Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(942 products)
- ACK(1 products)
- AChR(576 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,949 products)
- BACE(36 products)
- Beta Amyloid(205 products)
- CaMK(69 products)
- Cyclooxygenase (COX) Inhibitors(565 products)
- Dopamine Receptor(410 products)
- GABA Receptor(337 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(359 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(26 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
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Found 5389 products of "Neuroscience"
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BuChE-IN-21
<p>BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.</p>Formula:C16H23NO2Color and Shape:SolidMolecular weight:261.17288R-(+)-Cotinine
CAS:<p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>Formula:C10H12N2OColor and Shape:SolidMolecular weight:176.22β-Amyloid (1-17)
CAS:<p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>Formula:C90H130N28O29Purity:98%Color and Shape:SolidMolecular weight:2068.2VVZ-149
<p>VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.</p>Color and Shape:SolidPSEN1-IN-1
<p>PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50</p>Formula:C20H19ClF3NO3SColor and Shape:SolidMolecular weight:445.88Salvianolic acid H
CAS:<p>Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].</p>Formula:C27H22O12Color and Shape:SolidMolecular weight:538.46LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.34(-)-Eseroline fumarate
CAS:<p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>Formula:C17H22N2O5Color and Shape:SolidMolecular weight:334.37Aβ-IN-8
<p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>Formula:C22H16F3N3O3SColor and Shape:SolidMolecular weight:459.44hAChE-IN-4
<p>Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study of</p>Formula:C30H23Cl3N2O3Color and Shape:SolidMolecular weight:565.87AChE-IN-34
<p>AChE-IN-34 (compound 5l) is a potent, selective AChE inhibitor exhibiting an IC50 of 3.98 µM and negligible BChE inhibition.</p>Formula:C19H14N8O6Color and Shape:SolidMolecular weight:450.36AChE-IN-39
<p>AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to</p>Formula:C19H15NO3Color and Shape:SolidMolecular weight:305.33OXA(17-33) TFA
<p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>Formula:C81H126F3N23O24Color and Shape:SolidMolecular weight:1863mGluR3 modulator-1
CAS:<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Formula:C16H21N3OPurity:98.99%Color and Shape:SolidMolecular weight:271.36KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formula:C22H12F3N5Na2O7Purity:97.27%Color and Shape:SoildMolecular weight:561.33BuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Color and Shape:Odour SolidOM99-2
CAS:<p>OM99-2, an 8-residue peptidomimetic, binds memapsin 2 with 9.58 nM Ki; promising for Alzheimer's research.</p>Formula:C41H64N8O14Color and Shape:SolidMolecular weight:893.005β-Amyloid (1-38), mouse, rat
CAS:<p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>Color and Shape:Solid(D-Asp1)-Amyloid β-Protein (1-42)
CAS:<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Formula:C203H311N55O60SColor and Shape:SolidMolecular weight:4514.04TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formula:C169H303N69O43Color and Shape:SolidMolecular weight:3989.65α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formula:C60H94N14O16Color and Shape:SolidMolecular weight:1267.47Aloveroside A
CAS:<p>Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstrating</p>Formula:C30H40O17Color and Shape:SolidMolecular weight:672.635β-Cholanic acid
CAS:<p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>Formula:C24H40O2Purity:98.91% - 99.89%Color and Shape:SoildMolecular weight:360.57Pozanicline hydrochloride
<p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>Formula:C11H17ClN2OPurity:97.13% - 99.81%Color and Shape:SolidMolecular weight:228.72(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Formula:C15H23NO2SPurity:98.19%Color and Shape:SoildMolecular weight:281.41Apoptosis Compound Library
<p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>Color and Shape:Odour SolidMinesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Formula:C21H31ClN4O5Purity:99.85% - 99.88%Color and Shape:SolidMolecular weight:454.95Serotonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;</p>Color and Shape:Odour SolidDavunetide acetate
<p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>Formula:C38H64N10O14Purity:99.52% - 99.78%Color and Shape:SolidMolecular weight:884.97Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Color and Shape:Odour SolidNeocarzinostatin
CAS:<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Purity:98%Color and Shape:SolidMolecular weight:N/AStacofylline
CAS:<p>Stacofylline is a xanthine derivative that is used to treat migraine headaches.</p>Formula:C20H33N7O3Purity:99.54% - >99.99%Color and Shape:SolidMolecular weight:419.52Mant-GTPγS
CAS:<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Formula:C18H23N6O14P3SColor and Shape:SolidMolecular weight:672.39Osmanthuside B
CAS:<p>Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.</p>Formula:C29H36O13Color and Shape:SolidMolecular weight:592.59Bensultap
CAS:Bensultap is an agricultural chemical typically used as a pesticide.Formula:C17H21NO4S4Purity:98%Color and Shape:SolidMolecular weight:431.61FFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Formula:C15H13FN2OPurity:98%Color and Shape:SolidMolecular weight:256.27Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formula:C12H4Cl2F6N4O2SPurity:98%Color and Shape:SolidMolecular weight:453.14GRGDSPK acetate
CAS:<p>GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.</p>Formula:C30H53N11O13Purity:97.9%Color and Shape:SoildMolecular weight:775.81Arisugacin G
CAS:Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).Formula:C27H32O5Color and Shape:SolidMolecular weight:436.54Zanapezil free base
CAS:<p>Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.</p>Formula:C25H32N2OColor and Shape:SolidMolecular weight:376.544β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Formula:C73H118N16O27Purity:98%Color and Shape:SolidMolecular weight:1651.815-AAM-2-CP
CAS:<p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>Formula:C8H9ClN2OPurity:99.58%Color and Shape:SolidMolecular weight:184.62Guanylyl Imidodiphosphate (lithium salt)
CAS:<p>Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.</p>Formula:C10H13Li4N6O13P3Color and Shape:SolidMolecular weight:545.93BU 226 hydrochloride
CAS:<p>BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM.</p>Formula:C12H12ClN3Purity:99.67%Color and Shape:SolidMolecular weight:233.7LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58LP 12 hydrochloride
CAS:<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formula:C32H40ClN3OColor and Shape:SolidMolecular weight:518.14AChE/BuChE-IN-6
<p>AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.</p>Formula:C24H20ClN3O3Color and Shape:SolidMolecular weight:433.887β-Amyloid (29-40)
CAS:<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formula:C49H88N12O13SPurity:98%Color and Shape:SolidMolecular weight:1085.36AChE-IN-36
<p>AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].</p>Formula:C25H21ClO5SColor and Shape:SolidMolecular weight:468.95Tabernanthalog
CAS:<p>TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.</p>Formula:C14H18N2OPurity:99.82% - 99.89%Color and Shape:SoildMolecular weight:230.31
