Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 267 products of "Dehydrogenase"
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LDH-IN-1
CAS:<p>LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).</p>Formula:C30H26N4O4S2Purity:99.6%Color and Shape:SolidMolecular weight:570.68Mutant IDH1 inhibitor
CAS:<p>Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).</p>Formula:C25H34N6O3Purity:98.3%Color and Shape:SolidMolecular weight:466.58DHODH-IN-11
CAS:<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Formula:C15H11N3O2Purity:98.14%Color and Shape:SolidMolecular weight:265.27CVT-10216
CAS:<p>CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.</p>Formula:C24H19NO7SPurity:98.76%Color and Shape:SolidMolecular weight:465.48BAY-2402234
CAS:<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Formula:C21H18ClF5N4O4Purity:98.9%Color and Shape:SolidMolecular weight:520.84Olutasidenib
CAS:<p>Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.</p>Formula:C18H15ClN4O2Purity:98.57%Color and Shape:SolidMolecular weight:354.79SCD1 inhibitor-4
CAS:<p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>Formula:C17H16F3N5OPurity:99.71%Color and Shape:SolidMolecular weight:363.344-Diethylaminobenzaldehyde
CAS:<p>4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).</p>Formula:C11H15NOPurity:99.6%Color and Shape:Brown-Black CrystalsMolecular weight:177.24ML390
CAS:<p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>Formula:C21H21F3N2O3Purity:99.76%Color and Shape:SolidMolecular weight:406.4CAY10566
CAS:<p>CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.</p>Formula:C18H17ClFN5O2Purity:99.5% - 99.54%Color and Shape:SolidMolecular weight:389.81GSK2837808A
CAS:<p>GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).</p>Formula:C31H25F2N5O7SPurity:99.78% - 99.78%Color and Shape:SolidMolecular weight:649.62MF-438
CAS:<p>MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).</p>Formula:C19H18F3N5OSPurity:98.98% - 99.50%Color and Shape:SolidMolecular weight:421.44Mycophenolic acid
CAS:<p>Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.</p>Formula:C17H20O6Purity:98.79% - 99.77%Color and Shape:SolidMolecular weight:320.34NCT-502
CAS:<p>NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,</p>Formula:C18H20F3N5SPurity:99.60%Color and Shape:SolidMolecular weight:395.45Trilostane
CAS:<p>Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.</p>Formula:C20H27NO3Purity:99.46% - >99.99%Color and Shape:Tan CrystalsMolecular weight:329.43CBR-5884
CAS:<p>CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.</p>Formula:C14H12N2O4S2Purity:99.97%Color and Shape:SolidMolecular weight:336.39RS 61443
CAS:<p>RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)</p>Formula:C23H31NO7Purity:99.37% - 99.91%Color and Shape:SolidMolecular weight:433.5Adrenosterone
CAS:<p>Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.</p>Formula:C19H24O3Purity:98.13% - 98.29%Color and Shape:SolidMolecular weight:300.39KPLH1130
CAS:<p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>Formula:C15H13N3O3Purity:99.07%Color and Shape:SolidMolecular weight:283.28LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Formula:C20H21N7O7Purity:99.7%Color and Shape:SolidMolecular weight:471.42PTC299
CAS:<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Formula:C25H20Cl2N2O3Purity:99.72%Color and Shape:SolidMolecular weight:467.34IDH-305
CAS:<p>IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.</p>Formula:C23H22F4N6O2Purity:99.68%Color and Shape:SolidMolecular weight:490.45XEN723
CAS:<p>XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).</p>Formula:C21H20FN5O2SPurity:99.5%Color and Shape:SolidMolecular weight:425.48Antiproliferative agent-13
CAS:<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Formula:C20H18N2O6Purity:99.723%Color and Shape:SolidMolecular weight:382.37DSM705
CAS:<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Formula:C19H19F3N6OColor and Shape:SolidMolecular weight:404.397Diethanolamine hydrochloride
