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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • VU 0285683

    CAS:
    <p>VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.</p>
    Formula:C14H7FN4O
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:266.23
  • DA-6886

    CAS:
    <p>DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.</p>
    Formula:C19H28Cl2N6O2
    Purity:99.28% - 99.91%
    Color and Shape:Solid
    Molecular weight:443.37
  • AZD 9272

    CAS:
    <p>AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.</p>
    Formula:C14H6F2N4O
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:284.22
  • PF-03635659

    CAS:
    <p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>
    Formula:C28H32N2O3
    Purity:98.39% - 99.83%
    Color and Shape:Solid
    Molecular weight:444.57
  • Buntanetap

    CAS:
    <p>Buntanetap ((+)-Phenserine) is an inhibitor of TINAPs used in the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular disease</p>
    Formula:C20H23N3O2
    Purity:98.2%
    Color and Shape:Solid
    Molecular weight:337.42
  • Cianopramine

    CAS:
    <p>Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.</p>
    Formula:C20H23N3
    Purity:99.92% - 99.92%
    Color and Shape:Solid
    Molecular weight:305.42
  • Riluzole hydrochloride

    CAS:
    <p>Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).</p>
    Formula:C8H6ClF3N2OS
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:270.66
  • Alpidem

    CAS:
    <p>Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.</p>
    Formula:C21H23Cl2N3O
    Purity:99.56% - 99.97%
    Color and Shape:White To Off-White Solid
    Molecular weight:404.33
  • PNU-282987 free base

    CAS:
    <p>PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.</p>
    Formula:C14H17ClN2O
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:264.75
  • CP-810123

    CAS:
    <p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>
    Formula:C14H18N4O
    Purity:98.63% - 99.60%
    Color and Shape:Solid
    Molecular weight:258.32
  • Litoxetine

    CAS:
    <p>Litoxetine: a selective 5-HT inhibitor &amp; 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.</p>
    Formula:C16H19NO
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:241.33
  • Teniloxazine

    CAS:
    <p>Teniloxazine is an orally available antidepressant compound with anti-hypoxic properties.</p>
    Formula:C16H19NO2S
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:289.39
  • Cyamemazine

    CAS:
    <p>Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.</p>
    Formula:C19H21N3S
    Purity:97.01%
    Color and Shape:Solid
    Molecular weight:323.46
  • PPI-1019

    CAS:
    <p>PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).</p>
    Formula:C36H54N6O5
    Purity:95.16% - 98.16%
    Color and Shape:Solid
    Molecular weight:650.85
  • TAK-137

    CAS:
    <p>TAK-137 is an AMPA receptor enhancer with antidepressant effects. TAK-137 has the ability to improve cognition and could be used to study schizophrenia.</p>
    Formula:C19H16N2O3S
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:352.41
  • Tribendimidine

    CAS:
    <p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>
    Formula:C28H32N6
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:452.59
  • Fananserin

    CAS:
    <p>Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).</p>
    Formula:C23H24FN3O2S
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:425.52
  • Suriclone

    CAS:
    <p>Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.</p>
    Formula:C20H20ClN5O3S2
    Purity:99.21% - 99.73%
    Color and Shape:Solid
    Molecular weight:477.99
  • Oxotremorine M iodide

    CAS:
    <p>Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.</p>
    Formula:C11H19IN2O
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:322.19
  • Ezeprogind disulfate

    CAS:
    <p>Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.</p>
    Formula:C25H48N6O8S2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:624.81
  • Gavestinel sodium

    CAS:
    <p>Gavestinel (GV 150526): potent, selective oral NMDA antagonist; binds glycine site, pKi 8.5; studied for acute ischemic stroke.</p>
    Formula:C18H11Cl2N2NaO3
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:397.19
  • CT-179

    CAS:
    <p>CT-179 is a potent and selective inhibitor of OLIG2, reduces tumor cell proliferation and induces apoptosis, fpr medulloblastoma and glioblastoma.</p>
    Formula:C17H22Cl2N6O
    Purity:98.67%
    Color and Shape:Solid
    Molecular weight:397.3
  • PHA 543613

