FLT
FLT (Fms-like tyrosine kinase) inhibitors are compounds that target FLT receptors, which are involved in the regulation of angiogenesis through the VEGF (vascular endothelial growth factor) pathway. FLT receptors play a crucial role in the development of new blood vessels in tumors. Inhibiting FLT receptors can effectively reduce angiogenesis and tumor growth, making these inhibitors important in cancer therapy. At CymitQuimica, we offer a selection of high-quality FLT inhibitors to support your research in oncology, vascular biology, and angiogenesis.
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FLT3-IN-3
CAS:2229050-90-0
FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y …
Formula:
C27H38N8O
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
490.64
Ref: TM-T11298
| 1mg | 105.00 € | ||
| 5mg | 254.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 700.00 € | ||
| 50mg | 991.00 € | ||
| 100mg | 1,328.00 € | ||
| 500mg | 2,656.00 € | ||
| 1mL*10mM (DMSO) | 276.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
JAK3-IN-14
CAS:454234-24-3
JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, …
Formula:
C18H13N3O
Purity:
98.98%
Color and Shape:
Soild
Molecular weight:
287.32
Ref: TM-T67754
| 1mg | 210.00 € | ||
| 5mg | 609.00 € | ||
| 10mg | 884.00 € | ||
| 25mg | 1,291.00 € | ||
| 50mg | 1,746.00 € | ||
| 100mg | 2,378.00 € | ||
| 1mL*10mM (DMSO) | 536.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
FLT3-IN-10
CAS:2088735-51-5
FLT3-IN-10, a potent FLT3 inhibitor, may treat FLT3-mutated AML.
Formula:
C15H11FN2O
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
254.26
Ref: TM-T9856
| 1mg | 37.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 525.00 € | ||
| 200mg | 713.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
AKN-028
CAS:1175017-90-9
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = …
Formula:
C17H14N6
Purity:
97.3%
Color and Shape:
Solid
Molecular weight:
302.33
Ref: TM-T38562
| 5mg | 57.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 400.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
JI6
CAS:856436-16-3
JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.
Formula:
C19H17N3O4S
Purity:
97.74%
Color and Shape:
Soild
Molecular weight:
383.42
Ref: TM-T64370
| 1mg | 158.00 € | ||
| 5mg | 352.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 848.00 € | ||
| 50mg | 1,143.00 € | ||
| 100mg | 1,561.00 € | ||
| 500mg | 3,139.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
3-Hydroxy Midostaurin
CAS:179237-49-1
3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 …
Formula:
C35H30N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
586.648
Ref: TM-T12610L
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with …
Color and Shape:
Liquid
Molecular weight:
85.45 kDa (predicted); 113.32 kDa (reducing conditions)
Ref: TM-TMPY-06780
| 20µg | 591.00 € | ||
| 100µg | 1,368.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with …
Color and Shape:
Solid
Molecular weight:
85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00451
| 1mg | 5,163.00 € | ||
| 100µg | 798.00 € | ||
| 500µg | 3,085.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi …
Color and Shape:
Liquid
Molecular weight:
85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00450
| 1mg | 2,669.00 € | ||
| 100µg | 420.00 € | ||
| 500µg | 1,592.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FLT1 Protein, Human, Recombinant (aa 1-756, His)
FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His …
Color and Shape:
Solid
Molecular weight:
83.7 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-02108
| 1mg | 2,917.00 € | ||
| 100µg | 491.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FLT1 Protein, Human, Recombinant (hFc)
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Color and Shape:
Solid
Molecular weight:
61.1 kDa (predicted)
Ref: TM-TMPY-00119
| 50µg | 399.00 € | ||
| 500µg | 2,452.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His …
Purity:
97.5%
Color and Shape:
Solid
Molecular weight:
35.6 kDa (predicted)
Ref: TM-TMPY-00637
| 100µg | 387.00 € | ||
| 200µg | 647.00 € | ||
| 500µg | 1,314.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BPR1K871
CAS:2443767-35-7
BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor …
Formula:
C25H28ClN7O2S
Color and Shape:
Solid
Molecular weight:
526.05
Ref: TM-T10592
| 10mg | 1,161.00 € | ||
| 25mg | 1,994.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SB1317
CAS:1204918-72-8
SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), …
Formula:
C23H24N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.46
Ref: TM-T2653
| 2mg | 69.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 122.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 503.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
7BIO
CAS:916440-85-2
7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:
C16H10BrN3O2
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
356.17
Ref: TM-T22012
| 5mg | 44.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 387.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB1317 hydrochloride (1204918-72-8(free base))
SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).
Formula:
C23H25ClN4O
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
408.92
Ref: TM-T4227
| 1mg | 49.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 319.00 € | ||
| 50mg | 388.00 € | ||
| 100mg | 577.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM …
Formula:
C28H42Cl2N6O
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
549.62
Ref: TM-T4419
| 1mg | 55.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 793.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Crenolanib
CAS:670220-88-9
Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and …
Formula:
C26H29N5O2
Purity:
97.45% - 99.28%
Color and Shape:
Solid
Molecular weight:
443.54
Ref: TM-T2677
| 2mg | 57.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 263.00 € | ||
| 100mg | 434.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TCS 359
CAS:301305-73-7
TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.
Formula:
C18H20N2O4S
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
360.43
Ref: TM-T6138
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 152.00 € | ||
| 100mg | 191.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNC2025
CAS:1429881-91-3
UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual …
Formula:
C28H40N6O
Purity:
97.48% - 99.74%
Color and Shape:
Solid
Molecular weight:
476.66
Ref: TM-T7007
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
