Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(135 products)
- CSF-1R(42 products)
- EGFR(551 products)
- Ephrin Receptor(25 products)
- FLT(88 products)
- Fibroblast Growth Factor Receptor (FGFR)(176 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(97 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(53 products)
- Tyrosine Kinases(13 products)
- VEGFR(236 products)
- c-Fms(100 products)
- c-Kit(113 products)
- c-Met/HGFR(138 products)
- c-RET(60 products)
Show 13 more subcategories
Found 1016 products of "Tyrosine Kinase/Adaptors"
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Vandetanib
CAS:Formula:C22H24BrFN4O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:475.36Saracatinib
CAS:Formula:C27H32ClN5O5Purity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:542.03Mavelertinib
CAS:Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Formula:C18H22FN9O2Purity:99.89%Color and Shape:SolidMolecular weight:415.42PF-04217903 methanesulfonate
CAS:PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).Formula:C20H20N8O4SPurity:98%Color and Shape:SolidMolecular weight:468.49Pazopanib Hydrochloride
CAS:Formula:C21H23N7O2S·HClPurity:>95.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:473.98Neratinib maleate
CAS:Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Formula:C34H33ClN6O7Purity:99.99%Color and Shape:SolidMolecular weight:673.11Erlotinib-d6
CAS:Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .Formula:C22H23N3O4Purity:98%Color and Shape:SolidMolecular weight:399.47WHI-P180 Hydrochloride
CAS:Formula:C16H15N3O3·HClPurity:>97.0%(T)(HPLC)Color and Shape:White to Light gray to Light yellow powder to crystalMolecular weight:333.77AV-412 free base
CAS:AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Formula:C27H28ClFN6OColor and Shape:SolidMolecular weight:507(3S,4S)-PF-06459988
CAS:(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formula:C19H22ClN7O3Color and Shape:SolidMolecular weight:431.88PF-06737007
CAS:PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).Formula:C25H28F4N2O6Purity:98%Color and Shape:SolidMolecular weight:528.49Hypericin
CAS:Formula:C30H16O8Purity:>95.0%(HPLC)Color and Shape:Black powder to crystalMolecular weight:504.45Osimertinib dimesylate
CAS:Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Formula:C30H41N7O8S2Purity:98%Color and Shape:SolidMolecular weight:691.82PLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formula:C21H17F3N4Purity:99.38%Color and Shape:SolidMolecular weight:382.38Ref: TM-T1925
2mg39.00€5mg57.00€10mg86.00€25mg127.00€50mg178.00€100mg264.00€200mg389.00€1mL*10mM (DMSO)60.00€BAY-826
CAS:BAY-826 is a novel, potent and selective TIE-2 inhibitor that inhibits TIE-2 phosphorylation and can be used to study tumors.Formula:C26H19F5N6OSPurity:98% - 99.28%Color and Shape:SolidMolecular weight:558.53Cediranib Maleate
CAS:Formula:C25H27FN4O3·C4H4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:566.59A-770041
CAS:A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Formula:C34H39N9O3Purity:99.23% - 99.86%Color and Shape:SolidMolecular weight:621.73Ref: TM-T14074
2mg70.00€5mg104.00€10mg170.00€25mg384.00€50mg652.00€100mg1,018.00€200mg1,350.00€1mL*10mM (DMSO)142.00€BI-4142
CAS:BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.Formula:C28H27N9O2Purity:97.21% - 98.09%Color and Shape:SolidMolecular weight:521.57Ref: TM-T63643
1mg57.00€5mg120.00€10mg177.00€25mg356.00€50mg537.00€100mg803.00€200mg1,341.00€1mL*10mM (DMSO)138.00€HNMPA-(AM)3
CAS:HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。Formula:C20H23O10PPurity:97.22%Color and Shape:SolidMolecular weight:454.36Nilotinib
CAS:Formula:C28H22F3N7OPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:529.53
