Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(647 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,025 products)
- BACE(37 products)
- Beta Amyloid(230 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(602 products)
- Dopamine Receptor(445 products)
- GABA Receptor(373 products)
- Gamma-secretase(62 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5639 products of "Neuroscience"
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SB-221284
CAS:5-HT2C/2B receptor antagonistFormula:C16H14F3N3OSPurity:98%Color and Shape:SolidMolecular weight:353.36CCD-3693
CAS:CCD-3693 is a gamma-aminobutyric acid (GABA) receptor agonist.Formula:C21H31F3O2Purity:98%Color and Shape:SolidMolecular weight:372.46LY 125180
CAS:LY 125180 is a serotonin antagonist.Formula:C18H24ClNOPurity:98%Color and Shape:SolidMolecular weight:305.84ML375
CAS:ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).Formula:C23H15ClF2N2O2Color and Shape:SolidMolecular weight:424.83Rapacuronium bromide
CAS:Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.Formula:C37H61BrN2O4Purity:98%Color and Shape:SolidMolecular weight:677.8LY 334370 hydrochloride
CAS:5-HT1F receptor agonistFormula:C21H23ClFN3OPurity:98%Color and Shape:SolidMolecular weight:387.88FK960
CAS:FK962 boosts somatostatin, enhances cognition, and raises synaptic density in rat hippocampus.Formula:C13H16FN3O2Purity:98%Color and Shape:SolidMolecular weight:265.28Dimethyl-W84 (dibromide)
CAS:Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.Formula:C34H48Br2N4O4Color and Shape:SolidMolecular weight:736.59Pivalylbenzhydrazine
CAS:Pivhydrazine: strong MAO inhibitor, stunts rat cartilage growth, used in depression research.Formula:C12H18N2OColor and Shape:SolidMolecular weight:206.28Aβ42-IN-1 free base
CAS:Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091Formula:C29H26N4O2Purity:98%Color and Shape:SolidMolecular weight:462.54VU 6008667
CAS:VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).Formula:C24H17ClF2N2O2Purity:98%Color and Shape:SolidMolecular weight:438.85Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Formula:C25H27FN2O3Color and Shape:SolidMolecular weight:422.49PAT-1251 Hydrochloride
CAS:PAT-1251 Hydrochloride: Potent, selective, oral LOXL2 inhibitor; IC50s - 0.71 μM (hLOXL2), 1.17 μM (hLOXL3).Formula:C18H18ClF4N3O3Purity:98%Color and Shape:SolidMolecular weight:435.8WAY 629 hydrochloride
CAS:5-HT2C agonistFormula:C15H19ClN2Purity:98%Color and Shape:SolidMolecular weight:262.78Alosetron ((Z)-2-butenedioate)
CAS:Alosetron (GR 68755) (Z)-2-butenedioate is a Serotonin 5HT3-receptor antagonist that is used in the treatment of irritable bowel syndrome.Formula:C21H22N4O5Purity:98%Color and Shape:SolidMolecular weight:410.42VU 0360223
CAS:VU 0360223 is a negative allosteric modulator of mGlu5.Formula:C15H9FN2SPurity:98%Color and Shape:SolidMolecular weight:268.31Oxetorone fumarate
CAS:Oxetorone fumarate is a non-selective, orally active antagonist of serotonin and 5-HT receptors,used for migraine treatment.Formula:C25H25NO6Purity:99.809%Color and Shape:SolidMolecular weight:435.48Bibn 99
CAS:Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.Formula:C31H42ClN5O3Color and Shape:SolidMolecular weight:568.15β-CCB
CAS:benzodiazepine receptor ligandFormula:C16H16N2O2Purity:98%Color and Shape:SolidMolecular weight:268.31L-AP4 monohydrate
CAS:L-AP4 (L-APB) is a group III mGluR agonist with EC50s: 0.13μM (mGlu4), 0.29μM (mGlu8), 1.0μM (mGlu6), 249μM (mGlu7).Formula:C4H12NO6PColor and Shape:SolidMolecular weight:201.115RJR 2429 dihydrochloride
CAS:nAChR agonist that displays selectivity for α4β2Formula:C12H18Cl2N2Purity:98%Color and Shape:SolidMolecular weight:261.19LY 344864 hydrochloride
CAS:LY 344864 hydrochloride is a selective receptor agonist with an affinity of 6 nM (Ki) at the 5-HT1F receptor.Formula:C21H23ClFN3OColor and Shape:SolidMolecular weight:387.88CP-601927
CAS:CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.23BChE-IN-15
BChE-IN-15 is a compound characterized as a pseudo-irreversible, covalent inhibitor of butyrylcholinesterase (BChE), demonstrating potent activity with anFormula:C22H33N3O2Color and Shape:SolidMolecular weight:371.52Rivanicline
