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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5390 products of "Neuroscience"

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  • Octamylamine
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    Octamylamine

    CAS:
    <p>Octamylamine is a bioactive chemical.</p>
    Formula:C13H29N
    Color and Shape:Solid
    Molecular weight:199.3761

    Ref: TM-T33778

  • α-Conotoxin imi
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    α-Conotoxin imi

    CAS:
    alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.
    Formula:C52H78N20O15S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1351.56

    Ref: TM-T23707

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    DISC-0974

    <p>DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.</p>
    Color and Shape:Liquid
    Molecular weight:145.5kDa

    Ref: TM-T77396

  • Fluphenazine-N-2-chloroethane (hydrochloride)
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    Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Formula:C22H27Cl3F3N3S
    Color and Shape:Solid
    Molecular weight:528.89

    Ref: TM-T36820

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    GABAA receptor modulator-3

    <p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>
    Formula:C18H22O2
    Color and Shape:Solid
    Molecular weight:270.37

    Ref: TM-T205029

  • HTR2A antagonist 1
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    HTR2A antagonist 1

    <p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>
    Formula:C35H43Cl2F2N5O4
    Color and Shape:Solid
    Molecular weight:706.65

    Ref: TM-T204966

  • Cloxacepride
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    Cloxacepride

    CAS:
    <p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>
    Formula:C22H27Cl2N3O4
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:468.37

    Ref: TM-T68048

  • β-Amyloid (10-20)
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    β-Amyloid (10-20)

    CAS:
    Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-
    Formula:C71H99N17O16
    Purity:98%
    Color and Shape:Lyophilized Powder
    Molecular weight:1446.65

    Ref: TM-TP1786

  • Anisatin
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    Anisatin

    <p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>
    Formula:C15H20O8
    Color and Shape:Solid
    Molecular weight:328.317

    Ref: TM-T124719

  • Duloxetine D3 hydrochloride
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    Duloxetine D3 hydrochloride

    CAS:
    <p>Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.</p>
    Formula:C18H20ClNOS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.89

    Ref: TM-T11113

  • (+)-Coclaurine hydrochloride
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    (+)-Coclaurine hydrochloride

    CAS:
    <p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>
    Formula:C17H20ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.8

    Ref: TM-T78539

  • MK-0969
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    MK-0969

    CAS:
    <p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>
    Formula:C24H30F2N4O2
    Color and Shape:Solid
    Molecular weight:444.52

    Ref: TM-T33425

  • MGS0028
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    MGS0028

    CAS:
    <p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>
    Formula:C8H8FNO5
    Color and Shape:Solid
    Molecular weight:217.15

    Ref: TM-T28033

  • 5-HT2A receptor agonist-5
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    5-HT2A receptor agonist-5

    CAS:
    <p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>
    Formula:C23H29N3O
    Color and Shape:Solid
    Molecular weight:363.5

    Ref: TM-T203649

  • AChE/MAO-B-IN-7
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    AChE/MAO-B-IN-7

    <p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>
    Formula:C22H21N3O3
    Color and Shape:Solid
    Molecular weight:375.42

    Ref: TM-T204841

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    BuChE-IN-21

    <p>BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.</p>
    Formula:C16H23NO2
    Color and Shape:Solid
    Molecular weight:261.17288

    Ref: TM-T207403

  • Brexpiprazole S-oxide D8
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    Brexpiprazole S-oxide D8

    CAS:
    <p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>
    Formula:C25H19D8N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:457.61

    Ref: TM-T10611

  • Vortioxetine D8
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    Vortioxetine D8

    CAS:
    <p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors &amp; SERT (Ki: 15-1.6 nM).</p>
    Formula:C18H22N2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:306.5

    Ref: TM-T13308

  • β-Amyloid (11-22)
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    β-Amyloid (11-22)

    CAS:
    β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s
    Formula:C70H102N18O18
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1483.67

    Ref: TM-TP1673

  • M 8218
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    M 8218

    CAS:
    <p>M 8218 is a bioactive chemical.</p>
    Formula:C20H29NO2
    Color and Shape:Solid
    Molecular weight:315.45

    Ref: TM-T33111

  • 2-Methyl-1-indanone
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    2-Methyl-1-indanone

    CAS:
    <p>2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.</p>
    Formula:C10H10O
    Purity:96.6%
    Color and Shape:Solid
    Molecular weight:146.19

    Ref: TM-TN9417

  • Cannabidiolic acid methyl ester
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    Cannabidiolic acid methyl ester

    CAS:
    <p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>
    Formula:C23H32O4
    Color and Shape:Solid
    Molecular weight:372.5

    Ref: TM-T203571

  • β-Amyloid (35-42)
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    β-Amyloid (35-42)

    CAS:
    <p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>
    Formula:C33H60N8O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:744.94

    Ref: TM-TP1586

  • Laniquidar TFA
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    Laniquidar TFA

    <p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>
    Formula:C39H37F3N4O5
    Purity:99.85%
    Color and Shape:Soild
    Molecular weight:698.73

    Ref: TM-T64133L

  • Sintamil
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    Sintamil

    CAS:
    <p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>
    Formula:C18H20ClN3O4
    Color and Shape:Solid
    Molecular weight:377.82

    Ref: TM-T71697

  • SSAO inhibitor-1
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    SSAO inhibitor-1