    CAS:
    <p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>
    Formula:C15H17N3O2
    Purity:99.43% - 99.96%
    Color and Shape:Solid
    Molecular weight:271.31
  • Femoxetine hydrochloride

    CAS:
    <p>Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.</p>
    Formula:C20H26ClNO2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:347.88
  • Lirequinil

    CAS:
    <p>Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.</p>
    Formula:C26H25ClN2O3
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:448.94
  • MNI 137

    CAS:
    <p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>
    Formula:C15H9BrN4O
    Purity:97.49%
    Color and Shape:Solid
    Molecular weight:341.16
  • CP 96021

    CAS:
    <p>"CP 96021 is an antagonist of 5-HT1/2 receptors, with anti-inflammatory and anti-ulcer effects for treating GI tract and asthma."</p>
    Formula:C29H21FN4OS
    Purity:97.81% - 99.62%
    Color and Shape:Soild
    Molecular weight:492.57
  • NNC 05-711

    CAS:
    <p>NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.</p>
    Formula:C21H23ClN2O3
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:386.87
  • Eltenac

    CAS:
    <p>Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.</p>
    Formula:C12H9Cl2NO2S
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:302.18
  • NS-2710

    CAS:
    <p>NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.</p>
    Formula:C22H20N4O
    Purity:99.7% - 99.82%
    Color and Shape:Solid
    Molecular weight:356.42
  • SPD-473 citrate

    CAS:
    <p>SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.</p>
    Formula:C23H31Cl2NO8S
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:552.47
  • amyloid P-IN-1

    CAS:
    <p>amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and</p>
    Formula:C30H44N2O14
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:656.68
  • Tedatioxetine

    CAS:
    <p>Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.</p>
    Formula:C18H21NS
    Purity:99.76% - >99.99%
    Color and Shape:Solid
    Molecular weight:283.43
  • Liafensine

    CAS:
    <p>Liafensine(BMS-820836): Selective inhibitor for serotonin, norepinephrine, dopamine reuptake; targets major depression, CNS disorders.</p>
    Formula:C24H22N4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:366.46
  • GSK233705

    CAS:
    <p>GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.</p>
    Formula:C24H29BrN2
    Purity:99.87% - 99.98%
    Color and Shape:Solid
    Molecular weight:425.4
  • DMCM hydrochloride

    CAS:
    <p>DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.</p>
    Formula:C17H19ClN2O4
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:350.8
  • Ru-32514

    CAS:
    <p>Ru-32514 is a benzodiazepine receptor agonist.</p>
    Formula:C18H17N3O2
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:307.35
  • Landipirdine

    CAS:
    <p>Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.</p>
    Formula:C18H19FN2O3S
    Purity:97.61% - 99.37%
    Color and Shape:Solid
    Molecular weight:362.42
  • NB001

    CAS:
    <p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>
    Formula:C12H20N6O
    Purity:99.69%
    Color and Shape:Off-White To Pale Pink Solid
    Molecular weight:264.33
  • LM-1685

    CAS:
    <p>LM-1685是一种有效且具有选择性的人单核细胞和全血中COX-2抑制剂,IC50分别为0.65 µM 和IC50 = 4.3 μM,是治疗炎症的潜在化合物。</p>
    Formula:C18H16ClNO4S
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:377.84
  • Otenzepad

    CAS:
    <p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>
    Formula:C24H31N5O2
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:421.54
  • Aβ-IN-1

    CAS:
    <p>Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Formula:C35H49N
    Purity:99.1%
    Color and Shape:Soild
    Molecular weight:483.77
  • ATC 0175 hydrochloride

    CAS:
    <p>ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective.</p>
    Formula:C23H26ClF2N5O
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:461.93
  • SB-215505

    CAS:
    <p>SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).</p>
    Formula:C19H16ClN3O
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:337.8
  • DSP-0565

    CAS:
    <p>DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.</p>
    Formula:C14H12FNO
    Purity:99.51% - 99.56%
    Color and Shape:Solid
    Molecular weight:229.25
  • PAT-1251