CAS:<p>Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.</p>Formula:C4H12ClNO2Purity:99.69%Color and Shape:SolidMolecular weight:141.6DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Formula:C24H25FN4O3Purity:99.64%Color and Shape:SolidMolecular weight:436.48WAY-311610
CAS:<p>WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.</p>Formula:C16H13F3N4O2Purity:98.01%Color and Shape:SolidMolecular weight:350.3hDHODH-IN-8
CAS:<p>hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.</p>Formula:C21H15F6N3O4Purity:98%Color and Shape:SoildMolecular weight:487.3511β-HSD1 inibitor 19
CAS:<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Formula:C19H16ClF4N3O2SPurity:99.58%Color and Shape:SoildMolecular weight:461.86hDHODH-IN-12
<p>hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.</p>Formula:C22H15F3N4O3Purity:98%Color and Shape:SolidMolecular weight:440.37LDHA-IN-8
CAS:<p>LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.</p>Formula:C15H14N4O2Purity:99.73%Color and Shape:SolidMolecular weight:282.3IGUANA-1
CAS:<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Formula:C27H26ClN3O4Purity:99.08%Color and Shape:SolidMolecular weight:491.97DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formula:C24H21ClFNO4Purity:99.7%Color and Shape:SolidMolecular weight:441.88Nedosiran sodium
CAS:<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Color and Shape:SolidMTHFD2-IN-3
<p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>Formula:C22H19NO7SColor and Shape:SolidMolecular weight:441.452,3-Dihydroxybenzaldehyde
CAS:<p>2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.</p>Formula:C7H6O3Color and Shape:SolidMolecular weight:138.12Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Formula:C29H49N7NaO17P3SColor and Shape:SolidMolecular weight:915.71PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Formula:C17H23AsCl2N2O2S2Color and Shape:SolidMolecular weight:497.3311β-HSD1 inibitor 17
CAS:<p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>Formula:C22H20F3N3O2SPurity:99.26% - 99.72%Color and Shape:SoildMolecular weight:447.4711β-HSD1-IN-11
CAS:<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>Formula:C15H11F3O3SPurity:99.61%Color and Shape:SoildMolecular weight:328.31MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Formula:C26H21F6N2NaO5Color and Shape:SolidMolecular weight:578.44MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Formula:C26H21F6N2O5Color and Shape:SolidMolecular weight:555.45IGUANA-1 free base
CAS:<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Formula:C26H24ClN3O2Color and Shape:SolidMolecular weight:445.94PDK-IN-1
CAS:<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Formula:C20H16BrN7OColor and Shape:SolidMolecular weight:450.29MTHFD2-IN-2
<p>MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formula:C22H18N4O5Color and Shape:SolidMolecular weight:418.4Necroptosis-IN-3
CAS:<p>Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.</p>Formula:C12H17NOSPurity:99.85%Color and Shape:SoildMolecular weight:223.33CM121
CAS:<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Formula:C24H17FN4O3SColor and Shape:SolidMolecular weight:460.4818β-Glycyrrhetyl-3-O-sulfate
CAS:<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Formula:C30H46O7SColor and Shape:SolidMolecular weight:550.75MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formula:C24H21NO6Color and Shape:SolidMolecular weight:419.43DHODH-IN-18
CAS:<p>DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).</p>Formula:C21H16ClF5N6O4Color and Shape:SolidMolecular weight:546.84SKI2852
CAS:<p>SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.</p>Formula:C27H34FN5O4SPurity:99.89%Color and Shape:SolidMolecular weight:543.6517β-HSD10-IN-1
CAS:<p>17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.</p>Formula:C16H13ClN4O3SPurity:98.47%Color and Shape:SoildMolecular weight:376.82LDHA-IN-3
CAS:<p>LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.</p>Formula:C13H9F3SePurity:99.71%Color and Shape:SolidMolecular weight:301.17TC HSD 21
CAS:<p>TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).</p>Formula:C17H12BrNO3S2Purity:98.5%Color and Shape:SolidMolecular weight:422.32Ascochlorin A
