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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • LRRK2-IN-16

    CAS:
    <p>LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.</p>
    Formula:C18H19N5OS
    Color and Shape:Solid
    Molecular weight:353.441
  • Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Formula:C14H16N2O5
    Color and Shape:Solid
    Molecular weight:292.287
  • SB 243213 hydrochloride

    CAS:
    <p>SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).It</p>
    Formula:C22H20ClF3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:464.87
  • hAChE/Aβ1-42-IN-1

    CAS:
    <p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>
    Formula:C20H24N6O
    Color and Shape:Solid
    Molecular weight:364.44
  • Glutaminyl Cyclase Inhibitor 3

    CAS:
    <p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>
    Formula:C24H32N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.61
  • (E)-CHBO4

    CAS:
    <p>(E)-CHBO4 is an MAO-B inhibitor with an IC50 value of 0.023 μM, making it a potential candidate for research into Parkinson's disease treatment.</p>
    Formula:C15H10BrFO
    Color and Shape:Solid
    Molecular weight:305.142
  • Notch inhibitor 1

    CAS:
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Formula:C26H25F7N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:574.49
  • S-8510 phosphate

    CAS:
    <p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>
    Formula:C12H13N4O6P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:340.23
  • MADAM

    CAS:
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Formula:C16H20N2S
    Color and Shape:Solid
    Molecular weight:272.408
  • BChE-IN-38

    CAS:
    <p>BChE-IN-38 (compound 13) is a potent BChE inhibitor, with Ki values of 62.05, 28.78, 14.09, and 1.15 nM for hCAI, hCAII, AChE, and BChE, respectively. BChE-IN-38 also demonstrates cytotoxic activity.</p>
    Formula:C27H20N4
    Color and Shape:Solid
    Molecular weight:400.474
  • K027


    <p>K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.</p>
    Formula:C15H18Br2N4O2
    Color and Shape:Solid
    Molecular weight:446.14
  • LRRK2-IN-2

    CAS:
    <p>LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.</p>
    Formula:C23H23Cl2F3N6O2
    Color and Shape:Solid
    Molecular weight:543.37
  • 2,6-Dimethoxybenzylamine hydrochloride

    CAS:
    <p>2,6-Dimethoxybenzylamine hydrochloride (Compound 5) exhibits reversible inhibitory activity against copper amine oxidase (CAO) and inhibits benzylamine oxidase (BAO) and monoamine oxidase B (MAO B) with IC50 values of 120 μM and 190 μM, respectively.</p>
    Formula:C9H14ClNO2
    Color and Shape:Solid
    Molecular weight:203.666
  • P2X4 antagonist-1

    CAS:
    <p>P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.</p>
    Formula:C20H15Cl3N2O4S
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:485.77
  • FP0429

    CAS:
    <p>FP0429 is an agonist of mGlu4.</p>
    Formula:C10H12N2O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:272.21
  • (+)-Cevimeline hydrochloride hemihydrate


    <p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>
    Formula:C10H19ClNO1·5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:244.78
  • PF-06648671

    CAS:
    <p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>
    Formula:C25H23ClF4N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.92
  • BRD0418

    CAS:
    <p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>
    Formula:C29H32N2O5
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:488.57
  • VU6005806

    CAS:
    <p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>
    Formula:C17H16F3N7O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.41
  • RO-1-5237

    CAS:
    <p>RO-1-5237, a cholinergic compound and a metabolic product of Pyridostigmine Bromide, is utilized in research for myasthenia gravis.</p>
    Formula:C6H8BrNO
    Color and Shape:Solid
    Molecular weight:190.04