Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,022 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
Show 12 more subcategories
Found 5548 products of "Neuroscience"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BACE1-IN-4
CAS:BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.Formula:C21H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.57Jimscaline
CAS:Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.295LY3020371 hydrochloride
CAS:LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.Formula:C15H16ClF2NO5SColor and Shape:SolidMolecular weight:395.81AChE-IN-79
AChE-IN-79 (compound 3i) is an acetylcholinesterase inhibitor with an IC50 of 2.7 µM, suitable for studies related to Alzheimer's disease.Formula:C29H27NO6SColor and Shape:SolidMolecular weight:517.59Etoperidone
CAS:Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).Formula:C19H28ClN5OColor and Shape:SolidMolecular weight:377.91Tipindole
CAS:Tipindole is a serotonin antagonist utilized in research related to depression.Formula:C16H20N2O2SColor and Shape:SolidMolecular weight:304.41Norneostigmine
CAS:Norneostigmine is a potent inhibitor of AChE capable of crossing the blood-brain barrier. When administered to mice, it achieves a 50% inhibition rate of brain AChE activity within 10 minutes, comparable to the effect of Tetrahydroaminoacridine (57% inhibition in 10 minutes). Norneostigmine is applicable in research on Alzheimer's disease and other memory-related disorders.Formula:C11H16N2O2Color and Shape:SolidMolecular weight:208.261,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5RO-1-5237
CAS:RO-1-5237, a cholinergic compound and a metabolic product of Pyridostigmine Bromide, is utilized in research for myasthenia gravis.Formula:C6H8BrNOColor and Shape:SolidMolecular weight:190.04BGT1-IN-1
CAS:BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.Formula:C6H9NO2Color and Shape:SolidMolecular weight:127.14MAO-B-IN-44
CAS:MAO-B-IN-44 (Compound 4n) is a selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.01 μM, demonstrating weak inhibition of MAO-A (IC50=14.4 μM). It reduces the degradation of neurotransmitters like dopamine and holds potential for research into neurodegenerative diseases such as Parkinson's disease, which are associated with MAO-B abnormalities.Formula:C34H32N4O8Color and Shape:SolidMolecular weight:624.64Aβ42 agonist-1
CAS:Aβ42 agonist-1 is a small molecule compound with anti-cancer activity and NF-κB inhibitory properties, inducing Aβ42 aggregation.Formula:C15H11NO2Purity:99.77%Color and Shape:SolidMolecular weight:237.25Nedemelteon
CAS:Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).Formula:C15H18N2O2Color and Shape:SolidMolecular weight:258.32Aβ-IN-2
Aβ-IN-2 is a peptide inhibitor of Aβ1-42.Formula:C37H51NOColor and Shape:SolidMolecular weight:525.81DA-8031
CAS:DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).Formula:C21H24N2O2Color and Shape:SolidMolecular weight:336.43PF-06648671
CAS:PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.Formula:C25H23ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:538.92(-)-5-HT2C agonist-3
CAS:Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.Formula:C19H23ClFNO2Color and Shape:SolidMolecular weight:351.8425C-NBF hydrochloride
CAS:25C-NBF hydrochloride is an agonist of 5-HT receptors, specifically activating 5-HT2A and 5-HT2C receptors, with an EC50 of approximately 0.3 μM.Formula:C17H20Cl2FNO2Molecular weight:360.251β-Secretase Inhibitor III
β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.Formula:C20H20F2N4O3SColor and Shape:SolidMolecular weight:434.46SEP-363856 mesylate
CAS:SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.Formula:C10H17NO4S2Color and Shape:SolidMolecular weight:279.38RTIOXA-43
CAS:RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.Formula:C37H37N5O5SPurity:99.17%Color and Shape:SolidMolecular weight:663.79Ref: TM-T87345
1mg210.00€5mg516.00€10mg833.00€25mg1,607.00€50mg2,582.00€100mg3,492.00€1mL*10mM (DMSO)754.00€AChE-IN-25
AChE-IN-25: selective, potent AChE inhibitor, non-competitive, IC50 = 2.95 μM, for Alzheimer's research.Formula:C20H15ClN4O4SColor and Shape:SolidMolecular weight:442.88Nafimidone hydrochloride
CAS:Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.Formula:C15H13ClN2OColor and Shape:SolidMolecular weight:272.73Zanapezil fumarate