CAS:<p>Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor</p>Formula:C23H31ClO4Color and Shape:SolidMolecular weight:406.95SW209049
CAS:<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Formula:C25H18N2O4SPurity:99.72%Color and Shape:SolidMolecular weight:442.49KOTX1
CAS:<p>KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.</p>Formula:C17H16FN3O2Color and Shape:SolidMolecular weight:313.33hDHODH-IN-13
CAS:<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Color and Shape:SoildhDHODH-IN-16
<p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>Formula:C18H20N2O2Color and Shape:SolidMolecular weight:296.36SCD1 inhibitor-3
CAS:<p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>Formula:C19H16FN7O2Purity:99.5%Color and Shape:SolidMolecular weight:393.37BVT-2733 hydrochloride
CAS:<p>BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.</p>Formula:C17H22Cl2N4O3S2Color and Shape:SolidMolecular weight:465.42D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Color and Shape:SolidOsmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Formula:C19H28O11Color and Shape:SolidMolecular weight:432.422MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Formula:C21H15N3O4Color and Shape:SolidMolecular weight:373.36(Rac)-BMS-816336
<p>(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.</p>Formula:C21H27NO3Purity:98%Color and Shape:SolidMolecular weight:341.44DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Formula:C17H12ClF6N5O2Color and Shape:SolidMolecular weight:467.753BMS-770767
CAS:<p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>Formula:C19H18ClN3O2Color and Shape:SolidMolecular weight:355.82Crelosidenib
CAS:<p>Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.</p>Formula:C28H36N6O3Purity:98.54%Color and Shape:SolidMolecular weight:504.62ALDH1A2-IN-1
CAS:<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Formula:C21H26N4O4SPurity:99.51%Color and Shape:SolidMolecular weight:430.52ALDH3A1-IN-1
CAS:<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Formula:C13H18N2O3Purity:99.86%Color and Shape:SolidMolecular weight:250.29Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Color and Shape:SolidABT-384
CAS:<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Formula:C25H34F3N5O2Purity:99.863%Color and Shape:SolidMolecular weight:493.58ALDH1A3-IN-1
CAS:<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Formula:C13H18BrNOColor and Shape:SolidMolecular weight:284.192-Bromoacetamide
CAS:<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Formula:C2H4BrNOPurity:99.83%Color and Shape:SolidMolecular weight:137.96DSM265
CAS:<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Formula:C14H12F7N5SPurity:99.79%Color and Shape:SolidMolecular weight:415.334-Isopropoxybenzaldehyde
CAS:<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Formula:C10H12O2Purity:99.00%Color and Shape:SolidMolecular weight:164.2DSM502
CAS:<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Formula:C16H16F3N3OPurity:99.52%Color and Shape:SolidMolecular weight:323.31Ketogestin
CAS:<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Formula:C21H28O3Purity:99.19%Color and Shape:SolidMolecular weight:328.45PKUMDL-WQ-2201
CAS:<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Formula:C15H14ClN3O3SColor and Shape:SolidMolecular weight:351.81Perfluorooctanoic acid
CAS:<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Formula:C8HF15O2Purity:99.70%Color and Shape:White To Off-White Powder OthersolidMolecular weight:414.07Nitrofurazone
CAS:<p>Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.</p>Formula:C6H6N4O4Purity:99.87%Color and Shape:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Molecular weight:198.14DS-1001b
CAS:<p>DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)</p>Formula:C29H29Cl3FN3O4Purity:99.81%Color and Shape:SolidMolecular weight:608.92Dihydrouracil
CAS:<p>5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.</p>Formula:C4H6N2O2Purity:99.75%Color and Shape:SolidMolecular weight:114.1AZD7545
CAS:<p>AZD7545 is a potent PDHK inhibitor.</p>Formula:C19H18ClF3N2O5SPurity:99.12% - 99.96%Color and Shape:SolidMolecular weight:478.87BI-187004
