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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • HW161023
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    HW161023

    CAS:
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Formula:C20H24F2N4O
    Color and Shape:Solid
    Molecular weight:374.428

    Ref: TM-T206896

  • YM 202074
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    YM 202074

    CAS:
    <p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>
    Formula:C56H72N8O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1177.34

    Ref: TM-T23544

  • R-96544 hydrochloride
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    R-96544 hydrochloride

    CAS:
    <p>5-HT2 receptor antagonist</p>
    Formula:C22H29NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:355.47

    Ref: TM-T23219

  • SB 243213 dihydrochloride
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    SB 243213 dihydrochloride

    CAS:
    <p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>
    Formula:C22H21Cl2F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:501.33

    Ref: TM-T12859L

  • PTCA
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    PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Formula:C10H5Cl2NO2S
    Color and Shape:Solid
    Molecular weight:274.123

    Ref: TM-T204835

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    BChE-IN-3

    <p>BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.</p>
    Formula:C26H41N3O2
    Color and Shape:Solid
    Molecular weight:427.62

    Ref: TM-T62336

  • PXS-5153A monohydrochloride
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    PXS-5153A monohydrochloride

    CAS:
    <p>PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 &lt;40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.</p>
    Formula:C20H25Cl2FN4O2S
    Purity:98%
    Color and Shape:Odour Solid
    Molecular weight:475.41

    Ref: TM-T12585L

  • HDAC6-IN-9
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    HDAC6-IN-9

    CAS:
    <p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>
    Formula:C19H16N2O3
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:320.34

    Ref: TM-T60856

  • COX-2-IN-47
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    COX-2-IN-47

    CAS:
    <p>COX-2-IN-47 (compound 6c) is a selective inhibitor of COX-2, exhibiting an IC50 of 0.03 μM. This compound also displays antiedema activity.</p>
    Formula:C18H18N2O4
    Color and Shape:Solid
    Molecular weight:326.35

    Ref: TM-T200034

  • LOXL2-IN-1 tosylate
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    LOXL2-IN-1 tosylate

    <p>LOX-IN-5 tosylate (compound 22) is a selective oral inhibitor of lysyl oxidase-like 2 (LOXL2) with an IC50 of less than 300 nM, and it exhibits anti-fibrotic properties.</p>
    Formula:C28H33FN4O5S2
    Color and Shape:Solid
    Molecular weight:588.714

    Ref: TM-T205044

  • MAO-A inhibitor 3
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    MAO-A inhibitor 3

    CAS:
    <p>MAO-A inhibitor3 (Compound 360) is an MAO-A inhibitor with an IC50 greater than 100 μM. It is utilized in the investigation of neurological disorders.</p>
    Formula:C11H8O5
    Color and Shape:Solid
    Molecular weight:220.178

    Ref: TM-T205117

  • hAChE-IN-10
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    hAChE-IN-10

    CAS:
    <p>hAChE-IN-10 (Compound ET11) is an inhibitor of human acetylcholinesterase (AChE) with an IC50 of 6.34 nM. This compound is capable of scavenging free radicals and exhibits antioxidant activity. Additionally, hAChE-IN-10 demonstrates metal-chelating properties, inhibiting Cu2+-induced Aβ1-42 aggregation, reducing amyloid plaque formation, and offering neuroprotective effects. It also ameliorates cognitive impairment in mice induced by Scopolamine.</p>
    Formula:C25H24ClFN6O2
    Color and Shape:Solid
    Molecular weight:494.948

    Ref: TM-T204876

  • Ro4368554
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    Ro4368554

    CAS:
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Formula:C19H21N3O2S
    Color and Shape:Solid
    Molecular weight:355.454

    Ref: TM-T204915

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    AChE/BChE-IN-19

    CAS:
    <p>AChE/BChE-IN-19 (compound 12) is a nicotinic hydrazine derivative that acts as an inhibitor of AChE (IC50=21.45 nM) and BChE (IC50=18.42 nM), and it is applicable in Alzheimer's disease research.</p>
    Formula:C26H22N4O3
    Molecular weight:438.48

    Ref: TM-T209831

  • GABA-IN-4
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    GABA-IN-4

    CAS:
    <p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>
    Formula:C17H13ClN2O2
    Color and Shape:Solid
    Molecular weight:312.75

    Ref: TM-T205501

  • BF-168
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    BF-168

    CAS:
    <p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>
    Formula:C18H17FN2O2
    Color and Shape:Solid
    Molecular weight:312.34

    Ref: TM-T10529

  • 5-IAI hydrochloride
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    5-IAI hydrochloride

    CAS:
    <p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>
    Formula:C9H11ClIN
    Color and Shape:Solid
    Molecular weight:295.548

    Ref: TM-T204949

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    CaMKK2-IN-1

    CAS:
    <p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>
    Formula:C22H22N2O3
    Molecular weight:362.42

    Ref: TM-T208827

  • Aβ42-IN-1
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    Aβ42-IN-1

    CAS:
    <p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Formula:C29H27ClN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:499

    Ref: TM-T10211

  • VA012
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    VA012

    CAS:
    <p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>
    Formula:C21H19N3
    Color and Shape:Solid
    Molecular weight:313.40

    Ref: TM-T200241