Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(939 products)
- ACK(1 products)
- AChR(575 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,945 products)
- BACE(36 products)
- Beta Amyloid(205 products)
- CaMK(69 products)
- Cyclooxygenase (COX) Inhibitors(561 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(297 products)
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Found 5398 products of "Neuroscience"
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M 8218
CAS:<p>M 8218 is a bioactive chemical.</p>Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.45β-Amyloid (11-22)
CAS:<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formula:C70H102N18O18Purity:98%Color and Shape:SolidMolecular weight:1483.67BChE-IN-40
<p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>Formula:C28H30N2O7Color and Shape:SolidMolecular weight:506.2053Desfesoterodine
CAS:<p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>Formula:C22H31NO2Purity:99.77%Color and Shape:SolidMolecular weight:341.49Litoxetine HCl
<p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>Formula:C16H20ClNOPurity:99.56% - 99.75%Color and Shape:SoildMolecular weight:277.79rac Desmethyl Citalopram Hydrochloride
CAS:<p>rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.</p>Formula:C19H20ClFN2OPurity:99.24%Color and Shape:SolidMolecular weight:346.83COX-1-IN-2
<p>COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.</p>Formula:C29H22FN3OSColor and Shape:SolidMolecular weight:479.574-P-PDOT
CAS:<p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>Formula:C19H21NOPurity:99.91%Color and Shape:SolidMolecular weight:279.38COX-2-IN-46
<p>COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.</p>Formula:C28H19F2N3SColor and Shape:SolidMolecular weight:467.53LBG20304
<p>LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 μM, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 μM, it displays minimal agonist activity in neuronal slices (rat).</p>Formula:C19H18N4O5Color and Shape:SolidMolecular weight:382.37NT 13 acetate
<p>NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.</p>Formula:C20H34N4O9Purity:98%Color and Shape:SolidMolecular weight:474.51(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Formula:C6H11NO2Color and Shape:SolidMolecular weight:129.16BTMPS
CAS:<p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>Formula:C28H52N2O4Purity:98.1%Color and Shape:SolidMolecular weight:480.72MGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15Oxatomide
CAS:<p>Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).</p>Formula:C27H30N4OPurity:98.82% - 99.72%Color and Shape:White PowderMolecular weight:426.555-AAM-2-CP
CAS:<p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>Formula:C8H9ClN2OPurity:99.58%Color and Shape:SolidMolecular weight:184.62Tiflucarbine
CAS:<p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>Formula:C16H17FN2SPurity:>99.99%Color and Shape:SolidMolecular weight:288.38COX-2-IN-34
CAS:<p>COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.</p>Formula:C13H11NO4Purity:98.08%Color and Shape:SoildMolecular weight:245.235-HT2A receptor agonist-5
CAS:<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5SIB 1553A
CAS:<p>SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.</p>Formula:C13H19NOSPurity:99.79%Color and Shape:SoildMolecular weight:237.36Duloxetine D3 hydrochloride
CAS:<p>Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.</p>Formula:C18H20ClNOSPurity:98%Color and Shape:SolidMolecular weight:336.89Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Formula:C24H30N4O5Purity:99.85%Color and Shape:SolidMolecular weight:454.52Imipramine N-oxide
CAS:<p>Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.</p>Formula:C19H24N2OPurity:99.80%Color and Shape:SolidMolecular weight:296.41Zalospirone
CAS:<p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>Formula:C24H29N5O2Purity:98.41% - 99.82%Color and Shape:SolidMolecular weight:419.52Tropicamide
CAS:<p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>Formula:C17H20N2O2Purity:99.78% - 99.94%Color and Shape:White PowderMolecular weight:284.35Rapastinel acetate
CAS:<p>Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.</p>Formula:C20H35N5O8Purity:99.6%Color and Shape:SoildMolecular weight:473.52Davunetide acetate
<p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>Formula:C38H64N10O14Purity:99.52% - 99.78%Color and Shape:SolidMolecular weight:884.97bPiDDB
CAS:<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Formula:C24H38Br2N2Purity:98.72%Color and Shape:SolidMolecular weight:514.38BChE-IN-12
CAS:<p>BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.</p>Formula:C31H30O5Color and Shape:SolidMolecular weight:482.57JNJ-67569762
