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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5398 products of "Neuroscience"

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  • Litoxetine HCl


    <p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>
    Formula:C16H20ClNO
    Purity:99.56% - 99.75%
    Color and Shape:Soild
    Molecular weight:277.79
  • Desfesoterodine

    CAS:
    <p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>
    Formula:C22H31NO2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:341.49
  • Tropicamide

    CAS:
    <p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>
    Formula:C17H20N2O2
    Purity:99.78% - 99.94%
    Color and Shape:White Powder
    Molecular weight:284.35
  • AZD4694 Precursor

    CAS:
    <p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>
    Formula:C22H25N3O7
    Color and Shape:Solid
    Molecular weight:443.45
  • 5-HT1AR/5-HT6R ligand-1


    <p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>
    Formula:C25H29ClN4O2S
    Color and Shape:Solid
    Molecular weight:485.04
  • Mesoridazine Besylate

    CAS:
    <p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>
    Formula:C27H32N2O4S3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:544.75
  • CHF-5022

    CAS:
    <p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>
    Formula:C17H12F4O2
    Color and Shape:Solid
    Molecular weight:324.27
  • Cianopramine hydrochloride

    CAS:
    <p>Cianopramine hydrochloride is a bio-active chemical.</p>
    Formula:C20H24ClN3
    Color and Shape:Solid
    Molecular weight:341.88
  • Br-PBTC

    CAS:
    <p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>
    Formula:C14H15BrN2OS
    Color and Shape:Solid
    Molecular weight:339.25
  • PD25


    <p>PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.</p>
    Formula:C25H24N2O4
    Color and Shape:Solid
    Molecular weight:416.47
  • DDC 2′,3′-O-disulfate


    <p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>
    Formula:C17H16O11S2
    Color and Shape:Solid
    Molecular weight:460.43
  • β-Amyloid Protein Precursor 770 (135-155)

    CAS:
    <p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>
    Formula:C116H172N35O31S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2617.96
  • (Gln22)-Amyloid β-Protein (1-42)

    CAS:
    <p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>
    Formula:C203H312N56O59S
    Color and Shape:Solid
    Molecular weight:4513.05
  • AChE-IN-37


    <p>AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.</p>
    Formula:C21H12ClNO7S
    Color and Shape:Solid
    Molecular weight:457.84
  • Triazolomethylindole-3-acetic acid

    CAS:
    <p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>
    Formula:C13H12N4O2
    Color and Shape:Solid
    Molecular weight:256.26
  • Aβ-IN-8


    <p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>
    Formula:C22H16F3N3O3S
    Color and Shape:Solid
    Molecular weight:459.44
  • Ro60-0175

    CAS:
    <p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>
    Formula:C11H12ClFN2
    Purity:97.09%
    Color and Shape:Solid
    Molecular weight:226.68
  • TAT-CN21


    <p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>
    Formula:C169H303N69O43
    Color and Shape:Solid
    Molecular weight:3989.65
  • AChE/BuChE/MAO-B-IN-2


    <p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>
    Formula:C19H18FNO3
    Color and Shape:Solid
    Molecular weight:327.35
  • Anticonvulsant agent 9


    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Formula:C22H24N4O2
    Color and Shape:Solid
    Molecular weight:376.45