    CAS:
    <p>PAT-1251 is an inhibitor of LOXL2 with IC50s of 10, 0.12, and 0.16 μM for the mouse, rat, and dog and can be used in studies about fibrotic diseases.</p>
    Formula:C18H17F4N3O3
    Purity:97.27% - 98.46%
    Color and Shape:Solid
    Molecular weight:399.34
  • ELB-139

    CAS:
    <p>ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.</p>
    Formula:C14H16ClN3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:277.75
  • AMPA receptor antagonist-2

    CAS:
    <p>AMPA receptor antagonist-2 is an AMPA receptor antagonist.</p>
    Formula:C18H17N3O4
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:339.35
  • Quinupramine

    CAS:
    <p>Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.</p>
    Formula:C21H24N2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:304.43
  • MM 77 dihydrochloride

    CAS:
    <p>MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.</p>
    Formula:C19H29Cl2N3O3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:418.36
  • W-9 hydrochloride

    CAS:
    <p>W-9 hydrochloride is a calmodulin antagonist.</p>
    Formula:C16H22Cl2N2O2S
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:377.33
  • 5-HT6/7 antagonist 1

    CAS:
    <p>5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.</p>
    Formula:C22H20FN3O3
    Purity:98.78% - 99.26%
    Color and Shape:Solid
    Molecular weight:393.41
  • SB228357

    CAS:
    <p>SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.</p>
    Formula:C22H17F4N3O2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:431.38
  • 5-HT1A modulator 1

    CAS:
    <p>5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).</p>
    Formula:C21H25N3O2S
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:383.51
  • GR 46611

    CAS:
    <p>GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.</p>
    Formula:C23H27N3O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:377.48
  • Ricasetron

    CAS:
    <p>Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.</p>
    Formula:C19H27N3O
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:313.44
  • Progabide

    CAS:
    <p>Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.</p>
    Formula:C17H16ClFN2O2
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:334.77
  • Pimethixene maleate

    CAS:
    <p>Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.</p>
    Formula:C23H23NO4S
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:409.5
  • ADR-851 free base

    CAS:
    <p>ADR-851 free base is an antagonist of the HT3 receptor.</p>
    Formula:C14H18ClN3O2
    Purity:97.88% - 98.39%
    Color and Shape:Solid
    Molecular weight:295.77
  • 5-HT2 antagonist 1

    CAS:
    <p>5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.</p>
    Formula:C22H29FN4O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:400.49
  • GSK-1482160

    CAS:
    <p>GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity.</p>
    Formula:C14H14ClF3N2O2
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:334.72
  • 5-HT2 agonist-1 free base

    CAS:
    <p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>
    Formula:C19H22N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.39
  • Abaperidone

    CAS:
    <p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>
    Formula:C25H25FN2O5
    Purity:98.22%
    Color and Shape:Solid
    Molecular weight:452.47
  • COR659

    CAS:
    <p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>
    Formula:C16H16ClNO3S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:337.82
  • Pomaglumetad methionil hydrochloride

    CAS:
    <p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>
    Formula:C12H19ClN2O7S2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:402.87
  • VU0360172

    CAS:
    <p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>
    Formula:C18H15FN2O
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:294.32
  • Tiotropium Bromide hydrate

    CAS:
    <p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>
    Formula:C19H24BrNO5S2
    Purity:98.44% - 99.41%
    Color and Shape:Solid
    Molecular weight:490.43
  • Diproqualone

    CAS:
    <p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>
    Formula:C12H14N2O3
    Color and Shape:Solid
    Molecular weight:234.255
  • MAO-B-IN-19

    CAS:
    <p>MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].</p>
    Formula:C15H11FO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:242.25
  • GMA-839

    CAS:
    <p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>
    Formula:C21H31F3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:388.46
  • NCS-382 sodium

    CAS:
    <p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>
    Formula:C13H13NaO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:240.23
  • AMPA receptor modulator-6

    CAS:
    <p>AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].</p>
    Formula:C24H36N2O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:480.68
  • L-822179

    CAS:
    <p>L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.</p>
    Formula:C17H14N8O2
    Purity:98.5% - 99.61%
    Color and Shape:Solid
    Molecular weight:362.35
  • mGAT3/4-IN-2

