c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
Found 117 products of "c-Kit"
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Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Formula:C29H31N7O·CH4SO3Purity:98% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:589.71Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formula:C21H19ClN4O4Purity:98.46% - 99.96%Color and Shape:SolidMolecular weight:426.85Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formula:C22H18N4OSPurity:98.9% - 99.74%Color and Shape:Off-White SolidMolecular weight:386.47N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.58Ref: TM-T11641
1mg87.00€5mg166.00€10mg303.00€25mg512.00€50mg737.00€100mg1,018.00€1mL*10mM (DMSO)170.00€Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurity:98.78% - 99.85%Color and Shape:White PowderMolecular weight:437.52Ref: TM-T0097L
10mg47.00€25mg70.00€50mg90.00€100mg138.00€200mg225.00€500mg314.00€1mL*10mM (DMSO)56.00€JI6
CAS:JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.Formula:C19H17N3O4SPurity:98.51%Color and Shape:SoildMolecular weight:383.42Eglatoprutug
CAS:Eglatoprutug is a humanized immunoglobulin G1-kappa monoclonal antibody targeting the c-Kit receptor [1].Color and Shape:LiquidKG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).
Formula:C20H16F3N7OSPurity:98.32%Color and Shape:SolidMolecular weight:459.45c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.Formula:C25H28FN5O5Color and Shape:SolidMolecular weight:497.52M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formula:C29H32N8OPurity:99.07%Color and Shape:SolidMolecular weight:508.62Ref: TM-T9689
1mg50.00€5mg110.00€10mg170.00€25mg290.00€50mg414.00€100mg572.00€200mg772.00€1mL*10mM (DMSO)122.00€Amuvatinib hydrochloride
CAS:Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.Formula:C23H22ClN5O3SPurity:98%Color and Shape:SolidMolecular weight:483.97Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormula:C22H23N5O·2H3PO4Purity:99.69%Color and Shape:SolidMolecular weight:569.44Multi-kinase-IN-5
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,Formula:C19H15N5O2SColor and Shape:SolidMolecular weight:377.42Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Color and Shape:Odour LiquidAnti-C-Kit Antibody (9Y519)
Anti-C-Kit Antibody (9Y519) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (9Y519) can be used in ELISA.Color and Shape:Odour LiquidAnti-C-Kit Antibody-FITC (7P530)
Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.Color and Shape:Odour LiquidN-Desethyl Sunitinib
CAS:N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,Formula:C20H23FN4O2Purity:98%Color and Shape:SolidMolecular weight:370.42SU14813 maleate
CAS:SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formula:C27H31FN4O8Purity:98%Color and Shape:SolidMolecular weight:558.56Anti-CD117 Antibody (9H202)
Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody (8E724)
Anti-C-Kit Antibody (8E724) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (8E724) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody-PE (8E724)
Anti-C-Kit Antibody-PE (8E724) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (8E724) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody (3F840)
Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.Color and Shape:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Color and Shape:Odour LiquidAnti-C-Kit Antibody (1R766)
Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody (7P530)
Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody-PE (7P530)
Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody-APC (1R766)
Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody (3N57)
Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).Color and Shape:Odour Liquidc-Kit/CD117 Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Purity:97.1%Color and Shape:Lyophilized PowderMolecular weight:82 kDa (predicted); 93-115 kDa (reducing conditions)c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Color and Shape:Lyophilized PowderMolecular weight:56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit/CD117 Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)Telatinib mesylate
CAS:Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Formula:C21H20ClN5O6SColor and Shape:SolidMolecular weight:505.93c-Kit/CD117 Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:99.4%Color and Shape:Lyophilized PowderMolecular weight:56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:98.2%Color and Shape:Lyophilized PowderMolecular weight:57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:17.9 kDa (predicted); 18 kDa (reducing conditions)c-Kit/CD117 Protein, Human, Recombinant (aa 540-972, His & GST)
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells with His and GST tag.Color and Shape:Lyophilized PowderMolecular weight:76.8 kDa (predicted); 68 kDa (reducing conditions)PLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formula:C21H17F3N4Purity:99.38%Color and Shape:SolidMolecular weight:382.38Ref: TM-T1925
2mg39.00€5mg57.00€10mg86.00€25mg127.00€50mg178.00€100mg264.00€200mg389.00€1mL*10mM (DMSO)60.00€c-Kit/CD117 Protein, Mouse, Recombinant (His)