CAS:Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.Formula:C29H36N2O5Color and Shape:SolidMolecular weight:492.61BChE-IN-2
BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.Formula:C22H31N5Color and Shape:SolidMolecular weight:365.52CEase-IN-1
CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.Formula:C13H15F3N2O2Color and Shape:SolidMolecular weight:288.27Geissoschizoline
CAS:Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42UB 165
CAS:Subtype-selective nicotinic agonistFormula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.72BChE-IN-5
BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.Formula:C30H42N4OColor and Shape:SolidMolecular weight:474.68PXS-4787 hydrochloride
CAS:PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.Formula:C10H13ClFNO2SColor and Shape:SolidMolecular weight:265.73ChEs/MAOs-IN-2
CAS:ChEs/MAOs-IN-2 (compound a11) serves as an inhibitor for both cholinesterases and monoamine oxidases, exhibiting IC 50 values of 0.10 µM for MAO-A, 0.20 µM for MAO-B, 0.30 µM for AChE, and 0.40 µM for BChE. This compound shows promise for Alzheimer's disease research [1].Formula:C15H12N2O3SColor and Shape:SolidMolecular weight:300.33SNRI-IN-1
CAS:SNRI-IN-1 (Compound 7a) acts as a dual inhibitor of serotonin and noradrenaline monoamine reuptake, with a P-glycoprotein Efflux Ratio of 20 [1].Formula:C16H20Cl2N2O2Color and Shape:SolidMolecular weight:343.25MAO-A inhibitor 1
CAS:MAO-A Inhibitor 1 (compound VIII) acts as a MAO-A inhibitor and exhibits an IC50 value of 100 μM [1].Formula:C14H12O4Color and Shape:SolidMolecular weight:244.24LRRK2-IN-6
LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).Formula:C23H24F2N4O2SColor and Shape:SolidMolecular weight:458.52AAZ-A 154 mesylate
CAS:AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.Formula:C15H24N2O4SColor and Shape:SolidMolecular weight:328.43AAZ-A 154 hydrochloride
CAS:AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formula:C14H21ClN2OColor and Shape:SolidMolecular weight:268.78YM-202074
CAS:YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).Formula:C22H30N4O2SColor and Shape:SolidMolecular weight:414.56BChE-IN-3
BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.Formula:C26H41N3O2Color and Shape:SolidMolecular weight:427.62ChE/Aβ1-42-IN-1
ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.Formula:C19H24N2O3Color and Shape:SolidMolecular weight:328.41PF470
CAS:PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.Formula:C18H16N6OColor and Shape:SolidMolecular weight:332.36QP5020
CAS:QP5020 is a QPCTL inhibitor with an IC50 value of 15 nM, demonstrating antitumor efficacy.Formula:C20H19FN6Molecular weight:362.40MAO-B-IN-28
CAS:MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 value of 1.9±0.5 nM, potentially serving as a candidate molecule for neurodegenerative disease research.Formula:C19H10F3NO4SMolecular weight:405.35AChE-IN-22
AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.Formula:C21H20N4O5SColor and Shape:SolidMolecular weight:440.475-HT1A antagonist 1
Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.Formula:C23H29ClN6O2Color and Shape:SolidMolecular weight:456.97LRRK2-IN-12
CAS:LRRK2-IN-12 (compound 1) is a potent inhibitor of LRRK2 (G20195) with an IC 50 of 0.45 nM, LRRK2 WT with an IC 50 of 1.1 nM, and LRRK2 WT ADP-Glo with an IC 50 of 0.46 nM. This compound is utilized in research related to Alzheimer's Disease [1].Formula:C18H17ClN8O2Color and Shape:SolidMolecular weight:412.83CaMKK2-IN-1
CAS:CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.Formula:C22H22N2O3Molecular weight:362.42β-CCM
CAS:β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and convulsant effects. It enhances emotional reactivity and reduces interference sensitivity in spatial working memory tasks. β-CCM is applicable in research related to anxiety disorders.Formula:C13H10N2O2Color and Shape:SolidMolecular weight:226.231MAO-B-IN-5
CAS:MAO-B-IN-5: potent, selective oral MAO-B inhibitor, IC50=0.204μM, potential for Parkinson's research.
Formula:C19H21FN2O2Purity:97.68%Color and Shape:SolidMolecular weight:328.38Azotomycin
CAS:Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.Formula:C17H23N7O8Purity:98%Color and Shape:SolidMolecular weight:453.41AAZ-A 154 benzoate
CAS:AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44