    CAS:
    <p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>
    Formula:C26H32ClN3OS2
    Color and Shape:Solid
    Molecular weight:502.13
  • LY 53857

    CAS:
    <p>LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.</p>
    Formula:C27H36N2O7
    Color and Shape:Solid
    Molecular weight:500.592
  • LY2033298

    CAS:
    <p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>
    Formula:C13H14ClN3O2S
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:311.79
  • KBR 2822

    CAS:
    <p>KBR 2822 is an inhibitor of esterase.</p>
    Formula:C9H15ClF3O3PS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:326.7
  • RAGE/SERT-IN-1

    CAS:
    <p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>
    Formula:C38H41ClN4OS
    Color and Shape:Solid
    Molecular weight:637.28
  • LY-426965

    CAS:
    <p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>
    Formula:C28H38N2O2
    Color and Shape:Solid
    Molecular weight:434.61
  • BMS-983970

    CAS:
    <p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>
    Formula:C26H26F4N4O3
    Color and Shape:Solid
    Molecular weight:518.5
  • Lanabecestat

    CAS:
    <p>Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.</p>
    Formula:C26H28N4O
    Purity:98.55%
    Color and Shape:Solid
    Molecular weight:412.53
  • Brilaroxazine

    CAS:
    <p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>
    Formula:C22H25Cl2N3O3
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:450.36
  • ADX71441

    CAS:
    <p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events &amp; volume, and may aid in alcoholism and bladder pain.</p>
    Formula:C19H15ClF2N4O4
    Color and Shape:Solid
    Molecular weight:436.8
  • LY320954

    CAS:
    <p>LY320954 is an antagonist of 5-HT2A receptor.</p>
    Formula:C21H26N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:382.46
  • QM-FN-SO3

    CAS:
    <p>QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].</p>
    Formula:C29H25N4NaO3S2
    Color and Shape:Solid
    Molecular weight:564.65
  • AMPA receptor modulator-5

    CAS:
    <p>AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].</p>
    Formula:C20H12F4N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:412.34
  • P11149

    CAS:
    <p>P11149: oral AChE inhibitor, crosses BBB, IC50 1.3 μM, based on Galanthamine, aims Alzheimer's research.</p>
    Formula:C27H34ClNO4
    Color and Shape:Solid
    Molecular weight:472.02
  • PZ-II-029

    CAS:
    <p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>
    Formula:C18H15N3O3
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:321.33
  • Cyclophostin

    CAS:
    <p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>
    Formula:C8H11O6P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:234.14
  • 5-HT2C agonist-3 free base

    CAS:
    <p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>
    Formula:C19H22FNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.38
  • 5-HT3-In-1

    CAS:
    <p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>
    Formula:C16H21ClN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:352.82
  • 5-HT2A receptor agonist-3

    CAS:
    <p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>
    Formula:C21H26BrNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:420.34
  • Calmidazolium chloride

    CAS:
    <p>Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.</p>
    Formula:C31H23Cl7N2O
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:687.7
  • AAK1-IN-4

    CAS:
    <p>AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.</p>
    Formula:C20H28N4O3
    Color and Shape:Solid
    Molecular weight:372.46
  • MAO-IN-3

    CAS:
    <p>MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,</p>
    Formula:C42H54N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:678.9
  • FPTQ

    CAS:
    <p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>
    Formula:C17H12FN5
    Purity:99.68% - 99.88%
    Color and Shape:Solid
    Molecular weight:305.31
  • (+)-Bicuculline methiodide

    CAS:
    <p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>
    Formula:C21H20INO6
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:509.29
  • MAO-B-IN-13

    CAS:
    <p>MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).</p>
    Formula:C18H19NO3
    Color and Shape:Solid
    Molecular weight:297.35
  • GR 127935 hydrochloride

    CAS:
    <p>5-HT1B/1D receptor antagonist</p>
    Formula:C29H32ClN5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.05
  • CP-122288

    CAS:
    <p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>
    Formula:C16H23N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.44