Transferase
Transferases are a large class of enzymes that catalyze the transfer of functional groups, such as methyl, glycosyl, and phosphate groups, from one molecule to another. Inhibitors of transferases are used to study a wide range of biological processes, including signal transduction, metabolism, and gene expression. These inhibitors are essential tools in research areas such as cancer, metabolic diseases, and epigenetics, where dysregulation of transferase activity is implicated. At CymitQuimica, we offer a comprehensive selection of transferase inhibitors to support your research in enzymology, cell signaling, and disease mechanisms.
Found 30 products of "Transferase"
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Cycloleucine
CAS:<p>Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.</p>Formula:C6H11NO2Purity:99.90%Color and Shape:SolidMolecular weight:129.16Opicapone
CAS:<p>Opicapone (BIA 9-1067), a potent COMT inhibitor for Parkinson's studies, lowers cell ATP (IC50: 98 μM).</p>Formula:C15H10Cl2N4O6Purity:98.17% - 99.36%Color and Shape:SolidMolecular weight:413.17Sinbaglustat
CAS:<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formula:C11H23NO4Purity:99.93%Color and Shape:SolidMolecular weight:233.3Histamine glutarimide
CAS:<p>Histamine glutarimide is a novel QPCT inhibitor that targets inflammatory processes like eosinophil migration, showing anti-asthmatic effects in animal models.</p>Formula:C10H13N3O2Purity:99.79%Color and Shape:SolidMolecular weight:207.23FUT8-IN-1
<p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>Formula:C23H25ClN2OColor and Shape:SolidMolecular weight:380.91β-1,4-GALT1-IN-1
<p>β-1,4-GALT1-IN-1 (Compound 6) is a β-1,4-GALT1 inhibitor with an IC50 value of 6.2 μM. It is applicable in studying various pathological conditions, including cancer, autoimmune diseases, and viral infections.</p>Formula:C29H23NO10Color and Shape:SolidMolecular weight:545.494ST6 Sialyltransferase 5
<p>ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.</p>L-739750 2HCl
<p>L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.</p>Formula:C23H41Cl2N3O6S2Purity:98.69% - 99.16%Color and Shape:SoildMolecular weight:590.62Tipifarnib
CAS:<p>Tipifarnib (IND 58359), a quinolinone, inhibits farnesyl transferase, blocks Ras activation, arrests cell growth, and curbs angiogenesis.</p>Formula:C27H22Cl2N4OPurity:97.1% - 99.22%Color and Shape:Off-White To Pale Beige SolidMolecular weight:489.4Ibiglustat
CAS:<p>Ibiglustat (GZ402671) inhibits Glucosylceramide synthase, may treat Fabry disease by preventing GL-3 synthesis.</p>Formula:C20H24FN3O2SPurity:97.97% - 98.81%Color and Shape:SolidMolecular weight:389.49Entacapone
CAS:<p>Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).</p>Formula:C14H15N3O5Purity:98.80% - >99.99%Color and Shape:Yellow Crystalline SolidMolecular weight:305.29Tipifarnib (S enantiomer)
CAS:<p>Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).</p>Formula:C27H22Cl2N4OPurity:99.05%Color and Shape:SolidMolecular weight:489.4PD 128042
CAS:<p>PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor.</p>Formula:C23H39NO4Purity:99.79%Color and Shape:SolidMolecular weight:393.56CP-609754
CAS:<p>CP-609754 shows selective inhibition of farnesyltransferase.</p>Formula:C29H22ClN3O2Purity:99.04% - 99.86%Color and Shape:SolidMolecular weight:479.96Nitecapone
CAS:<p>Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)</p>Formula:C12H11NO6Purity:98.39%Color and Shape:SolidMolecular weight:265.22Ervogastat
CAS:<p>Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor.</p>Formula:C21H21N5O4Purity:99.97%Color and Shape:SolidMolecular weight:407.423-O-Methyltolcapone
CAS:<p>3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.</p>Formula:C15H13NO5Purity:98%Color and Shape:SolidMolecular weight:287.27AMP-Deoxynojirimycin
CAS:<p>AMP-Deoxynojirimycin (AMP-DNM) is a ceramide glucosyltransferase and GCase 2 inhibitor for the study of Parkinson's and diabetes.</p>Formula:C22H39NO5Purity:>99.99%Color and Shape:SolidMolecular weight:397.55Lucerastat
CAS:<p>Lucerastat（NBDGJ） is an orally available inhibitor of GCS for Fabry disease by reducing harmful substrates.. GCS is a key enzyme in sphingolipid synthesiss.</p>Formula:C10H21NO4Purity:98%Color and Shape:SolidMolecular weight:219.28P-3FAX-Neu5Ac
CAS:<p>P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.</p>Formula:C22H30FNO14Purity:97.08%Color and Shape:SolidMolecular weight:551.47Prenyl-IN-1
CAS:<p>Prenyl-IN-1 inhibits prenylation selectively, counters oxidative stress in Parkinson's.</p>Formula:C28H24ClN5O2Purity:>99.99%Color and Shape:SolidMolecular weight:497.98α-2,3-sialyltransferase-IN-1
CAS:<p>α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).</p>Formula:C28H45NO6Purity:98% - 98%Color and Shape:SolidMolecular weight:491.66Ibiglustat (L-Malic acid)
CAS:<p>Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase.</p>Formula:C24H30FN3O7SPurity:99.54%Color and Shape:SolidMolecular weight:523.57OSMI-1
CAS:<p>OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.</p>Formula:C28H25N3O6S2Purity:96.79% - 99.39%Color and Shape:SolidMolecular weight:563.64Miglustat hydrochloride
CAS:<p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>Formula:C10H22ClNO4Purity:99.85%Color and Shape:SolidMolecular weight:255.74FGTI-2734
CAS:<p>FGTI-2734, a dual FT/GGT-1 inhibitor (IC50: 250/520 nM), blocks KRAS membrane binding and curbs KRAS-driven pancreatic cancer.</p>Formula:C26H31FN6O2SPurity:99.69%Color and Shape:SolidMolecular weight:510.63BMS-214662 mesylate
CAS:<p>BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.</p>Formula:C26H27N5O5S3Color and Shape:SolidMolecular weight:585.718ICMT-IN-55
CAS:<p>ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].</p>Formula:C22H26F3NO2Color and Shape:SolidMolecular weight:393.44Glucosylceramide synthase-IN-4
CAS:<p>Glucosylceramide Synthase-IN-4 (compound 12) serves as a potent inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 of 6.8 nM. It demonstrates superior pharmacokinetic properties and robust stability in human hepatocytes. Additionally, this compound is noted for its effective CNS penetration and acceptable PXR selectivity [1].</p>Formula:C22H18F5N3O3Color and Shape:SolidMolecular weight:467.39Darlifarnib
CAS:<p>Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.</p>Formula:C29H20N6OColor and Shape:SolidMolecular weight:468.509
