Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 562 products of "Cyclooxygenase (COX) Inhibitors"
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Pranoprofen
CAS:Formula:C15H13NO3Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:255.27Imatinib Mesylate
CAS:Formula:C29H31N7O·CH4O3SPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:589.722-Hydroxy Ibuprofen
CAS:<p>2-Hydroxy Ibuprofen is a metabolite of ibuprofen, applicable in biochemical experiments and drug synthesis research. Ibuprofen inhibits both COX-1 and COX-2.</p>Formula:C13H18O3Color and Shape:SolidMolecular weight:222.28(S)-Ketorolac
CAS:<p>(S)-Ketorolac is a potent inhibitor of COX1 and COX2 enzyme, and is nonsteroidal anti-inflammatory agent.</p>Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27Betamethasone Valerate
CAS:Formula:C27H37FO6Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:476.59Nimesulide D5
CAS:<p>Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM)</p>Formula:C13H12N2O5SPurity:98%Color and Shape:SolidMolecular weight:313.34Parecoxib
CAS:Formula:C19H18N2O4SPurity:>97.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:370.42Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Formula:C20H20ClN3O3Purity:99.94%Color and Shape:SolidMolecular weight:385.84Tiaprofenic acid
CAS:<p>Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.</p>Formula:C14H12O3SPurity:99.51%Color and Shape:SolidMolecular weight:260.31Macelignan
CAS:<p>Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus.</p>Formula:C20H24O4Purity:98.01% - >99.99%Color and Shape:SolidMolecular weight:328.4anemarsaponin B
CAS:<p>Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity</p>Formula:C45H74O18Purity:99.06% - 99.81%Color and Shape:SolidMolecular weight:903.06Hexahydrocurcumin
CAS:<p>Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.</p>Formula:C21H26O6Purity:99.43% - 99.88%Color and Shape:SolidMolecular weight:374.43Dehydroevodiamine
CAS:<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Formula:C19H15N3OPurity:99.54%Color and Shape:SolidMolecular weight:301.34Rebamipide mofetil
CAS:<p>Rebamipide mofetil is an orally active prodrug of Rebamipide which is a mucoprotective agent.</p>Formula:C25H26ClN3O5Purity:98.17%Color and Shape:SolidMolecular weight:483.94Metyrosine
CAS:<p>Metyrosine: antihypertensive, tyrosine hydroxylase inhibitor, controls COX-2, lowers blood pressure.</p>Formula:C10H13NO3Purity:98.68% - 99.72%Color and Shape:SolidMolecular weight:195.22Ginsenoside Rg5
CAS:<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Formula:C42H70O12Purity:98% - 99.65%Color and Shape:SolidMolecular weight:767γ-Tocopherol
CAS:<p>(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.</p>Formula:C28H48O2Purity:99.31% - 99.39%Color and Shape:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightMolecular weight:416.68Iguratimod
CAS:<p>Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits MIF (IC50: 6.81 μM).</p>Formula:C17H14N2O6SPurity:99.93%Color and Shape:White PowderMolecular weight:374.37Tolmetin sodium
CAS:<p>Tolmetin sodium is an NSAID, orally active COX inhibitor with IC50 of 0.35 μM (COX-1) and 0.82 μM (COX-2).</p>Formula:C15H14NNaO3Color and Shape:SolidMolecular weight:279.271Ampiroxicam
CAS:<p>Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.</p>Formula:C20H21N3O7SPurity:97.27% - 99.2%Color and Shape:PowderMolecular weight:447.46Bromfenac
CAS:<p>Bromfenac, a potent COX inhibitor, targets ocular inflammation with IC50s of 5.56 nM for COX-1 and 7.45 nM for COX-2.</p>Formula:C15H12BrNO3Color and Shape:SolidMolecular weight:334.16Zaltoprofen
CAS:<p>Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.</p>Formula:C17H14O3SPurity:99.72%Color and Shape:Off-White To Pale Yellow Crystalline SolidMolecular weight:298.36α-Humulene
CAS:<p>α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory</p>Formula:C15H24Purity:97.18% - 97.18%Color and Shape:LiquidMolecular weight:204.35Ginsenoside Rd
CAS:<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Formula:C48H82O18Purity:99.13% - 99.92%Color and Shape:SolidMolecular weight:947.15(±)-Catechin
CAS:<p>(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.</p>Formula:C15H14O6Purity:98.46%Color and Shape:White To Yellow PowderMolecular weight:290.27Mavacoxib