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Color and Shape:Lyophilized PowderMolecular weight:56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.Anti-C-Kit Antibody (6X205)
Anti-C-Kit Antibody (6X205) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (6X205) can be used in ELISA.Color and Shape:Odour LiquidAnti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidAnti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Color and Shape:Odour LiquidDovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurity:99.35% - 99.92%Color and Shape:SolidMolecular weight:392.43ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Formula:C19H21N3O2SPurity:98.39%Color and Shape:SolidMolecular weight:355.45JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:SolidMolecular weight:364.79Ref: TM-T22349
1mg38.00€5mg78.00€10mg103.00€25mg172.00€50mg250.00€100mg338.00€200mg464.00€1mL*10mM (DMSO)84.00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45BLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formula:C27H29FN10OPurity:99.01% - 99.67%Color and Shape:SolidMolecular weight:528.58Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07% - 99.62%Color and Shape:SolidMolecular weight:510.36Ref: TM-T8482
1mg74.00€2mg97.00€5mg165.00€10mg274.00€25mg432.00€50mg692.00€100mg1,121.00€200mg1,539.00€1mL*10mM (DMSO)202.00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:98.13%Color and Shape:SolidMolecular weight:442.48Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formula:C26H27FN10Purity:96.59% - 99.7%Color and Shape:SolidMolecular weight:498.56Ref: TM-T5109
1mg38.00€5mg80.00€10mg120.00€25mg235.00€50mg354.00€100mg588.00€200mg833.00€1mL*10mM (DMSO)175.00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formula:C20H17F3N4O3Purity:99.34%Color and Shape:SolidMolecular weight:418.37Ref: TM-T4191
1mg37.00€2mg52.00€5mg79.00€10mg101.00€25mg177.00€50mg268.00€100mg385.00€1mL*10mM (DMSO)87.00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:98.97% - 99.88%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg44.00€5mg90.00€10mg145.00€25mg268.00€50mg439.00€100mg700.00€200mg954.00€1mL*10mM (DMSO)90.00€Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formula:C29H29F3N8OPurity:99.39% - 99.95%Color and Shape:SolidMolecular weight:562.59Ref: TM-T4320
1mg34.00€5mg63.00€10mg82.00€25mg120.00€50mg155.00€100mg259.00€200mg388.00€500mg642.00€1mL*10mM (DMSO)82.00€AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49AZD3229 Tosylate
CAS:AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinalFormula:C31H34FN7O6SColor and Shape:SolidMolecular weight:651.71Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€1mL*10mM (DMSO)90.00€Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg51.00€10mg79.00€25mg129.00€50mg213.00€100mg358.00€200mg535.00€500mg843.00€1mL*10mM (DMSO)57.00€Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purity:99.45% - ≥98%Color and Shape:White SolidMolecular weight:562.7Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formula:C23H25N7O2Purity:99.05% - 99.57%Color and Shape:SolidMolecular weight:431.49Ref: TM-T10652
1mg87.00€5mg178.00€10mg295.00€25mg505.00€50mg690.00€100mg888.00€1mL*10mM (DMSO)203.00€SKLB4771
CAS:SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formula:C25H27N7O3S2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:537.66Ref: TM-T2051
1mg63.00€2mg93.00€5mg124.00€10mg177.00€25mg371.00€50mg557.00€100mg792.00€500mg1,611.00€1mL*10mM (DMSO)148.00€AZD3229
CAS:AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.Formula:C24H26FN7O3Purity:98.83%Color and Shape:SolidMolecular weight:479.51Ref: TM-T5409
1mg44.00€5mg87.00€10mg140.00€25mg248.00€50mg364.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)99.00€c-Kit-IN-1
CAS:c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formula:C26H21F2N5O3Purity:98.72% - 98.73%Color and Shape:SolidMolecular weight:489.47Ref: TM-T4332
1mg39.00€5mg81.00€10mg120.00€25mg235.00€50mg373.00€100mg610.00€200mg840.00€1mL*10mM (DMSO)88.00€Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurity:99.42% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formula:C20H16ClN5O3Purity:97.61% - 99.81%Color and Shape:SolidMolecular weight:409.83Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg48.00€10mg80.00€25mg119.00€50mg178.00€100mg259.00€200mg477.00€500mg772.00€1mL*10mM (DMSO)50.00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98N-Desethylsunitinib hydrochloride
CAS:N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Formula:C20H24ClFN4O2Purity:99.42%Color and Shape:SolidMolecular weight:406.88JNK-IN-8
CAS:JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).Formula:C29H29N7O2Purity:99.24% - >99.99%Color and Shape:SolidMolecular weight:507.59Ref: TM-T2668
2mg47.00€5mg77.00€10mg119.00€25mg207.00€50mg344.00€100mg510.00€200mg722.00€1mL*10mM (DMSO)87.00€CP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormula:C24H27N5O2Purity:99.62% - 99.88%Color and Shape:SolidMolecular weight:417.5Ref: TM-T6091
1mg49.00€2mg63.00€5mg90.00€10mg170.00€25mg334.00€50mg512.00€100mg737.00€500mg1,521.00€1mL*10mM (DMSO)108.00€KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formula:C24H18F3N3O4Purity:99.22% - 99.9%Color and Shape:SolidMolecular weight:469.41Ref: TM-T2446
