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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5398 products of "Neuroscience"

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  • Amyloid β-Protein (1-24)

    CAS:
    <p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>
    Formula:C130H183N35O40
    Molecular weight:2876.05
  • (S)-3,4-DCPG HCl


    <p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>
    Formula:C10H10ClNO6
    Purity:99.53% - 99.9%
    Color and Shape:Soild
    Molecular weight:275.64
  • 7-Methyl DMT

    CAS:
    <p>7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.</p>
    Formula:C13H18N2
    Color and Shape:Solid
    Molecular weight:202.3
  • Rilmazolam

    CAS:
    <p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>
    Formula:C19H15Cl2N5O
    Color and Shape:Solid
    Molecular weight:400.26
  • Rapastinel acetate

    CAS:
    <p>Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.</p>
    Formula:C20H35N5O8
    Purity:99.6%
    Color and Shape:Soild
    Molecular weight:473.52
  • SB656104

    CAS:
    <p>SB656104 is a bioactive chemical.</p>
    Formula:C25H30ClN3O3S
    Color and Shape:Solid
    Molecular weight:488.04
  • Biphenyl-3′,3,4,4′-tetrol

    CAS:
    <p>Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.</p>
    Formula:C12H10O4
    Color and Shape:Solid
    Molecular weight:218.21
  • Rubrofusarin triglucoside

    CAS:
    <p>Rubrofusarin triglucoside, a glycoside from Cassia obtusifolia seeds, inhibits hMAO-A with an IC50 of 85.5 μM.</p>
    Formula:C33H42O20
    Color and Shape:Solid
    Molecular weight:758.679
  • (Rac)-Sabcomeline

    CAS:
    <p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>
    Formula:C10H15N3O
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:193.25
  • Davunetide acetate


    <p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>
    Formula:C38H64N10O14
    Purity:99.52% - 99.78%
    Color and Shape:Solid
    Molecular weight:884.97
  • β-Secretase Inhibitor II

    CAS:
    <p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>
    Formula:C25H39N3O5
    Color and Shape:Solid
    Molecular weight:461.59
  • Heliosupine N-oxide


    <p>Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.</p>
    Formula:C20H31NO8
    Color and Shape:Solid
    Molecular weight:413.467
  • AC 253

    CAS:
    <p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>
    Formula:C122H196N40O39
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2847.11
  • COX-1/2-IN-4


    <p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>
    Formula:C22H24N2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.5
  • NMDA receptor antagonist 8


    <p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>
    Formula:C22H27N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.47
  • Alosetron-d3

    CAS:
    <p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>
    Formula:C17H18N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.37
  • MAO-B-IN-4


    <p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>
    Formula:C23H20ClF2N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.87
  • Lysyl hydroxylase 2-IN-1


    <p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>
    Formula:C18H18N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.35
  • Perlapine

    CAS:
    <p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>
    Formula:C19H21N3
    Color and Shape:Solid
    Molecular weight:291.39
  • NMDA receptor antagonist 7


    <p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>
    Formula:C22H27N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.47
  • Navicixizumab

    CAS:
    <p>Navicixizumab, a bispecific VEGF/DLL4 inhibitor, pairs with Paclitaxel in ovarian and other cancer research.</p>
    Color and Shape:Liquid
  • β-Secretase Inhibitor I

    CAS:
    <p>β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.</p>
    Formula:C18H18F3N5O2S
    Color and Shape:Solid
    Molecular weight:425.43
  • Calmodulin Kinase IINtide, Myristoylated


    <p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>
    Formula:C156H275N47O43
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3497.14
  • β-Amyloid (10-20)

    CAS:
    <p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>
    Formula:C71H99N17O16
    Purity:98%
    Color and Shape:Lyophilized Powder
    Molecular weight:1446.65
  • BChE-IN-10

    CAS:
    <p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>
    Formula:C23H20O5
    Color and Shape:Solid
    Molecular weight:376.4
  • Kynuramine

    CAS:
    <p>Kynuramine is an aromatic ketone containing the aniline structure.</p>
    Formula:C9H12N2O
    Color and Shape:Solid
    Molecular weight:164.20
  • MGS0274

    CAS:
    <p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>
    Formula:C21H32FNO7
    Color and Shape:Solid
    Molecular weight:429.485
  • Anti-inflammatory agent 52


    <p>Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29</p>
    Formula:C24H21ClN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.95
  • Echimidine N-oxide

    CAS:
    <p>Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.</p>
    Formula:C20H31NO8
    Color and Shape:Solid
    Molecular weight:413.467
  • COX-2-IN-31


    <p>COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).</p>
    Formula:C17H16N6O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.41
  • Dual AChE-MAO B-IN-3


    <p>Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.</p>
    Formula:C30H26F3NO3
    Color and Shape:Solid
    Molecular weight:505.53
  • Melatonin-Tamoxifen Conjugate


    <p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>
    Formula:C47H58N4O4
    Color and Shape:Solid
    Molecular weight:742.99
  • Methalthiazide

