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FLT

FLT

FLT (Fms-like tyrosine kinase) inhibitors are compounds that target FLT receptors, which are involved in the regulation of angiogenesis through the VEGF (vascular endothelial growth factor) pathway. FLT receptors play a crucial role in the development of new blood vessels in tumors. Inhibiting FLT receptors can effectively reduce angiogenesis and tumor growth, making these inhibitors important in cancer therapy. At CymitQuimica, we offer a selection of high-quality FLT inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 92 products of "FLT"

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  • PDGFRα/FLT3-ITD-IN-1
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    PDGFRα/FLT3-ITD-IN-1

    CAS:
    <p>PDGFRα/FLT3-ITD-IN-1 are potent inhibitors of PDGFRα/FLT3, and their IC50 values are greater than 0.036 and 0.003 μM, respectively.</p>
    Formula:C27H39N9O
    Color and Shape:Solid
    Molecular weight:505.66

    Ref: TM-T63454

  • BSc5371
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    BSc5371

    CAS:
    <p>BSc5371: Irreversible FLT3 inhibitor; Kds 0.83-5.8 nM for various FLT3 mutants including wild type.</p>
    Formula:C24H31N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.6

    Ref: TM-T10622

  • PDGFRα/FLT3-ITD-IN-3
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    PDGFRα/FLT3-ITD-IN-3

    CAS:
    <p>PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/FLT3-ITD-IN-3 has the potential to be</p>
    Formula:C26H39N9
    Color and Shape:Solid
    Molecular weight:477.65

    Ref: TM-T63127

  • FLT3-IN-11
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    FLT3-IN-11

    CAS:
    <p>FLT3-IN-11, an oral FLT3 kinase inhibitor: potent, selective, IC50 - wild-type 7.22 nM, FLT3-D835Y 4.95 nM, anti-AML IC50 3.2 nM for MV4-11.</p>
    Formula:C20H25F3N6O
    Color and Shape:Solid
    Molecular weight:422.45

    Ref: TM-T62260

  • HP1328
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    HP1328

    CAS:
    <p>HP1328: potent FLT3/ITD inhibitor, reduces leukemia, extends survival in mice, belongs to benzoimidazole family.</p>
    Formula:C23H23N3O3
    Color and Shape:Solid
    Molecular weight:389.45

    Ref: TM-T61758

  • FLT3/ITD-IN-2
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    FLT3/ITD-IN-2

    CAS:
    <p>FLT3/ITD-IN-2: Powerful FLT3/ITD, FLT3D835Y, and FLT3 inhibitor; hinders AML cell growth. IC50s: 0.3-1.0 nM.</p>
    Formula:C23H26F3N7O2
    Color and Shape:Solid
    Molecular weight:489.49

    Ref: TM-T63274

  • KRN383
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    KRN383

    CAS:
    <p>KRN383 inhibits ITD cell growth at ≤2.9 nM, erases ITD tumors in mice at 80 mg/kg dose, and may suit various treatment plans.</p>
    Formula:C17H17N3O4
    Color and Shape:Solid
    Molecular weight:327.33

    Ref: TM-T68346

  • Gilteritinib hemifumarate
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    Gilteritinib hemifumarate

    CAS:
    <p>Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of</p>
    Formula:C29H44N8O3C4H4O4
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:610.75

    Ref: TM-T71973

  • AXL-IN-13
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    AXL-IN-13

    CAS:
    <p>AXL-IN-13: potent, oral AXL inhibitor, IC50=1.6nM, Kd=0.26nM, anti-cancer, inhibits EMT, cell migration &amp; invasion.</p>
    Formula:C34H41FN6O5
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:632.72

    Ref: TM-T73300

  • AC710
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    AC710

    CAS:
    <p>AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).</p>
    Formula:C31H42N6O4
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:562.7

    Ref: TM-TQ0235

  • FLT3-IN-4
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    FLT3-IN-4

    CAS:
    <p>FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenous</p>
    Formula:C23H25N7O2
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:431.49

    Ref: TM-T11299

  • FN-1501
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    FN-1501

    CAS:
    <p>FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).</p>
    Formula:C22H25N9O
    Purity:97.4%
    Color and Shape:Solid
    Molecular weight:431.49

    Ref: TM-T15335

  • AAE871
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    AAE871

    CAS:
    <p>AAE871 is a type I FLT3 inhibitor.</p>
    Formula:C24H34N8O2S
    Color and Shape:Solid
    Molecular weight:498.64

    Ref: TM-T69497

  • LBW242
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    LBW242

    CAS:
    <p>LBW242: oral 3-mer Smac mimetic, IAP inhibitor, targets multiple myeloma, enhances TRAIL/chemo death in ovarian cancer, active on mutant FLT3 cells.</p>
    Formula:C27H42N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.65

    Ref: TM-T15723

  • FLT3/ITD-IN-3
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    FLT3/ITD-IN-3

    CAS:
    <p>FLT3/ITD-IN-3 (Compound 19) is a potent FLT3-ITD inhibitor with IC50 values: FLT3D835Y (0.3 nM), FLT3 (0.4 nM), inhibits AML cell proliferation.</p>
    Formula:C22H26ClN7O2
    Color and Shape:Solid
    Molecular weight:455.94

    Ref: TM-T62824

  • GTP-14564
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    GTP-14564

    CAS:
    <p>GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.</p>
    Formula:C15H10N2O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:234.25

    Ref: TM-T71857

  • TG-89
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    TG-89

    CAS:
    <p>TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and</p>
    Formula:C26H34N6O3S
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:510.65

    Ref: TM-T20742

  • OTS447
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    OTS447

    CAS:
    <p>OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .</p>
    Formula:C27H32ClN3O2
    Purity:98.78%
    Color and Shape:Solid
    Molecular weight:466.02

    Ref: TM-T62979

  • UNC4203
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    UNC4203

    CAS:
    <p>UNC4203 inhibits MERTK (1.2 nM), AXL (140 nM), TYRO3 (42 nM), FLT3 (90 nM); potent, selective, oral.</p>
    Formula:C30H44N6O
    Color and Shape:Solid
    Molecular weight:504.71

    Ref: TM-T63444

  • FLT3/ITD-IN-5
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    FLT3/ITD-IN-5

    CAS:
    <p>FLT3/ITD-IN-5 (Example 6) is an orally active inhibitor of both FLT3 and FLT3-ITD, exhibiting IC50 values of 0.088 nM and 0.348 nM, respectively. This compound is utilized in cancer research.</p>
    Formula:C23H25N7O2
    Color and Shape:Solid
    Molecular weight:431.49

    Ref: TM-T88606