CAS:<p>Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.</p>Formula:C16H11F4N3O2SPurity:99.90%Color and Shape:SolidMolecular weight:385.34Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Formula:C22H28ClNO5Purity:98.82%Color and Shape:SolidMolecular weight:421.91Tolmetin sodium dihydrate
CAS:<p>Tolmetin sodium dihydrate is an oral NSAID inhibiting COX-1 and COX-2, widely used in studies of prostaglandin synthesis and anti-inflammatory mechanisms.</p>Formula:C15H18NNaO5Purity:99.57%Color and Shape:Crystalline SolidMolecular weight:315.3Bromfenac Sodium
CAS:<p>Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID) and an orally available COX inhibitor, which has anti-inflammatory activity.</p>Formula:C15H11BrNO3·NaPurity:99.93%Color and Shape:SolidMolecular weight:356.15Regaloside B
CAS:<p>Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric</p>Formula:C20H26O11Purity:99.4% - 99.57%Color and Shape:SolidMolecular weight:442.41α-Demethylnaproxen
CAS:<p>α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)</p>Formula:C13H12O3Purity:97.57%Color and Shape:Off-White SolidMolecular weight:216.23FR 122047
CAS:<p>FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM</p>Formula:C23H26ClN3O3SPurity:99.93%Color and Shape:SolidMolecular weight:459.99Jaceosidin
CAS:<p>Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.</p>Formula:C17H14O7Purity:98.23% - 99.28%Color and Shape:SolidMolecular weight:330.29Dexketoprofen trometamol
CAS:<p>Dexketoprofen trometamol is a modified non-selective COX inhibitor with a rapid onset of action that is available as both oral and parenteral formulations.</p>Formula:C20H25NO6Purity:99.97% - 99.98%Color and Shape:SolidMolecular weight:375.42Hamaudol
CAS:<p>Hamaudol, from Saposhnikovia divaricata, has pain-relief and anti-inflammatory effects, inhibits COX-1/COX-2 (0.30/0.57 mM).</p>Formula:C15H16O5Purity:99.62%Color and Shape:SolidMolecular weight:276.28Indomethacin heptyl ester
CAS:<p>Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2</p>Formula:C26H30ClNO4Purity:99.86%Color and Shape:SolidMolecular weight:455.97Harpagoside
CAS:<p>Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.</p>Formula:C24H30O11Purity:99.71% - ≥95%Color and Shape:White To Off-White PowderMolecular weight:494.49Suprofen
CAS:<p>Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic.</p>Formula:C14H12O3SPurity:99.23% - 99.33%Color and Shape:SolidMolecular weight:260.31Chlorthenoxazine
CAS:<p>Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.</p>Formula:C10H10ClNO2Purity:99.64%Color and Shape:SolidMolecular weight:211.6420(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.01Ginsenoside C-K
CAS:<p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>Formula:C36H62O8Purity:99.65% - 99.97%Color and Shape:SolidMolecular weight:622.87NB-598 Maleate
CAS:<p>NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.</p>Formula:C31H35NO5S2Purity:98%Color and Shape:SolidMolecular weight:565.74Haloperidol decanoate
CAS:<p>Haloperidol decanoate (KD 16), an antipsychotic, treats schizophrenia and mood disorders as an intramuscular ester.</p>Formula:C31H41ClFNO3Purity:99.57% - 99.72%Color and Shape:SolidMolecular weight:530.11syringaldehyde
CAS:<p>Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species, moderately inhibiting COX-2 activity.</p>Formula:C9H10O4Purity:99.24%Color and Shape:Light Yellow-Green To Brown Crystalline PowderMolecular weight:182.17Ibuprofen Piconol
CAS:<p>Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.</p>Formula:C19H23NO2Purity:99.21%Color and Shape:SolidMolecular weight:297.39EIPA
CAS:<p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>Formula:C11H18ClN7OPurity:96.62% - 99.981%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76Crocin II
CAS:<p>Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.</p>Formula:C38H54O19Purity:98% - 99.00%Color and Shape:SolidMolecular weight:814.82β-Elemonic Acid
CAS:<p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>Formula:C30H46O3Purity:99.61% - 99.8%Color and Shape:SolidMolecular weight:454.68Tryptanthrin
CAS:<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Polmacoxib
CAS:<p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>Formula:C18H16FNO4SPurity:97.88%Color and Shape:SolidMolecular weight:361.39