    CAS:
    <p>Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.</p>
    Formula:C12H16ClN3O4S3
    Color and Shape:Solid
    Molecular weight:397.92
  • PZ-1922


    <p>PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.</p>
    Purity:98%
    Color and Shape:Odour Solid
  • MmTx2 toxin


    <p>MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.</p>
    Formula:C295H450N94O97S10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:7185.95
  • Fasciculic acid C

    CAS:
    <p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>
    Formula:C38H63NO11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:709.91
  • Lysyl hydroxylase 2-IN-2


    <p>Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.</p>
    Formula:C19H21N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:323.39
  • β-Amyloid (22-35)

    CAS:
    <p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>
    Formula:C59H102N16O21S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1403.62
  • NMDA receptor antagonist 6


    <p>NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective</p>
    Formula:C25H23NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:369.46
  • TB-11

    CAS:
    <p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>
    Formula:C52H78N8O12
    Color and Shape:Solid
    Molecular weight:1007.22
  • Guanylyl Imidodiphosphate (lithium salt)

    CAS:
    <p>Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.</p>
    Formula:C10H13Li4N6O13P3
    Color and Shape:Solid
    Molecular weight:545.93
  • Aminoacetone hydrochloride

    CAS:
    <p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>
    Formula:C3H8ClNO
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:109.56
  • sabcomeline

    CAS:
    <p>Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.</p>
    Formula:C10H15N3O
    Color and Shape:Solid
    Molecular weight:193.25
  • 2,3-Dehydrosilybin A

    CAS:
    <p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>
    Formula:C25H20O10
    Color and Shape:Solid
    Molecular weight:480.425
  • AChE/BChE-IN-26


    <p>AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.</p>
    Color and Shape:Odour Solid
  • BChE-IN-39


    <p>BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.</p>
    Formula:C29H23ClFN3O3
    Color and Shape:Solid
    Molecular weight:515.963
  • AChE-IN-4


    <p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>
    Formula:C32H25BrN6O4S
    Color and Shape:Solid
    Molecular weight:669.55
  • Isograndifoliol

    CAS:
    <p>Isograndifoliol: BChE inhibitor (IC50=0.9μM), weaker AChE inhibitor (IC50=342.9μM), with vasorelaxant and anti-tumor properties.</p>
    Formula:C19H26O3
    Color and Shape:Solid
    Molecular weight:302.41
  • NNC 11-1607

    CAS:
    <p>NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.</p>
    Formula:C30H32N6O2S2
    Color and Shape:Solid
    Molecular weight:572.74
  • Tiaspirone hydrochloride

    CAS:
    <p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>
    Formula:C24H33ClN4O2S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:477.06
  • 12,14-Dichlorodehydroabietic acid

    CAS:
    <p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>
    Formula:C20H26Cl2O2
    Color and Shape:Solid
    Molecular weight:369.33
  • Bleformin A

    CAS:
    <p>Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.</p>
    Formula:C23H20O5
    Color and Shape:Solid
    Molecular weight:376.4
  • Suntinorexton

    CAS:
    <p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>
    Formula:C23H28F2N2O4S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:466.54
  • Osmanthuside B

    CAS:
    <p>Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.</p>
    Formula:C29H36O13
    Color and Shape:Solid
    Molecular weight:592.59
  • β-Amyloid (1-9)

    CAS:
    <p>This is an N-terminal fragment of beta amyloid.</p>
    Formula:C42H60N14O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1033.01
  • β-Amyloid (13-27)

    CAS:
    β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.
    Formula:C84H126N24O24
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1856.05
  • Neocarzinostatin

    CAS:
    <p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • β-Amyloid (1-15)

    CAS:
    <p>β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.</p>
    Formula:C78H107N25O27
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:1826.84
  • MAO-B-IN-36


    <p>MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.</p>
    Formula:C20H14O3
    Color and Shape:Solid
    Molecular weight:302.32
  • Isonaringin

    CAS:
    <p>Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.</p>
    Formula:C27H32O14
    Color and Shape:Solid
    Molecular weight:580.53
  • hAChE/hBuChE-IN-1


    <p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>
    Formula:C30H31FN2O3
    Color and Shape:Solid
    Molecular weight:486.577
  • AL 34662

    CAS:
    <p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>
    Formula:C10H13N3O
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:191.23
  • Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Formula:C22H27Cl3F3N3S
    Color and Shape:Solid
    Molecular weight:528.89
  • Asenapine citrate

    CAS:
    <p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>
    Formula:C23H24ClNO8
    Color and Shape:Solid
    Molecular weight:477.89
  • 4-Butyl-α-agarofuran

    CAS:
    <p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>
    Formula:C18H30O
    Color and Shape:Solid
    Molecular weight:262.43
  • (Iso)-Samixogrel

    CAS:
    <p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>
    Formula:C25H25ClN2O4S
    Purity:98.80%
    Color and Shape:Solid
    Molecular weight:484.99
  • AChE/MAO-B-IN-7


    <p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>
    Formula:C22H21N3O3
    Color and Shape:Solid
    Molecular weight:375.42
  • Br-PBTC

