Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 133 products of "Lipoxygenase"
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Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurity:98.72% - 99.43%Color and Shape:Crystalline SolidMolecular weight:236.29Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Color and Shape:SolidMolecular weight:355.39CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purity:99.93%Color and Shape:SoildMolecular weight:247.72(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Formula:C20H26O4Color and Shape:SolidMolecular weight:330.42415-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Color and Shape:SolidMolecular weight:412.8713-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Color and Shape:SolidMolecular weight:292.41(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.505DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurity:97.08%Color and Shape:SoildMolecular weight:194.26CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purity:98%Color and Shape:SolidMolecular weight:322.33KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurity:99.44%Color and Shape:SolidMolecular weight:266.36Ref: TM-T77288
2mg37.00€5mg56.00€10mg84.00€25mg126.00€50mg197.00€100mg330.00€200mg472.00€1mL*10mM (DMSO)58.00€ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:397.44E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purity:99.80%Color and Shape:SoildMolecular weight:413.94Damnacanthol
Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.Formula:C16H12O5Color and Shape:SolidMolecular weight:284.2675-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColor and Shape:SolidMolecular weight:365.82Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formula:C22H24O11Color and Shape:SolidMolecular weight:464.4mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SMolecular weight:446.12601h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Color and Shape:SolidMolecular weight:497.42Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.351-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purity:99.79%Color and Shape:SolidMolecular weight:338.27Ref: TM-T21838
5mg54.00€10mg86.00€25mg161.00€50mg245.00€100mg346.00€200mg474.00€1mL*10mM (DMSO)55.00€Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Color and Shape:SolidMolecular weight:404.419