    CAS:
    <p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>
    Formula:C17H24FN5O2
    Color and Shape:Solid
    Molecular weight:349.41

    Ref: TM-T39741

  • p-HTAA
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    p-HTAA

    CAS:
    <p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>
    Formula:C24H16O4S5
    Color and Shape:Solid
    Molecular weight:528.71

    Ref: TM-T74711

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    5-HT6R antagonist 6

    <p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>
    Formula:C24H26N4O2S
    Color and Shape:Solid
    Molecular weight:434.55

    Ref: TM-T205194

  • BACE1-IN-6
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    BACE1-IN-6

    CAS:
    <p>BACE1-IN-6 is a BACE1 inhibitor with an IC 50 value of 1.5 nM.</p>
    Formula:C25H23F2N5O2S
    Color and Shape:Solid
    Molecular weight:495.55

    Ref: TM-T39484

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    GABAA receptor modulator-4

    <p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>
    Formula:C15H17BrO4S
    Color and Shape:Solid
    Molecular weight:373.26

    Ref: TM-T205164

  • SB656104
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    SB656104

    CAS:
    <p>SB656104 is a bioactive chemical.</p>
    Formula:C25H30ClN3O3S
    Color and Shape:Solid
    Molecular weight:488.04

    Ref: TM-T34546

  • epi-Aszonalenin A
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    epi-Aszonalenin A

    CAS:
    <p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>
    Formula:C25H25N3O3
    Color and Shape:Solid
    Molecular weight:415.48

    Ref: TM-T74056

  • YS-370
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    YS-370

    CAS:
    <p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>
    Formula:C37H35BrN4O3
    Purity:98.055%
    Color and Shape:Solid
    Molecular weight:663.6

    Ref: TM-T60009

  • FRM-024
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    FRM-024

    CAS:
    <p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>
    Formula:C22H22ClN5O2
    Color and Shape:Solid
    Molecular weight:423.9

    Ref: TM-T39492

  • Blestrin D
    Targetmol
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    Blestrin D

    CAS:
    <p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>
    Formula:C30H24O6
    Color and Shape:Solid
    Molecular weight:480.51

    Ref: TM-T75514

  • Jatrorrhizine hydroxide
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    Jatrorrhizine hydroxide

    CAS:
    <p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>
    Formula:C20H21NO5
    Color and Shape:Solid
    Molecular weight:355.38

    Ref: TM-T75436

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    5-HT5AR/5-HT6R ligand-1

    <p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>
    Formula:C25H30N4O2S
    Color and Shape:Solid
    Molecular weight:450.6

    Ref: TM-T205096

  • N-Desmethyl Pimavanserin
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    N-Desmethyl Pimavanserin

    CAS:
    <p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>
    Formula:C24H32FN3O2
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:413.53

    Ref: TM-T37979

  • α-Conotoxin PIA
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    α-Conotoxin PIA

    CAS:
    <p>Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM</p>
    Formula:C79H125N27O25S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1981.3

    Ref: TM-TP2065

  • Cianopramine hydrochloride
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    Cianopramine hydrochloride

    CAS:
    <p>Cianopramine hydrochloride is a bio-active chemical.</p>
    Formula:C20H24ClN3
    Color and Shape:Solid
    Molecular weight:341.88

    Ref: TM-T30929

  • Lupanine hydrochloride
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    Lupanine hydrochloride

    CAS:
    <p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>
    Formula:C15H25ClN2O
    Color and Shape:Solid
    Molecular weight:284.83

    Ref: TM-T75644

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    JF-NP-26

    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Color and Shape:Solid

    Ref: TM-T38229

  • Calmodulin-Dependent Protein Kinase II 290-309 acetate
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    Calmodulin-Dependent Protein Kinase II 290-309 acetate

    <p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>
    Formula:C105H189N31O26S
    Purity:96.7%
    Color and Shape:Solid
    Molecular weight:2333.88

    Ref: TM-TP1271L

  • LY 293284
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    LY 293284

    CAS:
    <p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>
    Formula:C19H26N2O
    Color and Shape:Solid
    Molecular weight:298.42

    Ref: TM-T27914

  • Nardoguaianone J
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    Nardoguaianone J

    CAS:
    <p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>
    Formula:C15H22O2
    Color and Shape:Solid
    Molecular weight:234.33

    Ref: TM-T75530

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    XL01126

    XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.
    Formula:C50H64ClFN10O6S2
    Color and Shape:Solid
    Molecular weight:1019.69

    Ref: TM-T74638

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    I2-IRs ligand-1

    <p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>
    Formula:C21H23ClFN2O4P
    Color and Shape:Solid
    Molecular weight:452.84

    Ref: TM-T205115

  • VU6028418
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    VU6028418

    CAS:
    <p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>
    Color and Shape:Solid

    Ref: TM-T71675

  • Zicronapine fumarate
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    Zicronapine fumarate

    CAS:
    <p>Zicronapine fumarate, an antipsychotic, targets D1/D2 &amp; 5-HT2A receptors; may treat neuropsychiatric conditions.</p>
    Formula:C26H31ClN2O4
    Color and Shape:Solid
    Molecular weight:470.99

    Ref: TM-T74668

  • Cyclodrine
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    Cyclodrine

    CAS:
    <p>Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.</p>
    Formula:C19H29NO3
    Purity:97.62%
    Color and Shape:Soild
    Molecular weight:319.44

    Ref: TM-T10914L