CAS:<p>BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.</p>Formula:C21H18N4OPurity:98.63%Color and Shape:SolidMolecular weight:342.39PfDHODH-IN-2
CAS:<p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>Formula:C13H12ClNO3SPurity:98.9%Color and Shape:SolidMolecular weight:297.76AGI-6780
CAS:<p>AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.</p>Formula:C21H18F3N3O3S2Purity:98.19% - 99.7%Color and Shape:SolidMolecular weight:481.51Nitrofen
CAS:<p>Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.</p>Formula:C12H7Cl2NO3Purity:99.92%Color and Shape:Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicideMolecular weight:284.09LDHA-IN-4
CAS:<p>LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.</p>Formula:C25H27N3O6SPurity:98.17% - 99.68%Color and Shape:SolidMolecular weight:497.56BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formula:C17H21ClN4O3S2Purity:98% - 99.64%Color and Shape:SolidMolecular weight:428.96PfDHODH-IN-1
CAS:<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formula:C14H11F3N2O2Purity:99.87%Color and Shape:SolidMolecular weight:296.24AKR1C3-IN-1
CAS:<p>AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).</p>Formula:C16H15NO4SPurity:98.02%Color and Shape:SolidMolecular weight:317.36AKR1C3-IN-4
CAS:<p>AKR1C3-IN-4: potent, selective AKR1C3 inhibitor, IC50 = 0.56 μM, potential for CRPC research.</p>Formula:C14H10F3NO2Purity:98.59%Color and Shape:SolidMolecular weight:281.23BMS-823778 hydrochloride
CAS:<p>BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half</p>Formula:C18H19Cl2N3OColor and Shape:SolidMolecular weight:364.27G6PDi-1
CAS:<p>G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.</p>Formula:C14H12N4OSPurity:98.69%Color and Shape:SolidMolecular weight:284.34R162
CAS:<p>R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.</p>Formula:C17H12O3Purity:96.21% - 98.15%Color and Shape:SolidMolecular weight:264.28(E/Z)-Teriflunomide
CAS:<p>(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.</p>Formula:C12H9F3N2O2Purity:99.49% - 99.76%Color and Shape:White SolidMolecular weight:270.21Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37PHGDH-inactive
CAS:<p>PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].</p>Formula:C17H21N5SPurity:99.83%Color and Shape:SolidMolecular weight:327.45Carbenoxolone disodium
CAS:<p>Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.</p>Formula:C34H48Na2O7Purity:99.69%Color and Shape:SolidMolecular weight:614.72MK-8245
CAS:<p>MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.</p>Formula:C17H16BrFN6O4Purity:97.58% - 99%Color and Shape:SolidMolecular weight:467.25NCT-501 hydrochloride
CAS:<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Formula:C21H33ClN6O3Color and Shape:SolidMolecular weight:452.98Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formula:C20H18FNO4CaColor and Shape:SolidMolecular weight:375.4AG-636
CAS:<p>AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.</p>Formula:C21H17N3O2Purity:99.19%Color and Shape:SolidMolecular weight:343.38Sodium dichloroacetate
CAS:<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Formula:C2HCl2NaO2Purity:99.32% - 99.87%Color and Shape:White PowderMolecular weight:150.92A939572
CAS:<p>A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.</p>Formula:C20H22ClN3O3Purity:99.96% - ≥95%Color and Shape:SolidMolecular weight:387.86Proguanil hydrochloride
CAS:<p>Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.</p>Formula:C11H17Cl2N5Purity:98.34% - 98.39%Color and Shape:SolidMolecular weight:290.19Ivosidenib
CAS:<p>Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.</p>Formula:C28H22ClF3N6O3Purity:98.71% - 99.98%Color and Shape:SolidMolecular weight:582.96Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Formula:C9H12N2O5SPurity:99.91%Color and Shape:SolidMolecular weight:260.27Galloflavin
CAS:<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Formula:C12H6O8Purity:96.24% - 97.47%Color and Shape:SolidMolecular weight:278.17NCT-505
CAS:<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Formula:C27H28FN5O3SPurity:99.93%Color and Shape:SolidMolecular weight:521.61VER-246608