CAS:Rivanicline is a selective α4β2 nicotinic receptor agonist (Ki=26 nM), with >1,000x less affinity for α7 receptors.Formula:C10H14N2Purity:98%Color and Shape:SolidMolecular weight:162.23RR-11a analog
CAS:RR-11a (aza-peptide) inhibits asparaginyl endopeptidase: IC50 - 4.5 nM (T. Vaginalis, I. ricinus), 31 nM (S. mansoni).Formula:C22H29N5O8Purity:98.80%Color and Shape:SolidMolecular weight:491.49Ref: TM-T12770
1mg152.00€5mg364.00€1mL*10mM (DMSO)394.00€10mg565.00€25mg1,044.00€50mg1,773.00€100mg2,602.00€BisQ
CAS:BisQ is an agonist of photochromic. It used for the muscle-type nAChR.Formula:C20H30IN4Purity:98%Color and Shape:SolidMolecular weight:453.392EMD 386088 hydrochloride
CAS:EMD 386088 hydrochloride is a 5-HT6 receptor agonist.Formula:C14H16Cl2N2Purity:98%Color and Shape:SolidMolecular weight:283.2CGS-12066 maleate salt
CAS:CGS-12066 maleate salt is an agonist of 5-HT1B serotonin receptor.Formula:C21H21F3N4O4Color and Shape:SolidMolecular weight:450.41TAK-070
CAS:TAK-070 is a non-competitive inhibitor of BACE1.Formula:C27H31NOPurity:98%Color and Shape:SolidMolecular weight:385.54Org37684
CAS:5-HT2 receptors agonistFormula:C14H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:269.77VU0366248
CAS:VU0366248 is a mGlu5 negative allosteric modulator.Formula:C14H7ClF2N2OPurity:98%Color and Shape:SolidMolecular weight:292.67BGT1-IN-9
CAS:BGT1-IN-9 is an M1 muscarinic agonist.Formula:C5H10ClN3O2Color and Shape:SolidMolecular weight:179.605GABAA receptor agent 5
CAS:Compound 018 is a potent γ-GABAAR antagonist, Ki of 0.020 μM, with low membrane permeability.Formula:C21H25N3O2SPurity:99.39%Color and Shape:SolidMolecular weight:383.51p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H29Cl2FN4O2Purity:99.55%Color and Shape:SolidMolecular weight:507.43PF-3246799
CAS:PF-3246799 is an effective and selective agonist of the 5-HT2C receptor.Formula:C15H17N3Purity:98%Color and Shape:SolidMolecular weight:239.32Amitriptylinoxide
CAS:Amitriptylinoxide is an antidepressant.Formula:C20H23NOPurity:98%Color and Shape:SolidMolecular weight:293.4Obidoxime dichloride
CAS:Obidoxime dichloride is an antidote for organophosphate poisoning that enhances the positive inotropic effect of phosphamidon on isolated working rat hearts.Formula:C14H16Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:359.21BGC 20-761
CAS:BGC20-761: selective 5-HT6/Dopamine antagonist; enhances memory, potential antipsychotic. K i - 5-HT6: 20 nM, 5-HT2A: 69 nM, D2: 140 nM.Formula:C19H22N2OColor and Shape:SolidMolecular weight:294.39Way 100289
CAS:Way 100289 is a selective 5-HT3 receptor antagonist.Formula:C20H27N3O3Color and Shape:SolidMolecular weight:357.453,3'-Difluorobenzaldazine
CAS:allosteric potentiator of mGlu5Formula:C14H10F2N2Purity:98%Color and Shape:SolidMolecular weight:244.24CGP 46381
CAS:CGP 46381 is a GABAB receptor antagonist.Formula:C10H22NO2PPurity:98%Color and Shape:White SolidMolecular weight:219.26Sofiniclin
CAS:Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).Formula:C10H11Cl2N3Purity:98%Color and Shape:SolidMolecular weight:244.12(RS)-MCPG disodium salt
CAS:group I/group II metabotropic glutamate receptor antagonistFormula:C10H11NNaO4Purity:98%Color and Shape:SolidMolecular weight:232.19GlyT1 Inhibitor 1
CAS:GlyT1 Inhibitor 1 is a selective and potent GlyT1 inhibitor, inhibiting rGlyT1, used in research on neurological disorders.Formula:C22H21N5O2Color and Shape:SolidMolecular weight:387.43A-794282
CAS:A-794282 is a selective antagonist of mGluR1.Formula:C19H18N4OSPurity:99.87%Color and Shape:SolidMolecular weight:350.44Ro 67-4853
CAS:Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).Formula:C19H19NO4Purity:98.57%Color and Shape:SolidMolecular weight:325.36Masupirdine mesylate
CAS:Masupirdine mesylate (SUVN-502 mesylate) is a 5-HT6 receptor antagonist.Masupirdine mesylate is used to study neurological disorders such as Alzheimer's diseaseFormula:C23H32BrN3O9S3Purity:99.57%Color and Shape:SolidMolecular weight:670.61Zimelidine dihydrochloride
