Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(643 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,006 products)
- BACE(37 products)
- Beta Amyloid(222 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(598 products)
- Dopamine Receptor(445 products)
- GABA Receptor(371 products)
- Gamma-secretase(60 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(326 products)
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Found 5477 products of "Neuroscience"
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Naratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Formula:C17H26ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:374.94Cyclodrine
CAS:Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.Formula:C19H29NO3Purity:97.62%Color and Shape:SoildMolecular weight:319.44Ref: TM-T10914L
1mg73.00€5mg149.00€10mg212.00€25mg319.00€50mg447.00€100mg610.00€200mg822.00€1mL*10mM (DMSO)148.00€XL01126
XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.Formula:C50H64ClFN10O6S2Color and Shape:SolidMolecular weight:1019.69α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFormula:C79H125N27O25S4Purity:98%Color and Shape:SolidMolecular weight:1981.32-Methyl-1-indanone
CAS:2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.Formula:C10H10OPurity:96.6%Color and Shape:SolidMolecular weight:146.19M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.45β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormula:C70H102N18O18Purity:98%Color and Shape:SolidMolecular weight:1483.67MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.151H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。
Formula:C26H34N2O7Purity:99.44%Color and Shape:SoildMolecular weight:486.56Duloxetine D3 hydrochloride
CAS:Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.Formula:C18H20ClNOSPurity:98%Color and Shape:SolidMolecular weight:336.89α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purity:98%Color and Shape:SolidMolecular weight:1351.56UCM 549
CAS:UCM 549 is a bioactive chemical.Formula:C19H21NO2Color and Shape:SolidMolecular weight:295.38AC3-I, myristoylated
Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).
Formula:C78H137N21O20Purity:98%Color and Shape:SolidMolecular weight:1689.05(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formula:C6H10BrNO2Purity:98%Color and Shape:SolidMolecular weight:208.05Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Eletriptan
CAS:Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.Formula:C22H26N2O2SColor and Shape:SolidMolecular weight:382.52MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formula:C295H455N95O97S10Purity:98%Color and Shape:SolidMolecular weight:7205CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Formula:C54H58Cl2N10O11Purity:98%Color and Shape:SolidMolecular weight:1094MAO-B-IN-4
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.Formula:C23H20ClF2N3Purity:98%Color and Shape:SolidMolecular weight:411.87Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificityFormula:C18H18N2O3Purity:98%Color and Shape:SolidMolecular weight:310.35α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Formula:C156H275N47O43Purity:98%Color and Shape:SolidMolecular weight:3497.14PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Purity:98%Color and Shape:Odour SolidMAO-B-IN-3
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a KiFormula:C24H25N3O2Purity:98%Color and Shape:SolidMolecular weight:387.472'-O-Succinyl-cAMP
CAS:2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2Formula:C14H16N5O9PColor and Shape:SolidMolecular weight:429.282MAO-B-IN-18
MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A.Formula:C25H22N4O5Purity:98%Color and Shape:SolidMolecular weight:458.47MAO-B-IN-24
MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM.Formula:C20H18N2OPurity:98%Color and Shape:SolidMolecular weight:302.37Xanthohumol I
Xanthohumol I is a natural product that can be used as a reference standard.Formula:C21H22O6Color and Shape:SolidMolecular weight:370.401hAChE-IN-3
hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,Formula:C30H24ClN3O5Purity:98%Color and Shape:SolidMolecular weight:541.98JPC0323
JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequateFormula:C22H43NO4Purity:98%Color and Shape:SolidMolecular weight:385.58Tranylcypromine
CAS:Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.Formula:C9H11NPurity:98%Color and Shape:SolidMolecular weight:133.19(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Formula:C22H32ClNO2Color and Shape:SolidMolecular weight:377.95AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electricFormula:C18H19BrN2O2Color and Shape:SolidMolecular weight:375.265-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.04CUR-IPA
CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.Formula:C43H38N2O8Color and Shape:SolidMolecular weight:710.77Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45BMY-14802
CAS:BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formula:C18H22F2N4OPurity:99.84%Color and Shape:SoildMolecular weight:348.39Ref: TM-T67739
2mg35.00€5mg52.00€10mg90.00€25mg164.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€AChE-IN-27
CAS:AChE-IN-27 is a small molecule used for high-throughput assays.Formula:C20H14N2O3Purity:98.54%Color and Shape:SolidMolecular weight:330.34(Rac)-Sclerone
CAS:(Rac)-Sclerone, a natural product isolated from the green husk of Carya illinoinensis, exhibits significant AChE inhibition activity with an IC50 value of 192.Formula:C10H10O3Color and Shape:SolidMolecular weight:178.18Peptide 401
CAS:Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.Formula:C110H192N40O24S4Purity:98%Color and Shape:SolidMolecular weight:2587.22BuChE-IN-8
BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) andFormula:C28H33ClN4O2SColor and Shape:SolidMolecular weight:525.11Cytidine 5′-diphosphoethanolamine
CAS:Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].
Formula:C11H20N4O11P2Color and Shape:SolidMolecular weight:446.24hAChE-IN-6
hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM.Color and Shape:Odour SolidPD25
PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.Formula:C25H24N2O4Color and Shape:SolidMolecular weight:416.47Lycoramine hydrobromide
CAS:Lycoramine is a natural alkaloid isolated from Lycoris chinensis.Formula:C17H24BrNO3Color and Shape:SolidMolecular weight:370.28Muscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20NO2Purity:98%Color and Shape:SolidMolecular weight:174.26TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.36p-Xylene bis(pyridinium bromide)
CAS:p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.Formula:C18H18Br2N2Color and Shape:SolidMolecular weight:422.16Cinazepam
CAS:Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Formula:C19H14BrClN2O5Color and Shape:SolidMolecular weight:465.68
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