CAS:<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Formula:C28H23ClF2N4O4Purity:98.5%Color and Shape:SolidMolecular weight:552.96Mutant IDH1-IN-1
CAS:<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Formula:C30H31FN4O2Purity:99.49% - >99.99%Color and Shape:SolidMolecular weight:498.59NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formula:C20H23F3N4SPurity:98.91% - 99.84%Color and Shape:SolidMolecular weight:408.48L-Allylglycine
CAS:<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Formula:C5H9NO2Purity:≥98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:115.13CM10
CAS:<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Formula:C20H23N3OPurity:99.84%Color and Shape:SolidMolecular weight:321.42NCT-501
CAS:<p>NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.</p>Formula:C21H32N6O3Purity:99.19%Color and Shape:SolidMolecular weight:416.52AGI-5198
CAS:<p>AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).</p>Formula:C27H31FN4O2Purity:97.37% - 99.23%Color and Shape:SolidMolecular weight:462.56Nifurtimox
CAS:<p>Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.</p>Formula:C10H13N3O5SPurity:99.87% - 99.89%Color and Shape:SolidMolecular weight:287.29BAY-1436032
CAS:<p>BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).</p>Formula:C26H30F3N3O3Purity:99.65% - 99.71%Color and Shape:SolidMolecular weight:489.53WIN 18446
CAS:<p>inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)</p>Formula:C12H20Cl4N2O2Purity:99.69%Color and Shape:SolidMolecular weight:366.11Brequinar sodium
CAS:<p>Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.</p>Formula:C23H14F2NNaO2Purity:98.16%Color and Shape:SolidMolecular weight:397.36Fomepizole
CAS:<p>Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.</p>Formula:C4H6N2Purity:98.1% - 99.94%Color and Shape:Yellow <13°C Solid >13°C LiquidMolecular weight:82.1Imidazole-5-propionic acid
CAS:<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Formula:C6H8N2O2Purity:99.62%Color and Shape:SolidMolecular weight:140.14AG-120 (racemic)
CAS:<p>AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.</p>Formula:C28H22ClF3N6O3Purity:99.56%Color and Shape:SolidMolecular weight:582.96Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formula:C20H18FNO4Purity:98.33% - 99.58%Color and Shape:SolidMolecular weight:355.36BVT-14225
CAS:<p>BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).</p>Formula:C16H20ClN3O3S2Purity:97.78%Color and Shape:SolidMolecular weight:401.93(R)-GNE-140
CAS:<p>(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.</p>Formula:C25H23ClN2O3S2Purity:98.25% - 98.91%Color and Shape:SolidMolecular weight:499.04Succinyl phosphonate trisodium salt
CAS:<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>Formula:C4H4Na3O6PPurity:99.8% - ≥95%Color and Shape:SolidMolecular weight:248.01SW033291
CAS:<p>SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.</p>Formula:C21H20N2OS3Purity:97.26% - 99.02%Color and Shape:SolidMolecular weight:412.593-Hydroxybenzaldehyde
CAS:<p>3-Hydroxybenzaldehyde is a compound useful in organic synthesis.</p>Formula:C7H6O2Purity:99.60%Color and Shape:DrypowderMolecular weight:122.126PGD-IN-S3
CAS:<p>6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).</p>Formula:C15H10O4Purity:99.12%Color and Shape:SolidMolecular weight:254.24Enasidenib
CAS:<p>Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential</p>Formula:C19H17F6N7OPurity:98% - >99.99%Color and Shape:SolidMolecular weight:473.38Enasidenib mesylate
CAS:<p>Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.</p>Formula:C20H21F6N7O4SPurity:99.86%Color and Shape:SolidMolecular weight:569.48DS44960156
CAS:<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Formula:C20H15NO5Purity:99.13%Color and Shape:SolidMolecular weight:349.34GSK1940029
CAS:<p>GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.</p>Formula:C18H16Cl2N4O2Purity:99.48% - 99.49%Color and Shape:SolidMolecular weight:391.25Triflupromazine
CAS:<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Formula:C18H19F3N2SColor and Shape:SolidMolecular weight:352.42hDHODH-IN-2
CAS:<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Formula:C19H16N2O2Purity:98%Color and Shape:SolidMolecular weight:304.349Nitrophenide
