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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5398 products of "Neuroscience"

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  • CymitQuimica logo
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    PD24

    <p>PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for human</p>
    Formula:C24H22N2O6
    Color and Shape:Solid
    Molecular weight:434.44

    Ref: TM-T79502

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    XL01126

    <p>XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.</p>
    Formula:C50H64ClFN10O6S2
    Color and Shape:Solid
    Molecular weight:1019.69

    Ref: TM-T74638

  • FRM-024
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    FRM-024

    CAS:
    <p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>
    Formula:C22H22ClN5O2
    Color and Shape:Solid
    Molecular weight:423.9

    Ref: TM-T39492

  • p-HTAA
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    p-HTAA

    CAS:
    <p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>
    Formula:C24H16O4S5
    Color and Shape:Solid
    Molecular weight:528.71

    Ref: TM-T74711

  • Sintamil
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    Sintamil

    CAS:
    <p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>
    Formula:C18H20ClN3O4
    Color and Shape:Solid
    Molecular weight:377.82

    Ref: TM-T71697

  • MGS0028
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    MGS0028

    CAS:
    <p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>
    Formula:C8H8FNO5
    Color and Shape:Solid
    Molecular weight:217.15

    Ref: TM-T28033

  • Atagabalin
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    Atagabalin

    CAS:
    <p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>
    Formula:C10H19NO2
    Color and Shape:Solid
    Molecular weight:185.26

    Ref: TM-T30188

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    RA306

    <p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206515

  • OXA(17-33)
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    OXA(17-33)

    CAS:
    <p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>
    Formula:C79H125N23O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1749

    Ref: TM-TP1973

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    COX-1/2-IN-4

    <p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>
    Formula:C22H24N2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.5

    Ref: TM-T79592

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    NMDA receptor antagonist 8

    <p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>
    Formula:C22H27N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.47

    Ref: TM-T79375

  • α5-GABAA receptor modulator 1
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    α5-GABAA receptor modulator 1

    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Formula:C21H20FN3O4
    Color and Shape:Solid
    Molecular weight:397.4

    Ref: TM-T205217

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    COX-2-IN-33

    <p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>
    Formula:C20H13ClF3N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:479.8

    Ref: TM-T78754

  • 2'-O-Succinyl-cAMP
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    2'-O-Succinyl-cAMP

    CAS:
    <p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>
    Formula:C14H16N5O9P
    Color and Shape:Solid
    Molecular weight:429.282

    Ref: TM-T35421

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    IHC3

    <p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>
    Formula:C17H12FN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:293.3

    Ref: TM-T78821

  • MAOA-IN-1
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    MAOA-IN-1

    <p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>
    Formula:C13H16Cl2N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:303.18

    Ref: TM-T78793

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    BChE-IN-21

    <p>BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in</p>
    Color and Shape:Odour Solid

    Ref: TM-T82915

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    GABA receptor Antagonist 1

    <p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>
    Purity:98%
    Color and Shape:Odour Solid

    Ref: TM-T82357

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    MAO-B-IN-3

    <p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>
    Formula:C24H25N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.47

    Ref: TM-T78648

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    5-HT1AR/5-HT6R ligand-1

    <p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>
    Formula:C25H29ClN4O2S
    Color and Shape:Solid
    Molecular weight:485.04

    Ref: TM-T205634