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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • 2002-G12
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    2002-G12

    CAS:
    <p>2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. It is applicable in Alzheimer's research.</p>
    Formula:C20H16N6
    Color and Shape:Solid
    Molecular weight:340.381

    Ref: TM-T204830

  • AAZ-A 154 hydrobromide
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    AAZ-A 154 hydrobromide

    CAS:
    <p>AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.</p>
    Formula:C14H21BrN2O
    Color and Shape:Solid
    Molecular weight:313.23

    Ref: TM-T200446

  • AAZ-A 154 benzoate
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    AAZ-A 154 benzoate

    CAS:
    <p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>
    Formula:C21H26N2O3
    Color and Shape:Solid
    Molecular weight:354.44

    Ref: TM-T200491

  • Amyloid-β-IN-3
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    Amyloid-β-IN-3

    CAS:
    <p>Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.</p>
    Formula:C22H21F2N3O2
    Color and Shape:Solid
    Molecular weight:397.42

    Ref: TM-T207233

  • VA012
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    VA012

    CAS:
    <p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>
    Formula:C21H19N3
    Color and Shape:Solid
    Molecular weight:313.40

    Ref: TM-T200241

  • DL-AP5 lithium
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    DL-AP5 lithium

    CAS:
    <p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>
    Formula:C5H11LiNO5P
    Color and Shape:Solid
    Molecular weight:203.06

    Ref: TM-T201724

  • CL-13
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    CL-13

    <p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>
    Formula:C29H32N4OS
    Color and Shape:Solid
    Molecular weight:484.66

    Ref: TM-T201512

  • AChE/BChE-IN-24
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    AChE/BChE-IN-24

    CAS:
    <p>AChE/BChE-IN-24 (compound 5k) functions as a neuroprotective agent by inhibiting acetylcholinesterase. It targets both AChE and BChE, demonstrating IC50 values of 16.38 μM and 10.44 μM, respectively.</p>
    Formula:C20H21N3
    Color and Shape:Solid
    Molecular weight:303.4

    Ref: TM-T201846

  • Ro4368554
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    Ro4368554

    CAS:
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Formula:C19H21N3O2S
    Color and Shape:Solid
    Molecular weight:355.454

    Ref: TM-T204915

  • YM 202074
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    YM 202074

    CAS:
    <p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>
    Formula:C56H72N8O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1177.34

    Ref: TM-T23544

  • BACE1-IN-4
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    BACE1-IN-4

    CAS:
    <p>BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.</p>
    Formula:C21H23F2N5O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.57

    Ref: TM-T10452

  • Pareptide monohydrochloride
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    Pareptide monohydrochloride

    CAS:
    <p>Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).</p>
    Formula:C14H27ClN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:334.84

    Ref: TM-T13707

  • Poskine
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    Poskine

    CAS:
    <p>Poskine is an anticholinergic and central nervous system depressant. It is utilized in research related to Parkinson's disease and motion sickness.</p>
    Formula:C20H25NO5
    Color and Shape:Solid
    Molecular weight:359.42

    Ref: TM-T201100

  • CymitQuimica logo
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    nAChR antagonist 1

    CAS:
    <p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>
    Formula:C19H22N4O2
    Color and Shape:Solid
    Molecular weight:338.4

    Ref: TM-T61064

  • Terguride
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    Terguride

    CAS:
    <p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>
    Formula:C20H28N4O
    Color and Shape:Solid
    Molecular weight:340.46

    Ref: TM-T71847

  • CymitQuimica logo
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    AAK1-IN-2 TFA

    <p>AAK1-IN-2 TFA (compound (S)-31) is a selective and potent AAK1 inhibitor (IC50: 5.8 nM) that can cross the blood-brain barrier.</p>
    Formula:C24H22F6N4O4
    Color and Shape:Solid
    Molecular weight:544.45

    Ref: TM-T63833

  • Geissoschizoline
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    Geissoschizoline

    CAS:
    <p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>
    Formula:C19H26N2O
    Color and Shape:Solid
    Molecular weight:298.42

    Ref: TM-T72733

  • CymitQuimica logo
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    LRRK2-IN-6

    <p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>
    Formula:C23H24F2N4O2S
    Color and Shape:Solid
    Molecular weight:458.52

    Ref: TM-T62871

  • BGT1-IN-1
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    BGT1-IN-1

    CAS:
    <p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>
    Formula:C6H9NO2
    Color and Shape:Solid
    Molecular weight:127.14

    Ref: TM-T200935

  • Nedemelteon
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    Nedemelteon

    CAS:
    <p>Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).</p>
    Formula:C15H18N2O2
    Color and Shape:Solid
    Molecular weight:258.32

    Ref: TM-T201036