    CAS:
    <p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>
    Formula:C14H15BrN2OS
    Color and Shape:Solid
    Molecular weight:339.25
  • 5β-Cholanic acid

    CAS:
    <p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>
    Formula:C24H40O2
    Purity:98.91% - 99.89%
    Color and Shape:Soild
    Molecular weight:360.57
  • I2-IRs ligand-1


    <p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>
    Formula:C21H23ClFN2O4P
    Color and Shape:Solid
    Molecular weight:452.84
  • Riluzole-13C,15N2

    CAS:
    <p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>
    Formula:CC7H5F3OS15N2
    Color and Shape:Solid
    Molecular weight:237.18
  • Adatanserin hydrochloride

    CAS:
    <p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>
    Formula:C21H32ClN5O
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:405.96
  • Crenezumab

    CAS:
    <p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>
    Purity:97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)
    Color and Shape:Liquid
  • PD10


    <p>PD10 is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), exhibiting inhibitory potency at human AChE (hAChE IC50: 0.56 μM),</p>
    Formula:C23H21BrN2O4
    Color and Shape:Solid
    Molecular weight:469.33
  • PSEN1-IN-2


    <p>PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.</p>
    Formula:C20H18ClFN2O3S
    Color and Shape:Solid
    Molecular weight:420.88
  • Litoxetine HCl


    <p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>
    Formula:C16H20ClNO
    Purity:99.56% - 99.75%
    Color and Shape:Soild
    Molecular weight:277.79
  • Fezolamine

    CAS:
    <p>Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.</p>
    Formula:C20H23N3
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:305.42
  • RuBi-Nicotine

    CAS:
    <p>Nicotinic receptor agonist</p>
    Formula:C40H44Cl2N8Ru
    Purity:98%
    Color and Shape:Solid
    Molecular weight:808.81
  • Lu AF27139

    CAS:
    <p>Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.</p>
    Formula:C21H19ClF3N5O2S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:497.92
  • SQ-3


    <p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>
    Formula:C21H21FN2O
    Color and Shape:Solid
    Molecular weight:336.4
  • 2,6-DMA hydrochloride

    CAS:
    <p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>
    Formula:C11H18ClNO2
    Color and Shape:Solid
    Molecular weight:231.72
  • BSB

    CAS:
    <p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>
    Formula:C24H17BrO6
    Purity:95.53%
    Color and Shape:Solid
    Molecular weight:481.29
  • GABAA receptor modulator-4


    <p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>
    Formula:C15H17BrO4S
    Color and Shape:Solid
    Molecular weight:373.26
  • M 8218

    CAS:
    <p>M 8218 is a bioactive chemical.</p>
    Formula:C20H29NO2
    Color and Shape:Solid
    Molecular weight:315.45
  • β-Amyloid (11-22)

    CAS:
    <p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>
    Formula:C70H102N18O18
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1483.67
  • Trontinemab

    CAS:
    <p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>
    Purity:96.77% - 99%
    Color and Shape:Liquid
  • Substance P(1-4) Acetate


    <p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>
    Formula:C24H44N8O7
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:556.66
  • SKF-83566 hydrochloride

    CAS:
    <p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>
    Formula:C17H19BrClNO
    Purity:99.27%
    Color and Shape:Soild
    Molecular weight:368.69
  • Pyrazolam

    CAS:
    <p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>
    Formula:C16H12BrN5
    Color and Shape:Solid
    Molecular weight:354.2
  • α-Conotoxin imi

    CAS:
    <p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>
    Formula:C52H78N20O15S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1351.56
  • UCM 549

    CAS:
    <p>UCM 549 is a bioactive chemical.</p>
    Formula:C19H21NO2
    Color and Shape:Solid
    Molecular weight:295.38
  • Laniquidar TFA


    <p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>
    Formula:C39H37F3N4O5
    Purity:99.85%
    Color and Shape:Soild
    Molecular weight:698.73
  • mcK6A1


    <p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>
    Formula:C71H99N17O16
    Color and Shape:Solid
    Molecular weight:1446.65
  • Endosulfan I

    CAS:
    <p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>
    Formula:C9H6Cl6O3S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:406.93
  • Withasomniferolide B

    CAS:
    <p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>
    Formula:C28H36O4
    Color and Shape:Solid
    Molecular weight:436.58
  • OM99-2 TFA

    CAS:
    <p>OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.</p>
    Formula:C43H65F3N8O16
    Color and Shape:Solid
    Molecular weight:1007.028
  • Anticonvulsant agent 8


    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Formula:C15H11N5O
    Color and Shape:Solid
    Molecular weight:277.28
  • Anti-Amyloid β Antibody (scFv59)


    <p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>
    Color and Shape:Odour Liquid
  • BuChE-IN-16


    <p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>
    Formula:C16H22N2O3
    Color and Shape:Solid
    Molecular weight:290.36
  • isomer-Cilansetron

    CAS:
    <p>isomer-Cilansetron is an isomer of Cilansetron.</p>
    Formula:C20H21N3O
    Purity:99.92% - 99.96%
    Color and Shape:Soild
    Molecular weight:319.4