Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase(63 products)
- Hedgehog/Smoothened(46 products)
- Hippo pathway(6 products)
- JAK(244 products)
- Porcupine(9 products)
- ROCK(68 products)
- STAT(97 products)
- Stem Cells(477 products)
- TGF-beta/Smad(59 products)
- Wnt/beta-catenin(63 products)
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Found 690 products of "Stem Cell and Derivatives"
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INCB16562
CAS:<p>INCB16562: oral JAK1/2 inhibitor, halts IL-6/STAT3 in myeloma cells, boosts drug efficacy, stunts myeloma in mice.</p>Formula:C19H11Cl2N5Color and Shape:SolidMolecular weight:380.23JAK3-IN-9
CAS:JAK3-IN-9, potent JAK3 inhibitor, IC50 of 1.7 nM, highly selective, low toxicity, orally bioavailable, shows anti-arthritis activity.Formula:C17H23N5O4SColor and Shape:SolidMolecular weight:393.46RR-11a analog
CAS:<p>RR-11a (aza-peptide) inhibits asparaginyl endopeptidase: IC50 - 4.5 nM (T. Vaginalis, I. ricinus), 31 nM (S. mansoni).</p>Formula:C22H29N5O8Purity:98.80%Color and Shape:SolidMolecular weight:491.49TGFβRI-IN-1
CAS:TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII,Formula:C20H14D3N5O2Purity:98%Color and Shape:SolidMolecular weight:362.4JAK-IN-20
CAS:<p>JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.</p>Formula:C28H30FN7O2Color and Shape:SolidMolecular weight:515.58Aβ42-IN-1 free base
CAS:Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091Formula:C29H26N4O2Purity:98%Color and Shape:SolidMolecular weight:462.54JAK-2/3-IN-2
CAS:JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).Formula:C19H19ClN2OSColor and Shape:SolidMolecular weight:358.89Peficitinib hydrochloride
CAS:<p>Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).</p>Formula:C18H23ClN4O2Color and Shape:SolidMolecular weight:362.86BPN-15606
CAS:BPN-15606, an oral γ-secretase modulator, reduces Aβ42/Aβ40 with IC50 of 7/17 nM; promising PK/PD, lowers Aβ in rodent CNS.Formula:C23H23FN6OColor and Shape:SolidMolecular weight:418.47RR-11a
CAS:<p>RR-11a is a synthetic enzyme Legumain inhibitor.</p>Formula:C24H28N6O10Purity:98%Color and Shape:SolidMolecular weight:560.51TK4b
CAS:<p>TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).</p>Formula:C21H22N2O2Color and Shape:SolidMolecular weight:334.41TUL01101
CAS:<p>TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.</p>Formula:C22H25F2N5O2Color and Shape:SolidMolecular weight:429.46γ-Secretase modulator 11
CAS:5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency andFormula:C28H22F2N4O2Color and Shape:SolidMolecular weight:484.5CP-690550A
CAS:Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.Formula:C15H21N5O2Color and Shape:SolidMolecular weight:303.36GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formula:C21H18ClF2N7O3Color and Shape:SolidMolecular weight:489.86Povorcitinib
CAS:Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).Formula:C23H22F5N7OColor and Shape:SolidMolecular weight:507.469(2R,5S)-Ritlecitinib
CAS:(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].Formula:C15H19N5OColor and Shape:SolidMolecular weight:285.34TYK2-IN-11
CAS:TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.Formula:C18H17N5O3SColor and Shape:SolidMolecular weight:383.42JI051
CAS:JI051 has anti-tumor effects and can interact with PHB2 to inhibit the proliferation of HEK293 cells and pancreatic cancer cells.Formula:C22H24N2O3Purity:≥98% - ≥98.0%Color and Shape:SolidMolecular weight:364.44Yhhu-3792
CAS:Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.Formula:C24H24N4O2Color and Shape:SolidMolecular weight:400.47
