 38.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 68.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
ITI-214
CAS:1642303-38-5
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits …
Formula:
C29H29FN7O5P
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
605.56
Ref: TM-T11689
| 1mg | 73.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 297.00 € | ||
| 25mg | 524.00 € | ||
| 50mg | 733.00 € | ||
| 100mg | 1,040.00 € | ||
| 1mL*10mM (DMSO) | 217.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Pimobendan
CAS:74150-27-9
Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50: 0.32 μM).
Formula:
C19H18N4O2
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T1708
| 2mg | 38.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 398.00 € | ||
| 500mg | 906.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Carbodenafil
CAS:944241-52-5
Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor …
Formula:
C24H32N6O3
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
452.55
Ref: TM-T10676
| 1mg | 34.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 153.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
2-(Hydroxymethyl)pyridine
CAS:586-98-1
2-(Hydroxymethyl)pyridine (Piconol) is an intermediate for the synthesis of the stimulant laxative bisacodyl, and as …
Formula:
C6H7NO
Purity:
99.79%
Color and Shape:
Clear Light Yellow To Orange Liquid Liquid
Molecular weight:
109.13
Ref: TM-T1112
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Mirodenafil
CAS:862189-95-5
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
Formula:
C26H37N5O5S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
531.67
Ref: TM-T16079
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 333.00 € | ||
| 500mg | 782.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Roflumilast
CAS:162401-32-3
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), …
Formula:
C17H14Cl2F2N2O3
Purity:
100.00% - 99.64%
Color and Shape:
Solid
Molecular weight:
403.21
Ref: TM-T1024
| 5mg | 59.00 € | ||
| 10mg | 77.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 252.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Cilostazol
CAS:73963-72-1
Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is …
Formula:
C20H27N5O2
Purity:
99.86% - 99.87%
Color and Shape:
Off-White Solid
Molecular weight:
369.46
Ref: TM-T0462
| 25mg | 51.00 € | ||
| 50mg | 62.00 € | ||
| 100mg | 88.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
NSP-805
CAS:125068-54-4
NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.
Formula:
C17H19N3O2
Purity:
99.10%
Color and Shape:
Solid
Molecular weight:
297.35
Ref: TM-T12267
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 315.00 € | ||
| 50mg | 450.00 € | ||
| 100mg | 621.00 € | ||
| 200mg | 840.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MR-L2
CAS:2374703-19-0
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).
Formula:
C19H16Cl3FN4O
Purity:
98.09% - 98.94%
Color and Shape:
Solid
Molecular weight:
441.71
Ref: TM-T12103
| 1mg | 143.00 € | ||
| 2mg | 203.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 519.00 € | ||
| 25mg | 835.00 € | ||
| 50mg | 1,140.00 € | ||
| 100mg | 1,532.00 € | ||
| 500mg | 3,067.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
N-Methylbenzamide
CAS:613-93-4
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.
Formula:
C8H9NO
Purity:
99.83%
Color and Shape:
Physical Description Off-White Crystalline Solid (Ntp 1992)
Molecular weight:
135.16
Ref: TM-T12150
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Milrinone
CAS:78415-72-2
Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is …
Formula:
C12H9N3O
Purity:
99.92% - 99.93%
Color and Shape:
Solid
Molecular weight:
211.22
Ref: TM-T1096
| 25mg | 47.00 € | ||
| 50mg | 62.00 € | ||
| 100mg | 92.00 € | ||
| 200mg | 109.00 € | ||
| 500mg | 171.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Dipyridamole
CAS:58-32-2
Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means …
Formula:
C24H40N8O4
Purity:
100% - 99.47%
Color and Shape:
Solid
Molecular weight:
504.63
Ref: TM-T1618
| 50mg | 45.00 € | ||
| 100mg | 54.00 € | ||
| 200mg | 63.00 € | ||
| 500mg | 73.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
ATX inhibitor 1
CAS:2225892-70-4
ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, …
Formula:
C21H23Cl2N2O6P
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
501.3
Ref: TM-T10410
| 5mg | 47.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 186.00 € | ||
| 100mg | 308.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Enpp-1-IN-14
CAS:2687222-59-7
Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.
Formula:
C15H22ClN5O4S
Purity:
100%
Color and Shape:
Soild
Molecular weight:
403.88
Ref: TM-T60105
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 624.00 € | ||
| 100mg | 888.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
T-0156
CAS:324572-92-1
T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with …
Formula:
C31H29N5O7
Purity:
100% - 98.42%
Color and Shape:
Soild
Molecular weight:
583.59
Ref: TM-T23411L
| 1mg | 181.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 643.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 1,828.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ent-Tadalafil
CAS:629652-72-8
ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).
Formula:
C22H19N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-T11206
| 25mg | 735.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Pumafentrine
CAS:207993-12-2
Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in …
Formula:
C29H39N3O3
Purity:
99.79%
Color and Shape:
Liquid
Molecular weight:
477.64
Ref: TM-T71691
| 1mg | 183.00 € | ||
| 5mg | 435.00 € | ||
| 10mg | 635.00 € | ||
| 25mg | 1,000.00 € | ||
| 50mg | 1,336.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
UK 227786
CAS:150452-21-4
UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.
Formula:
C22H22Cl2N4O4
Purity:
100%
Color and Shape:
Soild
Molecular weight:
477.34
Ref: TM-T11220L
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,040.00 € | ||
| 500mg | 2,098.00 € | ||
| 1mL*10mM (DMSO) | 302.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 …
Formula:
C30H40Cl2N6O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
683.71
Ref: TM-T10994L
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