CAS:5-HT re-uptake inhibitorFormula:C16H18BrClN2Purity:98%Color and Shape:SolidMolecular weight:353.69GSK-215083
CAS:GSK-215083: a PET quinoline-based 5-HT6 antagonist radioligand, binds 5HT6 in striatum and 5HT2A in frontal cortex.Formula:C20H20FN3O2SColor and Shape:SolidMolecular weight:385.46(+)-Donepezil
CAS:(+)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.Formula:C24H29NO3Color and Shape:SolidMolecular weight:379.49Blonanserin HCl
CAS:Blonanserin is an antagonist of dopamine-D2 and serotonin-S2.Formula:C23H32Cl2FN3Purity:98%Color and Shape:SolidMolecular weight:440.42ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Formula:C20H14F5N3O2SColor and Shape:SolidMolecular weight:455.4mGluR2 modulator 1
CAS:Potent mGluR2 modulator 1 crosses blood-brain barrier, EC50: 0.03 μM, useful for psychiatric research.Formula:C21H20F3N3O3Color and Shape:SolidMolecular weight:419.4RO4988546
CAS:RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.Formula:C21H10F6N4O3SPurity:98%Color and Shape:SolidMolecular weight:512.38Isamoltane hemifumarate
CAS:5-HT1B antagonistFormula:C16H22N202C4H404Purity:98%Color and Shape:SolidMolecular weight:332.4LSN2814617
CAS:LSN2814617: oral, brain-penetrant mGlu5 PAM, EC50 = 52 nM (human), 42 nM (rat). Promotes wakefulness, useful in schizophrenia study.Formula:C18H20FN5OPurity:98%Color and Shape:SolidMolecular weight:341.38UCSF648
CAS:UCSF648 (Compound 5A6-48) weakly activates MTNR1A and ADRA2A. UCSF648 is a chemical probe for the serotonin receptor 5-HT 5A [1].Formula:C15H19ClN2O2SColor and Shape:SolidMolecular weight:326.84Milameline
CAS:Milameline is a muscarinic receptor agonist that improves cognition.Formula:C8H14N2OColor and Shape:SolidMolecular weight:154.21CP-409092 hydrochloride
CAS:CP-409092 hydrochloride is a partial agonist of the GABAA receptor with anti-anxiety activity.Formula:C17H20ClN3O2Color and Shape:SolidMolecular weight:333.81Rispenzepine
CAS:Rispenzepine, a novel mAChRs M1/M3 antagonist, treats immune, infections, and respiratory issues.Formula:C19H20N4O2Purity:98%Color and Shape:SolidMolecular weight:336.39CK59
CAS:CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.Formula:C21H37N7O3Purity:98%Color and Shape:SolidMolecular weight:435.56(S)-4C3HPG
CAS:group I mGlu1a/1a receptor antagonist and mGluR2 agonistFormula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17PF-03463275
CAS:PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS
Formula:C19H22ClFN4OPurity:99.86%Color and Shape:SolidMolecular weight:376.86Arbaclofen placarbil
CAS:Arbaclofen placarbil is a GABA(B) receptor agonist with better ADMET than R-baclofen, reducing postprandial reflux in GERD.Formula:C19H26ClNO6Color and Shape:SolidMolecular weight:399.87TC-E 5006
CAS:γ-secretase modulatorFormula:C29H29F4NO2Purity:98%Color and Shape:SolidMolecular weight:499.54LY 344864 S-enantiomer
CAS:LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42Ethyl dirazepate
CAS:Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.Formula:C18H14Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:377.22VU0364289
CAS:VU0364289 is a positive allosteric modulator of mGlu5.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4Revatropate
CAS:Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.Formula:C19H27NO4SColor and Shape:SolidMolecular weight:365.49Bopindolol fumarate
CAS:Bopindolol fumarate: non-selective β1/β2-adrenoceptor blocker, partial agonist, low β3 affinity, treats hypertension.Formula:C27H32N2O7Color and Shape:SolidMolecular weight:496.56AChE/BChE/BACE-1-IN-2
CAS:Compound 4o, an oral AChE, BChE, & BACE-1 inhibitor, has potent antioxidant, neuroprotective qualities & breaks down Aβ aggregates.Formula:C18H20F2N2Color and Shape:SolidMolecular weight:302.36U-7524
CAS:U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.Formula:C2H5NO3Color and Shape:SolidMolecular weight:91.075-HT6/5-HT2A receptor ligand-1
CAS:Compound 33 is a dual 5-HT6/5-HT2A antagonist with Ki values of 2 nM and 11 nM, respectively, useful in neuro/psychiatric research.Formula:C21H19FN2O2Color and Shape:SolidMolecular weight:350.39Y 23684