CAS:<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Formula:C12H8N2O4S2Purity:99.78%Color and Shape:SolidMolecular weight:308.33AGI-14100
CAS:<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Formula:C29H22ClF4N5O3Purity:99.91%Color and Shape:SolidMolecular weight:599.96Epostane
CAS:<p>Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.</p>Formula:C22H31NO3Purity:>99.99%Color and Shape:SolidMolecular weight:357.49DHODH-IN-24
CAS:<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Formula:C26H26N4Color and Shape:SolidMolecular weight:394.51IMB-XMA0038
CAS:<p>IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.</p>Formula:C11H10N4O6Purity:98.94% - 99.96%Color and Shape:SolidMolecular weight:294.22BI-4924
CAS:<p>BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.</p>Formula:C21H20Cl2N2O6SPurity:99.55%Color and Shape:SolidMolecular weight:499.36NCT-506
CAS:<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Formula:C25H23FN4O3SPurity:98%Color and Shape:SolidMolecular weight:478.54SCH-451659
CAS:<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Formula:C30H39Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:544.56BI-135585
CAS:<p>BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.</p>Formula:C28H32N2O4Purity:99.45% - 99.57%Color and Shape:SolidMolecular weight:460.57CM026
CAS:<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Formula:C22H30N6O4Color and Shape:SolidMolecular weight:442.51ML387
CAS:<p>ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Formula:C20H21N3O2Purity:98%Color and Shape:SolidMolecular weight:335.4Oxycinchophen
CAS:<p>Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.</p>Formula:C16H11NO3Purity:98%Color and Shape:SolidMolecular weight:265.26GW648495
CAS:<p>GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.</p>Formula:C16H13N5Purity:98%Color and Shape:SolidMolecular weight:275.31BVT-116429
CAS:<p>BVT-116429 is an inhibitor of 11β-HSD1.</p>Formula:C13H12F4N2OSPurity:98%Color and Shape:SolidMolecular weight:320.31GA11
CAS:<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Formula:C19H14N2Purity:98%Color and Shape:SolidMolecular weight:270.33RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Formula:C20H22N4O3SColor and Shape:SolidMolecular weight:398.48RORγt/DHODH-IN-2
CAS:<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Formula:C25H30N4OSColor and Shape:SolidMolecular weight:434.6UCK2 Inhibitor-2
CAS:<p>UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.</p>Formula:C28H23N3O4SPurity:98.76% - 99.25%Color and Shape:SolidMolecular weight:497.57DHODH-IN-20
CAS:<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Formula:C24H25F4N3O3Color and Shape:SolidMolecular weight:479.47hDHODH-IN-4
CAS:<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Formula:C21H24N4O2Purity:99.87%Color and Shape:SolidMolecular weight:364.44ALDH1A1-IN-3
CAS:<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Formula:C31H36F3N5O4Color and Shape:SolidMolecular weight:599.64AZD8329
CAS:<p>AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.</p>Formula:C25H31N3O3Purity:99.31%Color and Shape:SolidMolecular weight:421.53KM04416
CAS:<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formula:C12H11NO3SPurity:99.88%Color and Shape:SolidMolecular weight:249.29ALDH1A1-IN-2
CAS:<p>ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity</p>Formula:C25H23ClN4O3SPurity:99.48%Color and Shape:SolidMolecular weight:494.99Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formula:C15H13F3N2O2Purity:99.86%Color and Shape:SolidMolecular weight:310.27hDHODH-IN-9
CAS:<p>hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.</p>Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.4RV01
CAS:<p>RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.</p>Formula:C17H13NO2Purity:99.93%Color and Shape:SolidMolecular weight:263.29hDHODH-IN-3
CAS:<p>hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.</p>Formula:C18H19BrN4O2Purity:99.871%Color and Shape:SolidMolecular weight:403.27Genz-669178
CAS:<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Formula:C17H14N4OSPurity:98%Color and Shape:SolidMolecular weight:322.38EN40
