CymitQuimica logo
Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

Show 13 more subcategories

Found 1372 products of "Tyrosine Kinase/Adaptors"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Calcineurin substrate
    Targetmol
    + Info

    Calcineurin substrate

    CAS:
    <p>Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase.</p>
    Formula:C92H150N28O29
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2112.35

    Ref: TM-TP1485

  • CymitQuimica logo
    Targetmol
    + Info

    Necitumumab

    CAS:
    <p>Necitumumab (IMC-11F8) is a human monoclonal antibody against EGFR, an anti-angiogenic agent used in the treatment of advanced non-small cell lung cancer.</p>
    Purity:97.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 99.1% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:145.5 kDa

    Ref: TM-T77459

  • EGFR-IN-15
    Targetmol
    + Info

    EGFR-IN-15

    CAS:
    <p>EGFR-IN-15 (compound I-005) is a potent EGFR inhibitor, exhibiting an IC50 value of 4 nM. This compound holds potential for oncological research applications.</p>
    Formula:C24H25BrN6O2
    Color and Shape:Solid
    Molecular weight:509.408

    Ref: TM-T40209

  • CymitQuimica logo
    Targetmol
    + Info

    EGFR-IN-127

    <p>EGFR-IN-127 is an ATP-competitive inhibitor targeting EGFR, with IC50 values of 136.3 nM for EGFRdel19 and 161.2 nM for EGFRdel19/T790M/C797S. This compound holds potential for the study of non-small cell lung cancer (NSCLC).</p>
    Color and Shape:Odour Solid

    Ref: TM-T200430

  • CymitQuimica logo
    Targetmol
    + Info

    EGFR-IN-124

    <p>EGFR-IN-124 (compound 10A) is an EGFR inhibitor with an IC50 value of 0.54 μM, utilized in cancer research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200720

  • SJF 1521
    Targetmol
    + Info

    SJF 1521

    CAS:
    <p>SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.</p>
    Formula:C57H61ClFN7O9S
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:1074.65

    Ref: TM-T36244

  • CymitQuimica logo
    Targetmol
    + Info

    Mecbotamab vedotin

    CAS:
    <p>Mecbotamab vedotin (BA301) is an inhibitory IgG1 antibody that targets human tyrosine kinase receptor AXL and the humanized murine monoclonal BA301 γ1 chain. It can be utilized in the preparation of immunoconjugates for research into cancers expressing the Axl type.</p>
    Color and Shape:Liquid

    Ref: TM-T9901A-225

  • CymitQuimica logo
    Targetmol
    + Info

    DSPE-PEG2000-GE11

    <p>DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.</p>
    Color and Shape:Odour Solid

    Ref: TM-TCL-01177

  • KN1022
    Targetmol
    + Info

    KN1022

    CAS:
    <p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>
    Formula:C21H22N6O5
    Purity:99.68%
    Color and Shape:Soild
    Molecular weight:438.44

    Ref: TM-T60110

  • CymitQuimica logo
    Targetmol
    + Info

    Cetuximab MMAE

    <p>Cetuximab-MMAE, an antibody-drug conjugate (ADC), combines an EGFR-targeting antibody with Monomethyl auristatin E (MMAE) to investigate colorectal and head and neck cancers.</p>
    Color and Shape:Liquid
    Molecular weight:150 kDa

    Ref: TM-T9901A-219

  • CymitQuimica logo
    Targetmol
    + Info

    Antiproliferative agent-57

    <p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200522

  • Motesanib Diphosphate
    Targetmol
    + Info

    Motesanib Diphosphate

    CAS:
    <p>Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic</p>
    Formula:C22H23N5O·2H3PO4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:569.44

    Ref: TM-T2288L

  • Cevidoplenib dimesylate
    Targetmol
    + Info

    Cevidoplenib dimesylate

    CAS:
    <p>Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.</p>
    Formula:C27H35N7O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:665.74

    Ref: TM-T39437

  • KYL peptide
    Targetmol
    + Info

    KYL peptide

    CAS:
    <p>EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines &amp; LTP; long half-life (8-12h), neuroprotective.</p>
    Formula:C74H108N14O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1465.75

    Ref: TM-TP1895

  • CymitQuimica logo
    Targetmol
    + Info

    EGFR-IN-43

    <p>EGFR-IN-43 (17c) is a potent EGFR inhibitor with ER antagonist action, tamoxifen/endoxifen+gefitinib linkage, and strong anticancer activity.</p>
    Formula:C50H55ClFN5O5
    Color and Shape:Solid
    Molecular weight:860.45

    Ref: TM-T74458

  • HER2-IN-13
    Targetmol
    + Info

    HER2-IN-13

    CAS:
    <p>HER2-IN-13 (Compound 33) serves as an effective HER2 inhibitor, exhibiting an IC50 value of 8 nM, and additionally demonstrates inhibition of wt-EGFR with an</p>
    Formula:C26H23ClF2N8O3
    Color and Shape:Solid
    Molecular weight:568.96

    Ref: TM-T75164

  • CymitQuimica logo
    Targetmol
    + Info

    JBJ-09-063 TFA

    <p>JBJ-09-063 TFA, an EGFR inhibitor selective for EGFR mutations, IC50s: 0.147-0.396 nM, blocks EGFR/Akt/ERK signaling, for EGFR-mutant lung cancer research.</p>
    Formula:C33H30F4N4O5S
    Color and Shape:Solid
    Molecular weight:670.67

    Ref: TM-T74561

  • Leucettine L41
    Targetmol
    + Info

    Leucettine L41

    CAS:
    <p>Leucettine L41 (LeucettineL41) is an inhibitor of DYRKs/CLKs, preferentially targeting DYRK1A, and inhibits DYRK2.</p>
    Formula:C17H13N3O3
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:307.3

    Ref: TM-T24402

  • Arginyl-Glutamine
    Targetmol
    + Info

    Arginyl-Glutamine

    CAS:
    <p>Arginyl-Glutamine (Arg-Gln) is a dipeptide nutritional supplement that protects neonatal mice from hyperoxia-induced lung injury, lowering VEGF levels.</p>
    Formula:C11H22N6O4
    Purity:95.2%
    Color and Shape:Solid
    Molecular weight:302.33

    Ref: TM-T76574

  • LDN-193189 2HCl
    Targetmol
    + Info

    LDN-193189 2HCl

    CAS:
    <p>LDN-193189 2HCl inhibits BMP signaling (ALK1/2/3/6), IC50: 0.8-16.7 nM; selective over TGF-β by 200-fold in C2C12 cells.</p>
    Formula:C25H24Cl2N6
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:479.4

    Ref: TM-T35348