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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5398 products of "Neuroscience"

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  • SB 224289
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    SB 224289

    CAS:
    <p>SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.</p>
    Formula:C32H32N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.62

    Ref: TM-T19690

  • MAO-B-IN-42
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    MAO-B-IN-42

    CAS:
    <p>MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.</p>
    Formula:C19H12FNO2
    Color and Shape:Solid
    Molecular weight:305.302

    Ref: TM-T206712

  • AChE-IN-63
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    AChE-IN-63

    CAS:
    <p>AChE-IN-63 (Compound 5AD) serves as a selective inhibitor of hAChE, exhibiting an IC 50 value of 0.103 μM. Moreover, it inhibits hBChE and hBACE-1 with IC 50 values of 10 μM and 1.342 μM, respectively. AChE-IN-63 is effective in inhibiting Aβ aggregation and preventing the formation and deposition of Aβ1-42. It can effectively penetrate the blood-brain barrier and is orally bioavailable. This compound is primarily utilized in research related to Alzheimer's disease [1].</p>
    Formula:C18H19N5O
    Color and Shape:Solid
    Molecular weight:321.38

    Ref: TM-T85555

  • Amyloid-β-IN-2
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    Amyloid-β-IN-2

    CAS:
    <p>Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.</p>
    Formula:C22H21F2N3O2
    Color and Shape:Solid
    Molecular weight:397.42

    Ref: TM-T207418

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    β-Secretase Inhibitor III

    <p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>
    Formula:C20H20F2N4O3S
    Color and Shape:Solid
    Molecular weight:434.46

    Ref: TM-T62455

  • Tebideutorexant
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    Tebideutorexant

    CAS:
    <p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>
    Formula:C23H16D2F4N4O2
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:460.42

    Ref: TM-T70332

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    ChE/Aβ1-42-IN-1

    <p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>
    Formula:C19H24N2O3
    Color and Shape:Solid
    Molecular weight:328.41

    Ref: TM-T60940

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    Monoamine Oxidase B inhibitor 2

    <p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>
    Formula:C19H19FO3
    Color and Shape:Solid
    Molecular weight:314.35

    Ref: TM-T60806

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    cSPM

    <p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>
    Formula:C27H57N7
    Color and Shape:Solid
    Molecular weight:479.79

    Ref: TM-T63163

  • CVN636
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    CVN636

    CAS:
    <p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>
    Formula:C19H20FNO4S
    Color and Shape:Solid
    Molecular weight:377.43

    Ref: TM-T78090

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    LRRK2-IN-6

    <p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>
    Formula:C23H24F2N4O2S
    Color and Shape:Solid
    Molecular weight:458.52

    Ref: TM-T62871

  • BACE1-IN-2
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    BACE1-IN-2

    CAS:
    <p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>
    Formula:C19H15F4N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.35

    Ref: TM-T10451

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    5-HT6R/MAO-B modulator 1

    <p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>
    Formula:C33H38N4O3S
    Color and Shape:Solid
    Molecular weight:570.74

    Ref: TM-T64036

  • Buntanetap L-Tartrate
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    Buntanetap L-Tartrate

    CAS:
    <p>Buntanetap (L-Tartrate) functions as an oral small molecule inhibitor targeting multiple neurotoxic proteins. It decreases the production of amyloid precursor protein (APP) by inhibiting the translation of its mRNA [1].</p>
    Formula:C24H29N3O8
    Color and Shape:Solid
    Molecular weight:487.50

    Ref: TM-T85929

  • VU6005806
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    VU6005806

    CAS:
    <p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>
    Formula:C17H16F3N7O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.41

    Ref: TM-T13322

  • LRRK2-IN-3
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    LRRK2-IN-3

    CAS:
    <p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>
    Formula:C25H29ClF2N6O2
    Color and Shape:Solid
    Molecular weight:518.99

    Ref: TM-T63620

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    AChE-IN-24

    <p>AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.</p>
    Formula:C22H30N2O4S2
    Color and Shape:Solid
    Molecular weight:450.61

    Ref: TM-T62728

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    AZD 2066 hydrate

    <p>AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].</p>
    Formula:C19H18ClN5O3
    Color and Shape:Solid
    Molecular weight:386.33

    Ref: TM-T61708

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    AChE-IN-8

    <p>AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.</p>
    Formula:C20H22N4O2S
    Color and Shape:Solid
    Molecular weight:382.48

    Ref: TM-T61648

  • Geissoschizoline
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    Geissoschizoline

    CAS:
    <p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>
    Formula:C19H26N2O
    Color and Shape:Solid
    Molecular weight:298.42

    Ref: TM-T72733