PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
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Milrinone
CAS:78415-72-2
Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is …
Formula:
C12H9N3O
Purity:
99.22% - 99.92%
Color and Shape:
Solid
Molecular weight:
211.22
Ref: TM-T1096
| 25mg | 43.00 € | ||
| 50mg | 57.00 € | ||
| 100mg | 88.00 € | ||
| 200mg | 106.00 € | ||
| 500mg | 168.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Pimobendan
CAS:74150-27-9
Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50: 0.32 μM).
Formula:
C19H18N4O2
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T1708
| 2mg | 38.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 406.00 € | ||
| 500mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Carbodenafil
CAS:944241-52-5
Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor …
Formula:
C24H32N6O3
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
452.55
Ref: TM-T10676
| 1mg | 34.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 158.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
2-(Hydroxymethyl)pyridine
CAS:586-98-1
2-(Hydroxymethyl)pyridine (Piconol) is an intermediate for the synthesis of the stimulant laxative bisacodyl, and as …
Formula:
C6H7NO
Purity:
99.79%
Color and Shape:
Clear Light Yellow To Orange Liquid Liquid
Molecular weight:
109.13
Ref: TM-T1112
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Roflumilast
CAS:162401-32-3
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), …
Formula:
C17H14Cl2F2N2O3
Purity:
100.00% - 99.76%
Color and Shape:
Solid
Molecular weight:
403.21
Ref: TM-T1024
| 5mg | 55.00 € | ||
| 10mg | 73.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 250.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Mirodenafil
CAS:862189-95-5
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
Formula:
C26H37N5O5S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
531.67
Ref: TM-T16079
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 338.00 € | ||
| 500mg | 800.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
NSP-805
CAS:125068-54-4
NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.
Formula:
C17H19N3O2
Purity:
99.10%
Color and Shape:
Solid
Molecular weight:
297.35
Ref: TM-T12267
| 1mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 645.00 € | ||
| 200mg | 872.00 € | ||
| 1mL*10mM (DMSO) | 128.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Cilostazol
CAS:73963-72-1
Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is …
Formula:
C20H27N5O2
Purity:
99.58% - 99.90%
Color and Shape:
Off-White Solid
Molecular weight:
369.46
Ref: TM-T0462
| 25mg | 47.00 € | ||
| 50mg | 58.00 € | ||
| 100mg | 85.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
MR-L2
CAS:2374703-19-0
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).
Formula:
C19H16Cl3FN4O
Purity:
98.09% - 98.94%
Color and Shape:
Solid
Molecular weight:
441.71
Ref: TM-T12103
| 1mg | 145.00 € | ||
| 2mg | 207.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 852.00 € | ||
| 50mg | 1,159.00 € | ||
| 100mg | 1,568.00 € | ||
| 500mg | 3,125.00 € | ||
| 1mL*10mM (DMSO) | 378.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Zatolmilast
CAS:1606974-33-7
Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and …
Formula:
C21H15ClF3NO2
Purity:
98.20%
Color and Shape:
Solid
Molecular weight:
405.8
Ref: TM-T10590
| 1mg | 70.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 409.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 149.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
N-Methylbenzamide
CAS:613-93-4
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.
Formula:
C8H9NO
Purity:
99.83%
Color and Shape:
Physical Description Off-White Crystalline Solid (Ntp 1992)
Molecular weight:
135.16
Ref: TM-T12150
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Ketotifen fumarate
CAS:34580-14-8
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release …
Formula:
C23H23NO5S
Purity:
99.25% - 99.73%
Color and Shape:
Solid
Molecular weight:
425.5
Ref: TM-T0994
| 50mg | 38.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 69.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Dipyridamole
CAS:58-32-2
Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means …
Formula:
C24H40N8O4
Purity:
99.47% - 99.75%
Color and Shape:
Solid
Molecular weight:
504.63
Ref: TM-T1618
| 50mg | 46.00 € | ||
| 100mg | 55.00 € | ||
| 200mg | 64.00 € | ||
| 500mg | 73.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
ATX inhibitor 1
CAS:2225892-70-4
ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, …
Formula:
C21H23Cl2N2O6P
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
501.3
Ref: TM-T10410
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 311.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
ITI-214
CAS:1642303-38-5
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits …
Formula:
C29H29FN7O5P
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
605.56
Ref: TM-T11689
| 1mg | 74.00 € | ||
| 2mg | 97.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 303.00 € | ||
| 25mg | 533.00 € | ||
| 50mg | 750.00 € | ||
| 100mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 217.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Arofylline
CAS:136145-07-8
Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.
Formula:
C14H13ClN4O2
Purity:
97.98%
Color and Shape:
Liquid
Molecular weight:
304.73
Ref: TM-T9816
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,311.00 € | ||
| 1mL*10mM (DMSO) | 409.00 € |
Estimated delivery in United States, on Friday 2 May 2025
T-0156
CAS:324572-92-1
T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with …
Formula:
C31H29N5O7
Purity:
100% - 98.42%
Color and Shape:
Soild
Molecular weight:
583.59
Ref: TM-T23411L
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Vardenafil dihydrochloride
CAS:224789-15-5
Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 …
Formula:
C23H34Cl2N6O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
561.52
Ref: TM-T4480
| 25mg | 50.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 150.00 € | ||
| 200mg | 256.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 2 May 2025
WAY-313170
CAS:314041-83-3
WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.
Formula:
C19H17ClN2O2S2
Purity:
99.3%
Color and Shape:
Liquid
Molecular weight:
404.93
Ref: TM-T77603
| 1mg | 48.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 605.00 € | ||
| 200mg | 817.00 € | ||
| 500mg | 2,023.00 € |
Estimated delivery in United States, on Friday 2 May 2025
BAY 2666605
CAS:2275774-60-0
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 …
Formula:
C17H12F4N2O2
Purity:
99.98%
Color and Shape:
Liquid
Molecular weight:
352.28
Ref: TM-T9805
| 1mg | 97.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 828.00 € | ||
| 50mg | 1,320.00 € | ||
| 100mg | 2,118.00 € | ||
| 1mL*10mM (DMSO) | 259.00 € |
Estimated delivery in United States, on Friday 2 May 2025