CAS:<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Formula:C13H15NO2Color and Shape:SolidMolecular weight:217.26DHODH-IN-13
CAS:<p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>Formula:C10H6F3N3O3Purity:99.66%Color and Shape:SolidMolecular weight:273.17DHODH-IN-15
CAS:<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Formula:C15H11N3O3Purity:99.8%Color and Shape:SolidMolecular weight:281.27DHODH-IN-17
CAS:<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Formula:C12H9ClN2O2Purity:99.41% - 99.52%Color and Shape:SolidMolecular weight:248.67DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formula:C21H20F3N3O2Purity:99.76%Color and Shape:SolidMolecular weight:403.4hDHODH-IN-5
CAS:<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Formula:C21H21F3N2O2Purity:99.55%Color and Shape:SolidMolecular weight:390.4p-Valerylphenol
CAS:<p>p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.</p>Formula:C11H14O2Purity:99.87%Color and Shape:White To Light Beige PowderMolecular weight:178.23M77976
CAS:<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Formula:C17H16N2O3Purity:99.43%Color and Shape:SolidMolecular weight:296.32Manitimus
CAS:<p>Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.</p>Formula:C15H11F3N2O2Purity:99.75% - 99.75%Color and Shape:SolidMolecular weight:308.26Metapramine
CAS:<p>Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.</p>Formula:C16H18N2Purity:99.03% - 99.67%Color and Shape:SolidMolecular weight:238.3311β-HSD1-IN-1
CAS:<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Formula:C18H14ClF4N3OPurity:99.84%Color and Shape:SolidMolecular weight:399.77DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formula:C17H12Cl2N2O2Purity:99.34%Color and Shape:SolidMolecular weight:347.2DHODH-IN-8
CAS:<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Formula:C17H13ClN2O2Purity:99.78%Color and Shape:SolidMolecular weight:312.7511β-HSD1-IN-12
CAS:<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Formula:C19H27ClN2O3SPurity:99.68%Color and Shape:SolidMolecular weight:398.95Nitrefazole
CAS:<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Formula:C10H8N4O4Color and Shape:SolidMolecular weight:248.1911β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.86CM39
CAS:<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Formula:C19H15FN4OSColor and Shape:SolidMolecular weight:366.41MEDS433
CAS:<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Formula:C20H11F4N3O2Color and Shape:SolidMolecular weight:401.31hDHODH-IN-11
CAS:<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.46DHODH-IN-12
CAS:<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Formula:C10H9N3O2Purity:99.53%Color and Shape:SolidMolecular weight:203.2AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Formula:C14H22N2OSPurity:98%Color and Shape:SolidMolecular weight:266.411β-HSD1-IN-10
CAS:<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Formula:C16H10F3NO2Color and Shape:SolidMolecular weight:305.25673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formula:C22H18ClF6N3O3Color and Shape:SolidMolecular weight:521.84ASP3662
CAS:<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Formula:C19H16ClF3N4O2Color and Shape:SolidMolecular weight:424.8TM-1
CAS:<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Formula:C26H32N2O6Color and Shape:SolidMolecular weight:468.54DHODH-IN-3
CAS:<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formula:C17H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:312.75ALDH3A1-IN-2
CAS:<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Formula:C11H14N2O3Color and Shape:SolidMolecular weight:222.2411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formula:C13H9F3N2OColor and Shape:SolidMolecular weight:266.22DHODH-IN-21
CAS:<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Formula:C20H19ClF4N6O4Color and Shape:SolidMolecular weight:518.85BRD9185
CAS:<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Formula:C23H21F6N3O2Purity:98%Color and Shape:SolidMolecular weight:485.42P1788
CAS:<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3