CAS:Y-23684 is an anxiolytic drug with a novel chemical structure. It has similar effects to benzodiazepine drugs and is classed as a nonbenzodiazepine anxiolytic.Formula:C18H13ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:356.83Tarafenacin
CAS:Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C21H20F4N2O2Purity:98%Color and Shape:SolidMolecular weight:408.39AChE-IN-7
CAS:AChE-IN-7 inhibits eeAChE (IC50: 0.045μM), eeBuChE (19.68μM), crosses the blood-brain barrier, safe, with good pharmacokinetics and 55.5% bioavailability.Formula:C26H28N2O2Color and Shape:SolidMolecular weight:400.51RS 64459-193
CAS:RS 64459-193 has a high affinity for the 5-HT1A binding site.Formula:C26H36Cl2N2O2Color and Shape:SolidMolecular weight:479.48S-(+)-Mecamylamine hydrochloride
CAS:Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.Formula:C11H22ClNColor and Shape:SolidMolecular weight:203.75Cyprodenate
CAS:Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.Formula:C13H25NO2Color and Shape:SolidMolecular weight:227.34Ref: TM-T72977
1mg37.00€5mg72.00€1mL*10mM (DMSO)79.00€10mg99.00€25mg169.00€50mg229.00€100mg320.00€200mg479.00€ACPT-I
CAS:Agonist for group III mGlu receptorsFormula:C8H11NO6Purity:98%Color and Shape:SolidMolecular weight:217.18Mebanazine
CAS:Mebanazine, a potent monoamine oxidase (MAO) inhibitor, is utilized in depression research.Formula:C8H12N2Color and Shape:SolidMolecular weight:136.19(S)-Venlafaxine
CAS:(S)-Venlafaxine: oral antidepressant, potent dual serotonin/norepinephrine reuptake inhibitor.Formula:C17H27NO2Color and Shape:SolidMolecular weight:277.4DS1
CAS:DS1 is a GABAA receptor agonist which can stimulate gonadotropin subunit gene expression in mouse.Formula:C18H10Br2ClN3OSColor and Shape:SolidMolecular weight:511.62(R)-Viloxazine Hydrochloride
CAS:(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine.Formula:C13H20ClNO3Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:273.76Ref: TM-T22413
1mg52.00€1mL*10mM (DMSO)101.00€5mg111.00€10mg162.00€25mg235.00€50mg330.00€100mg452.00€200mg607.00€Iloperidone hydrochloride
CAS:Iloperidone hydrochloride is a D(2)/5-HT(2) receptor antagonist. It is also an atypical antipsychotic for the treatment of schizophrenia symptoms.Formula:C24H28ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:462.95JNJ-46356479
CAS:JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.Formula:C22H22F5N5Color and Shape:SolidMolecular weight:451.44SB 258719 hydrochloride
CAS:Selective 5-HT7 receptor antagonistFormula:C18H31ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:374.97Alaproclate hydrochloride, (S)-
CAS:Alaproclate hydrochloride, (S)- is a selective inhibitor of serotonin reuptake.Formula:C13H19Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:292.2OPC-14523 free base
CAS:OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.Formula:C23H28ClN3O2Purity:98%Color and Shape:SolidMolecular weight:413.94NFPS
CAS:NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion.Formula:C24H24FNO3Purity:98%Color and Shape:SolidMolecular weight:393.45LY320135
CAS:CB1 receptor antagonist/inverse agonistFormula:C24H17NO4Purity:98%Color and Shape:SolidMolecular weight:383.4Alaproclate
CAS:Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia.Formula:C13H18ClNO2Purity:98.29% - 98.64%Color and Shape:SolidMolecular weight:255.74CV-159
CAS:CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.Formula:C31H34N4O7Purity:98%Color and Shape:SolidMolecular weight:574.62Cimoxatone
CAS:Cimoxatone is used as a Monoamine Oxidase Inhibitor.Formula:C19H18N2O4Color and Shape:SolidMolecular weight:338.36YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFormula:C26H16Br2ClN3Color and Shape:SolidMolecular weight:565.69Org-12962 hydrochloride
CAS:Org-12962 hydrochloride is a 5-HT2C receptor agonist.Formula:C10H12Cl2F3N3Purity:98%Color and Shape:SolidMolecular weight:302.12CP-601932
CAS:CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.233-Methyl-GABA
CAS:3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.Formula:C20H30N2O10S2Purity:98%Color and Shape:SolidMolecular weight:522.59OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Formula:C32H46N4O2Color and Shape:SolidMolecular weight:518.73
