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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • DA-8031

    CAS:
    <p>DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).</p>
    Formula:C21H24N2O2
    Color and Shape:Solid
    Molecular weight:336.43
  • BChE-IN-3


    <p>BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.</p>
    Formula:C26H41N3O2
    Color and Shape:Solid
    Molecular weight:427.62
  • PXS-4787 hydrochloride

    CAS:
    <p>PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.</p>
    Formula:C10H13ClFNO2S
    Color and Shape:Solid
    Molecular weight:265.73
  • HW161023

    CAS:
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Formula:C20H24F2N4O
    Color and Shape:Solid
    Molecular weight:374.428
  • Elzasonan hydrochloride

    CAS:
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Formula:C22H24Cl3N3OS
    Color and Shape:Solid
    Molecular weight:484.87
  • Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Formula:C24H29F2N3O2
    Color and Shape:Solid
    Molecular weight:429.50
  • Geissoschizoline

    CAS:
    <p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>
    Formula:C19H26N2O
    Color and Shape:Solid
    Molecular weight:298.42
  • CEase-IN-1


    <p>CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.</p>
    Formula:C13H15F3N2O2
    Color and Shape:Solid
    Molecular weight:288.27
  • AChE-IN-84

    CAS:
    <p>AChE-IN-84 (compound 21) is an inhibitor of AChE.</p>
    Formula:C6H15Br2N
    Color and Shape:Solid
    Molecular weight:260.998
  • 5-HT7R antagonist 3

    CAS:
    <p>Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.</p>
    Formula:C30H33FN4O3
    Color and Shape:Solid
    Molecular weight:516.61
  • Zanapezil fumarate

    CAS:
    <p>Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.</p>
    Formula:C29H36N2O5
    Color and Shape:Solid
    Molecular weight:492.61
  • Dual AChE-MAO B-IN-1


    <p>Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.</p>
    Formula:C23H25F2NO4
    Color and Shape:Solid
    Molecular weight:417.45
  • eeAChE-IN-1


    <p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>
    Formula:C27H30N6O5S
    Color and Shape:Solid
    Molecular weight:550.63
  • AChE/BChE-IN-19

    CAS:
    <p>AChE/BChE-IN-19 (compound 12) is a nicotinic hydrazine derivative that acts as an inhibitor of AChE (IC50=21.45 nM) and BChE (IC50=18.42 nM), and it is applicable in Alzheimer's disease research.</p>
    Formula:C26H22N4O3
    Molecular weight:438.48
  • Nafimidone hydrochloride

    CAS:
    <p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>
    Formula:C15H13ClN2O
    Color and Shape:Solid
    Molecular weight:272.73
  • MAO-B-IN-28

    CAS:
    <p>MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 value of 1.9±0.5 nM, potentially serving as a candidate molecule for neurodegenerative disease research.</p>
    Formula:C19H10F3NO4S
    Molecular weight:405.35
  • AZD 2066 hydrate


    <p>AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].</p>
    Formula:C19H18ClN5O3
    Color and Shape:Solid
    Molecular weight:386.33
  • AChE-IN-24


    <p>AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.</p>
    Formula:C22H30N2O4S2
    Color and Shape:Solid
    Molecular weight:450.61
  • CVN636

    CAS:
    <p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>
    Formula:C19H20FNO4S
    Color and Shape:Solid
    Molecular weight:377.43
  • Aβ-IN-2


    <p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>
    Formula:C37H51NO
    Color and Shape:Solid
    Molecular weight:525.81