2mg34.00€5mg50.00€10mg81.00€25mg147.00€50mg279.00€100mg447.00€200mg635.00€1mL*10mM (DMSO)52.00€GNF-5837
CAS:GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).Formula:C28H21F4N5O2Purity:97.26% - 98.08%Color and Shape:SolidMolecular weight:535.49Ref: TM-T6097
5mg48.00€10mg80.00€25mg117.00€50mg178.00€100mg295.00€200mg384.00€500mg622.00€1mL*10mM (DMSO)52.00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Formula:C22H23N5OPurity:98% - 99.09%Color and Shape:SolidMolecular weight:373.45Ref: TM-T2288
5mg34.00€10mg49.00€25mg81.00€50mg114.00€100mg160.00€200mg230.00€500mg389.00€1mL*10mM (DMSO)39.00€Gilteritinib
CAS:Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Formula:C29H44N8O3Purity:97.75% - 99.90%Color and Shape:SolidMolecular weight:552.71Ref: TM-T4409
1g1,288.00€1mg38.00€2mg52.00€5mg85.00€10mg114.00€25mg177.00€50mg261.00€100mg411.00€500mg954.00€Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82Ref: TM-T1792
5mg34.00€10mg49.00€25mg75.00€50mg90.00€100mg137.00€200mg175.00€500mg294.00€1mL*10mM (DMSO)54.00€Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurity:99.03% - 99.79%Color and Shape:SolidMolecular weight:522.96Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:266.29Ref: TM-T6711
2mg40.00€5mg58.00€10mg90.00€25mg180.00€50mg279.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)81.00€Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurity:99.38% - >99.99%Color and Shape:SolidMolecular weight:447.51Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purity:98.34% - 99.45%Color and Shape:SolidMolecular weight:417.81Ref: TM-T2115
5mg46.00€10mg58.00€25mg90.00€50mg114.00€100mg145.00€200mg192.00€500mg333.00€1mL*10mM (DMSO)49.00€Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51Flumatinib mesylate
CAS:Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formula:C30H33F3N8O4SPurity:99.82%Color and Shape:SolidMolecular weight:658.69Ref: TM-T7861
1mg34.00€5mg84.00€10mg126.00€25mg236.00€50mg371.00€100mg595.00€500mg1,234.00€1mL*10mM (DMSO)132.00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Ref: TM-T5164
1mg42.00€2mg52.00€5mg65.00€10mg92.00€25mg160.00€50mg235.00€100mg330.00€200mg538.00€500mg860.00€Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formula:C29H34N6O4S2Purity:97.67% - 98.44%Color and Shape:SolidMolecular weight:594.75Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurity:98.9% - 99.85%Color and Shape:SolidMolecular weight:629.68Ref: TM-T4349
5mg49.00€10mg74.00€25mg130.00€50mg200.00€100mg319.00€200mg507.00€500mg800.00€1mL*10mM (DMSO)69.00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg34.00€2mg49.00€5mg74.00€10mg113.00€25mg177.00€50mg334.00€100mg500.00€500mg1,099.00€1mL*10mM (DMSO)87.00€c-Kit/CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Color and Shape:Lyophilized PowderMolecular weight:58.60 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00805
5µg94.00€10µg138.00€20µg220.00€50µg434.00€100µg732.00€200µg1,324.00€500µg2,925.00€Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formula:C22H25FN4O2Purity:97.62%Color and Shape:SolidMolecular weight:396.46Barzolvolimab
CAS:Barzolvolimab (CDX 0159) is a humanized monoclonal antibody targeting KIT that reduces skin mast cells and disease activity in chronic inducible urticaria.Purity:95% - 95.6% (SDS-PAGE); 95.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.63 kDaBriquilimab
CAS:Briquilimab is a humanized antibody that inhibits the SCF-KIT interaction, inducing mast cell apoptosis for research into inflammatory diseases.Purity:95% - 96.0% (SDS-PAGE); 96.0% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.56 KDaAnti-Mouse CD117 Antibody
Anti-Mouse CD117 Antibody, a rat-derived IgG2b isotype, acts as an inhibitor specific to the mouse CD117 antigen.Purity:98%Color and Shape:Odour LiquidDovitinib Dilactic Acid
CAS:Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.Formula:C21H21FN6O·2C3H6O3Purity:98%Color and Shape:SolidMolecular weight:572.59KBP-7018 HCl
CAS:KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).Formula:C31H31ClN4O5Color and Shape:SolidMolecular weight:575.06c-Kit-IN-3
CAS:c-Kit-IN-3 is a selective inhibitor of c-KIT kinase with IC50s of 4 nM and 8 nM for c-Kit (wt) and c-Kit (T670I).Formula:C26H20ClF3N2O4Purity:99.94%Color and Shape:SolidMolecular weight:516.9Ref: TM-T10651
1mg87.00€5mg162.00€10mg254.00€25mg419.00€50mg562.00€100mg787.00€500mg1,578.00€1mL*10mM (DMSO)334.00€GW694590A
CAS:GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].Formula:C22H19N5O4Color and Shape:SolidMolecular weight:417.42Sitravatinib malate
CAS:Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5
Formula:C37H35F2N5O9SPurity:98%Color and Shape:SolidMolecular weight:763.76Bezuclastinib
CAS:Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.Formula:C19H17N5OPurity:99.55%Color and Shape:SolidMolecular weight:331.37KI-328
CAS:KI-328: novel selective KIT kinase inhibitor; blocks Wt/mutant-KIT cell growth; low effect on D816V-KIT.Formula:C25H25N7O3Color and Shape:SolidMolecular weight:471.51
