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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5389 products of "Neuroscience"

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  • BChE-IN-10
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    BChE-IN-10

    CAS:
    <p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>
    Formula:C23H20O5
    Color and Shape:Solid
    Molecular weight:376.4

    Ref: TM-T75511

  • β-Amyloid (1-9)
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    β-Amyloid (1-9)

    CAS:
    <p>This is an N-terminal fragment of beta amyloid.</p>
    Formula:C42H60N14O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1033.01

    Ref: TM-TP1645

  • Riluzole-13C,15N2
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    Riluzole-13C,15N2

    CAS:
    <p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>
    Formula:CC7H5F3OS15N2
    Color and Shape:Solid
    Molecular weight:237.18

    Ref: TM-T37608

  • Methyllycaconitine citrate
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    Methyllycaconitine citrate

    CAS:
    <p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>
    Formula:C43H58N2O17
    Purity:98.03% - 98.91%
    Color and Shape:Solid
    Molecular weight:874.92

    Ref: TM-T12017

  • Methylatropine (nitrate)
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    Methylatropine (nitrate)

    CAS:
    <p>Methylatropine: Muscarinic antagonist, &lt;0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>
    Formula:C18H26N2O6
    Color and Shape:Solid
    Molecular weight:366.414

    Ref: TM-T36204

  • Encecalinol
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    Encecalinol

    CAS:
    <p>Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].</p>
    Formula:C14H18O3
    Color and Shape:Solid
    Molecular weight:234.29

    Ref: TM-T82472

  • nAChR agonist CMPI hydrochloride
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    nAChR agonist CMPI hydrochloride

    CAS:
    <p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>
    Formula:C18H20Cl2N4O
    Color and Shape:Solid
    Molecular weight:379.29

    Ref: TM-T39771

  • Multitarget AD inhibitor-1
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    Multitarget AD inhibitor-1

    CAS:
    <p>Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.</p>
    Formula:C29H38N2O
    Color and Shape:Solid
    Molecular weight:430.636

    Ref: TM-T39678

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    CUR-IPA

    <p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>
    Formula:C43H38N2O8
    Color and Shape:Solid
    Molecular weight:710.77

    Ref: TM-T205484

  • 4-Bromo-2,5-DMMA
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    4-Bromo-2,5-DMMA

    CAS:
    <p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>
    Formula:C12H18BrNO2
    Color and Shape:Solid
    Molecular weight:288.18

    Ref: TM-T203247

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    Anticonvulsant agent 9

    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Formula:C22H24N4O2
    Color and Shape:Solid
    Molecular weight:376.45

    Ref: TM-T205256

  • CymitQuimica logo
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    5-HT1AR/5-HT6R ligand-1

    <p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>
    Formula:C25H29ClN4O2S
    Color and Shape:Solid
    Molecular weight:485.04

    Ref: TM-T205634

  • GSK-3β inhibitor 27
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    GSK-3β inhibitor 27

    <p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>
    Formula:C16H17ClN4O2
    Color and Shape:Solid
    Molecular weight:332.79

    Ref: TM-T207246

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    AChE/BChE-IN-14

    <p>AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both</p>
    Formula:C19H23NO3
    Color and Shape:Solid
    Molecular weight:313.39

    Ref: TM-T79966

  • Fluphenazine-N-2-chloroethane (hydrochloride)
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    Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Formula:C22H27Cl3F3N3S
    Color and Shape:Solid
    Molecular weight:528.89

    Ref: TM-T36820

  • γ-Secretase modulator 10
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    γ-Secretase modulator 10

    CAS:
    <p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>
    Formula:C25H23F3N4O2
    Color and Shape:Solid
    Molecular weight:468.48

    Ref: TM-T40315

  • MGS0274
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    MGS0274

    CAS:
    <p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>
    Formula:C21H32FNO7
    Color and Shape:Solid
    Molecular weight:429.485

    Ref: TM-T38990

  • Vortioxetine D8
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    Vortioxetine D8

    CAS:
    <p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors &amp; SERT (Ki: 15-1.6 nM).</p>
    Formula:C18H22N2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:306.5

    Ref: TM-T13308

  • Brexpiprazole S-oxide D8
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    Brexpiprazole S-oxide D8

    CAS:
    <p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>
    Formula:C25H19D8N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:457.61

    Ref: TM-T10611

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    AChE-IN-45

    <p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>
    Color and Shape:Odour Solid

    Ref: TM-T83183