c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
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N-Desmethyl imatinib
CAS:404844-02-6
N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target …
Formula:
C28H29N7O
Purity:
98.60%
Color and Shape:
Off-White To Pale-Yellow Solid
Molecular weight:
479.58
Ref: TM-T11641
| 1mg | 91.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 316.00 € | ||
| 25mg | 534.00 € | ||
| 50mg | 768.00 € | ||
| 100mg | 1,060.00 € | ||
| 1mL*10mM (DMSO) | 177.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Imatinib Mesylate
CAS:220127-57-1
Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, …
Formula:
C29H31N7O·CH4SO3
Purity:
100% - 98.92%
Color and Shape:
White Crystalline Powder
Molecular weight:
589.71
Ref: TM-T1621
| 1u | 163.20 € | ||
| 200mg | 59.00 € | ||
| 500mg | 89.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Lenvatinib
CAS:417716-92-8
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, …
Formula:
C21H19ClN4O4
Purity:
98.46% - 99.8000%
Color and Shape:
Solid
Molecular weight:
426.85
Ref: TM-T0520
| 5mg | 48.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 119.00 € | ||
| 100mg | 175.00 € | ||
| 500mg | 430.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Pazopanib
CAS:444731-52-6
Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor …
Formula:
C21H23N7O2S
Purity:
98.78% - 99.84%
Color and Shape:
White Powder
Molecular weight:
437.52
Ref: TM-T0097L
| 10mg | 50.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 143.00 € | ||
| 200mg | 232.00 € | ||
| 500mg | 326.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Motesanib Diphosphate
CAS:857876-30-3
Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase …
Formula:
C22H23N5O·2H3PO4
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
569.44
Ref: TM-T2288L
| 5mg | 42.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 276.00 € | ||
| 500mg | 677.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
KG5
CAS:877874-85-6
KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM …
Formula:
C20H16F3N7OS
Purity:
98.2%
Color and Shape:
Liquid
Molecular weight:
459.45
Ref: TM-T41003
| 1mg | 34.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 302.00 € | ||
| 100mg | 434.00 € | ||
| 200mg | 608.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
M4205
CAS:2590556-80-0
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, …
Formula:
C29H32N8O
Purity:
98.52%
Color and Shape:
Liquid
Molecular weight:
508.62
Ref: TM-T9689
| 1mg | 52.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 588.00 € | ||
| 200mg | 792.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
c-Kit Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Purity:
98.2%
Color and Shape:
Liquid
Molecular weight:
57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01802
| 100µg | 358.00 € | ||
| 200µg | 633.00 € | ||
| 500µg | 1,336.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including …
Color and Shape:
Liquid
Molecular weight:
56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-01270
| 1mg | 3,005.00 € | ||
| 100µg | 451.00 € | ||
| 500µg | 1,803.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PLX647
CAS:873786-09-5
PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
Formula:
C21H17F3N4
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
382.38
Ref: TM-T1925
| 2mg | 44.00 € | ||
| 5mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells …
Color and Shape:
Liquid
Molecular weight:
76.8 kDa (predicted); 68 kDa (reducing conditions)
Ref: TM-TMPY-04564
| 50µg | 368.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with …
Color and Shape:
Liquid
Molecular weight:
58.50 kDa (predicted); 87.1 kDa (reducing conditions)
Ref: TM-TMPY-06656
| 20µg | 557.00 € | ||
| 100µg | 1,290.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01935
| 100µg | 357.00 € | ||
| 200µg | 631.00 € | ||
| 500µg | 1,332.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Color and Shape:
Liquid
Molecular weight:
82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01801
| 100µg | 557.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.
Color and Shape:
Solid
Molecular weight:
17.9 kDa (predicted); 18 kDa (reducing conditions)
Ref: TM-TMPY-03567
| 100µg | 650.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD117 Protein, Mouse, Recombinant (His)
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types …
Color and Shape:
Liquid
Molecular weight:
56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00777
| 1mg | 3,014.00 € | ||
| 100µg | 452.00 € | ||
| 500µg | 1,809.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Purity:
97.1%
Color and Shape:
Liquid
Molecular weight:
82 kDa (predicted); 93-115 kDa (reducing conditions)
Ref: TM-TMPY-04051
| 50µg | 237.00 € | ||
| 100µg | 404.00 € | ||
| 200µg | 688.00 € | ||
| 500µg | 1,382.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types …
Color and Shape:
Solid
Molecular weight:
58.60 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00805
| 1mg | 5,045.00 € | ||
| 100µg | 755.00 € | ||
| 500µg | 3,014.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Toceranib
CAS:356068-94-5
Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM …
Formula:
C22H25FN4O2
Purity:
97.14%
Color and Shape:
Solid
Molecular weight:
396.46
Ref: TM-T13178
| 10mg | 46.00 € | ||
| 25mg | 64.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 114.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD3229
CAS:2248003-60-1
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.
Formula:
C24H26FN7O3
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
479.51
Ref: TM-T5409
| 1mg | 43.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 491.00 € | ||
| 200mg | 674.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