CAS:<p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>Formula:C22H22F4N4O5SColor and Shape:SolidMolecular weight:530.49Soclenicant
CAS:<p>Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability</p>Formula:C24H26N4O3Purity:99.57%Color and Shape:SoildMolecular weight:418.49(Iso)-Samixogrel
CAS:<p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>Formula:C25H25ClN2O4SPurity:98.80%Color and Shape:SolidMolecular weight:484.99AChE/BChE-IN-25
<p>AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.</p>Formula:C21H24ClN3O2Color and Shape:SolidMolecular weight:385.89G923-0271
CAS:<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Formula:C28H23FN4OColor and Shape:SolidMolecular weight:450.514-hydroxy DiPT hydrochloride
CAS:<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Formula:C16H25ClN2OColor and Shape:SolidMolecular weight:296.842-APB hydrochloride
CAS:<p>2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.</p>Formula:C11H14ClNOColor and Shape:SolidMolecular weight:211.69Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Formula:C47H58N4O4Color and Shape:SolidMolecular weight:742.99Rilmazolam
CAS:<p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>Formula:C19H15Cl2N5OColor and Shape:SolidMolecular weight:400.267-Methyl DMT
CAS:<p>7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.</p>Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Triazolomethylindole-3-acetic acid
CAS:<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.26Methamnetamine hydrochloride
CAS:<p>Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.</p>Formula:C14H18ClNColor and Shape:SolidMolecular weight:235.75MAO-B-IN-37
CAS:<p>MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.</p>Formula:C14H12FN3O3Color and Shape:SolidMolecular weight:289.266-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Formula:C14H19FN2Color and Shape:SolidMolecular weight:234.3125E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.89Argiotoxin 636
CAS:<p>Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.</p>Formula:C29H52N10O6Color and Shape:SolidMolecular weight:636.795-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.3225N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Formula:C18H23ClN2O5Color and Shape:SolidMolecular weight:382.84Desalkylgidazepam
CAS:<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Formula:C15H11BrN2OColor and Shape:SolidMolecular weight:315.174-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Formula:C12H18BrNO2Color and Shape:SolidMolecular weight:288.18DOPR hydrochloride
CAS:<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Formula:C14H24ClNO2Color and Shape:SolidMolecular weight:273.8Cinazepam
CAS:<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Formula:C19H14BrClN2O5Color and Shape:SolidMolecular weight:465.68p-Xylene bis(pyridinium bromide)
CAS:<p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>Formula:C18H18Br2N2Color and Shape:SolidMolecular weight:422.16TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.36TC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Formula:C12H17N3Purity:99.33%Color and Shape:SolidMolecular weight:203.28Profenofos
CAS:<p>Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.</p>Formula:C11H15BrClO3PSPurity:97.04% - 97.24%Color and Shape:SolidMolecular weight:373.63Serazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Formula:C22H23N3O2Purity:98.71% - 99.57%Color and Shape:SolidMolecular weight:361.44AChE/BuChE-IN-4
CAS:<p>AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.</p>Formula:C17H23N5Purity:99.89%Color and Shape:SoildMolecular weight:297.4COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Formula:C22H19NO2S2Purity:98%Color and Shape:SolidMolecular weight:393.52Tranylcypromine
CAS:<p>Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.</p>Formula:C9H11NPurity:98%Color and Shape:SolidMolecular weight:133.19JPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Formula:C22H43NO4Purity:98%Color and Shape:SolidMolecular weight:385.58mGluR3 modulator-1
CAS:<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Formula:C16H21N3OPurity:98.99%Color and Shape:SolidMolecular weight:271.36Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Formula:C24H22N2O4SPurity:98%Color and Shape:SolidMolecular weight:434.51hAChE-IN-3
<p>hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,</p>Formula:C30H24ClN3O5Purity:98%Color and Shape:SolidMolecular weight:541.98MAO-B-IN-24
<p>MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM.</p>Formula:C20H18N2OPurity:98%Color and Shape:SolidMolecular weight:302.37KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formula:C22H12F3N5Na2O7Purity:97.27%Color and Shape:SoildMolecular weight:561.33Pozanicline hydrochloride
