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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5398 products of "Neuroscience"

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  • SB 243213 dihydrochloride
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    SB 243213 dihydrochloride

    CAS:
    <p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>
    Formula:C22H21Cl2F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:501.33

    Ref: TM-T12859L

  • DL-Thyroxine
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    DL-Thyroxine

    CAS:
    <p>DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor.</p>
    Formula:C15H11I4NO4
    Color and Shape:Solid
    Molecular weight:776.87

    Ref: TM-T204436

  • MAO-B-IN-42
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    MAO-B-IN-42

    CAS:
    <p>MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.</p>
    Formula:C19H12FNO2
    Color and Shape:Solid
    Molecular weight:305.302

    Ref: TM-T206712

  • AChE/BChE/MAO-B-IN-5
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    AChE/BChE/MAO-B-IN-5

    CAS:
    <p>AChE/BChE/MAO-B-IN-5 is a multi-target inhibitor capable of crossing the blood-brain barrier, targeting cholinesterases (AChE and BChE) and monoamine oxidase MAO-B. It exhibits IC50 values of 0.24 µM for AChE, 6.29 µM for BChE, and 0.11 µM for MAO-B. AChE/BChE/MAO-B-IN-5 holds potential for research in neurodegenerative diseases such as Alzheimer's disease.</p>
    Formula:C22H14F3NO2
    Color and Shape:Solid
    Molecular weight:381.347

    Ref: TM-T206229

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    LRRK2-IN-6

    <p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>
    Formula:C23H24F2N4O2S
    Color and Shape:Solid
    Molecular weight:458.52

    Ref: TM-T62871

  • VU6007496
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    VU6007496

    CAS:
    <p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>
    Formula:C25H27N5O2
    Color and Shape:Solid
    Molecular weight:429.51

    Ref: TM-T200762

  • AAZ-A 154
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    AAZ-A 154

    CAS:
    <p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>
    Formula:C14H20N2O
    Color and Shape:Solid
    Molecular weight:232.32

    Ref: TM-T200737

  • THRX-194556
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    THRX-194556

    CAS:
    <p>THRX-194556 is an agonist of the 5-HT4 receptor. It is applicable in the study of gastrointestinal functional disorders and Alzheimer's disease.</p>
    Formula:C28H41N5O5S
    Color and Shape:Solid
    Molecular weight:559.721

    Ref: TM-T205695

  • Notch inhibitor 1
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    Notch inhibitor 1

    CAS:
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Formula:C26H25F7N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:574.49

    Ref: TM-T16341

  • F 14679
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    F 14679

    CAS:
    <p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>
    Formula:C21H25ClF2N4O
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:422.9

    Ref: TM-T62269

  • YM-31636 free base
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    YM-31636 free base

    CAS:
    <p>YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.</p>
    Formula:C14H11N3S
    Color and Shape:Solid
    Molecular weight:253.32

    Ref: TM-T201587

  • ASP-2205
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    ASP-2205

    CAS:
    <p>ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.</p>
    Formula:C19H28N2O
    Color and Shape:Solid
    Molecular weight:300.44

    Ref: TM-T201450

  • Elzasonan hydrochloride
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    Elzasonan hydrochloride

    CAS:
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Formula:C22H24Cl3N3OS
    Color and Shape:Solid
    Molecular weight:484.87

    Ref: TM-T201763

  • hMAO-B-IN-10
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    hMAO-B-IN-10

    <p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>
    Formula:C16H12N4O4
    Color and Shape:Solid
    Molecular weight:324.29

    Ref: TM-T201531

  • SGE-516
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    SGE-516

    CAS:
    <p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>
    Formula:C23H35N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:385.54

    Ref: TM-T28766

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    AZD 2066 hydrate

    <p>AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].</p>
    Formula:C19H18ClN5O3
    Color and Shape:Solid
    Molecular weight:386.33

    Ref: TM-T61708

  • AGH-107
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    AGH-107

    CAS:
    <p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>
    Formula:C13H12IN3
    Color and Shape:Solid
    Molecular weight:337.16

    Ref: TM-T201735

  • Flucopride
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    Flucopride

    CAS:
    <p>Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.</p>
    Formula:C22H33FN2O2
    Color and Shape:Solid
    Molecular weight:376.51

    Ref: TM-T201815

  • R-137696
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    R-137696

    CAS:
    <p>R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.</p>
    Formula:C17H23N3O2
    Color and Shape:Solid
    Molecular weight:301.38

    Ref: TM-T201501

  • Neral
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    Neral

    CAS:
    <p>Neral, a monoterpenoid compound, exhibits anti-inflammatory and anticancer activities. It inhibits TNF-α and IL-6, along with inflammatory mediators such as pro-IL-1β, iNOS, COX-2, and NLRP-3.</p>
    Formula:C10H16O
    Color and Shape:Solid
    Molecular weight:152.23

    Ref: TM-T201808