Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,024 products)
- ACK(1 products)
- AChR(623 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,030 products)
- BACE(36 products)
- Beta Amyloid(223 products)
- CaMK(72 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(443 products)
- GABA Receptor(365 products)
- Gamma-secretase(62 products)
- GluR(263 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(42 products)
- Melatonin Receptor(26 products)
- NMDAR(11 products)
- OX Receptor(41 products)
- Opioid Receptor(326 products)
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Found 5559 products of "Neuroscience"
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KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Dapoxetine
CAS:Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.Formula:C21H23NOPurity:99.73%Color and Shape:White To Off-White Crystalline PowderMolecular weight:305.42PSEN1-IN-1
PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50Formula:C20H19ClF3NO3SColor and Shape:SolidMolecular weight:445.88GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.Formula:C20H20FN3OColor and Shape:SolidMolecular weight:337.391NMDAR antagonist 2
NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.Formula:C17H20ClNOColor and Shape:SolidMolecular weight:289.8BU 226 hydrochloride
CAS:BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM.Formula:C12H12ClN3Purity:99.67%Color and Shape:SolidMolecular weight:233.7Timegadine hydrochloride
CAS:Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.Formula:C20H24ClN5SColor and Shape:SolidMolecular weight:401.96GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Formula:C18H22O2Color and Shape:SolidMolecular weight:270.37Notch 1
CAS:Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.Formula:C62H97N15O22S3Color and Shape:SolidMolecular weight:1500.72Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formula:C16H20ClNOPurity:98.97% - 99.9%Color and Shape:SoildMolecular weight:277.79Ref: TM-T67956L
1mg97.00€5mg217.00€10mg325.00€25mg557.00€50mg797.00€100mg1,103.00€1mL*10mM (DMSO)208.00€3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
CAS:3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) can be used in related research in the field of life sciences.Formula:C10H10ClNaO3Color and Shape:SolidMolecular weight:236.63M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Color and Shape:Odour SolidPirimiphos-ethyl
CAS:Pirimiphos-ethyl is used as an organophosphorus pesticide.Formula:C13H24N3O3PSPurity:98%Color and Shape:SolidMolecular weight:333.39Methyl piperate
CAS:Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibitionFormula:C13H12O4Purity:98%Color and Shape:SolidMolecular weight:232.23AAK1-IN-9
AAK1-IN-9 (Compound 3) is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 value of 10.92 nM, and it is applicable in the study of neurodegenerative diseases.Color and Shape:Odour Solidγ-DGG TFA
CAS:Gamma-DGG TFA is an antagonist of excitatory amino acids that can inhibit depolarization induced by NMDA, Kainate, and Quisqualate. In addition, it counteracts excitatory postsynaptic potentials (e.p.s.p.) in rat hippocampal slices.Formula:C9H13F3N2O7Color and Shape:SolidMolecular weight:318.2(D-Asp1)-Amyloid β-Protein (1-42)
CAS:(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid depositsFormula:C203H311N55O60SColor and Shape:SolidMolecular weight:4514.04Graphislactone A
CAS:Graphislactone A, an antioxidant from Cephalosporium and M. olivacea, scavenges radicals and reduces LDL peroxidation, inhibits AChE (IC50: 27μM).Formula:C16H14O6Color and Shape:SolidMolecular weight:302.28G923-0271
CAS:<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Formula:C28H23FN4OColor and Shape:SolidMolecular weight:450.51hAChE-IN-4
Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study ofFormula:C30H23Cl3N2O3Color and Shape:SolidMolecular weight:565.87