<p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>Formula:C11H17ClN2OPurity:97.13% - 99.81%Color and Shape:SolidMolecular weight:228.725H-Pyrido[4,3-b]indole
CAS:<p>5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.</p>Formula:C11H8N2Purity:99.6%Color and Shape:SolidMolecular weight:168.2GABA receptor Antagonist 1
<p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>Purity:98%Color and Shape:Odour SolidMAOA-IN-1
<p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>Formula:C13H16Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:303.18Laniquidar TFA
<p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>Formula:C39H37F3N4O5Purity:99.85%Color and Shape:SoildMolecular weight:698.73IHC3
<p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>Formula:C17H12FN3OPurity:98%Color and Shape:SolidMolecular weight:293.3NMDA receptor antagonist 7
<p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>Formula:C22H27N3OPurity:98%Color and Shape:SolidMolecular weight:349.47Paynantheine
CAS:<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48AChE-IN-45
<p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>Color and Shape:Odour SolidCalmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Formula:C105H189N31O26SPurity:96.7%Color and Shape:SolidMolecular weight:2333.88Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formula:C9H6Cl6O3SPurity:99.86%Color and Shape:SolidMolecular weight:406.93(R)-Citalopram oxalate
CAS:<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formula:C22H23FN2O5Purity:99.76%Color and Shape:White SolidMolecular weight:414.43Lysyl hydroxylase 2-IN-1
<p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>Formula:C18H18N2O3Purity:98%Color and Shape:SolidMolecular weight:310.35FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
<p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>Formula:C227H330N58O66S2Color and Shape:SolidMolecular weight:4991.53MAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Formula:C23H20ClF2N3Purity:98%Color and Shape:SolidMolecular weight:411.87CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Formula:C54H58Cl2N10O11Purity:98%Color and Shape:SolidMolecular weight:1094(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Formula:C203H311N55O62SColor and Shape:SolidMolecular weight:4546.04AChE/Aβ-IN-6
<p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>Color and Shape:Odour SolidAtagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Formula:C215H326F3N57O64S2Color and Shape:SolidMolecular weight:4854.36MmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Formula:C295H455N95O97S10Purity:98%Color and Shape:SolidMolecular weight:7205Sulamserod
CAS:<p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>Formula:C19H28ClN3O5SPurity:98.76%Color and Shape:SolidMolecular weight:445.96LY836
<p>LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons.</p>Purity:98%Color and Shape:Odour SolidSubstance P(1-4) Acetate
<p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>Formula:C24H44N8O7Purity:99.84%Color and Shape:SolidMolecular weight:556.66Neuroprotective Compound Library
<p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidRA306
<p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>Color and Shape:Odour SolidOXA(17-33)
CAS:<p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>Formula:C79H125N23O22Purity:98%Color and Shape:SolidMolecular weight:1749mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formula:C71H99N17O16Color and Shape:SolidMolecular weight:1446.65BuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Color and Shape:Odour Solid(Glu20)-Amyloid β-Protein (1-42)
CAS:<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formula:C199H309N55O62SColor and Shape:SolidMolecular weight:4495.98Cloxacepride
CAS:<p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>Formula:C22H27Cl2N3O4Purity:99.62%Color and Shape:SolidMolecular weight:468.37Acetyl-Tau Peptide (273-284) amide
CAS:<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Formula:C64H116N18O17Color and Shape:SolidMolecular weight:1409.72N-Ethyl-N-(3-pyridylmethyl)amine
CAS:<p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>Formula:C8H12N2Purity:99.65%Color and Shape:SolidMolecular weight:136.195-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Formula:C17H22F2N6OPurity:98%Color and Shape:SolidMolecular weight:364.39Rasagiline 13C3 mesylate racemic
CAS:<p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>Formula:C13H17NO3SPurity:98%Color and Shape:SolidMolecular weight:270.32
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