IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Read more
AGL-2263
CAS:638213-98-6
AGL-2263 is a blocker of insulin receptor (IR)
Formula:
C17H10N2O5
Color and Shape:
Solid
Molecular weight:
322.27
Ref: TM-T14142
| 1mg | 70.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Monday 7 Apr 2025
ALK inhibitor 1
CAS:761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
Formula:
C23H28BrN7O3S
Purity:
98.27%
Color and Shape:
Solid
Molecular weight:
562.48
Ref: TM-T10285
| 1mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 143.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
AZ7550 hydrochloride
CAS:2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R …
Formula:
C27H32ClN7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
522.04
Ref: TM-T13564L
| 1mg | 124.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 378.00 € | ||
| 25mg | 630.00 € | ||
| 50mg | 898.00 € |
Estimated delivery in United States, on Thursday 10 Apr 2025
HNMPA
CAS:132541-52-7
HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.
Formula:
C11H11O4P
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
238.18
Ref: TM-T21761
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 660.00 € | ||
| 500mg | 1,396.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Thursday 10 Apr 2025
WAY-270250
CAS:852367-46-5
WAY-270250 is an IGF-1R/SRC inhibitor.
Formula:
C18H16N2O2
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
292.33
Ref: TM-T77624
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 303.00 € | ||
| 100mg | 449.00 € | ||
| 500mg | 1,014.00 € |
Estimated delivery in United States, on Thursday 10 Apr 2025
AZ7550 trimesylate salt
CAS:2319837-99-3
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 inhibits IGF1R activity …
Formula:
C30H43N7O11S3
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
773.9
Ref: TM-T13564L2
| 1mg | 146.00 € |
Estimated delivery in United States, on Thursday 10 Apr 2025
PQ401
CAS:196868-63-0
PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
Formula:
C18H16ClN3O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
341.79
Ref: TM-T2085
| 5mg | 69.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 449.00 € | ||
| 500mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Thursday 10 Apr 2025
NBI-31772
CAS:374620-70-9
NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki …
Formula:
C17H11NO7
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
341.27
Ref: TM-T8906
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 753.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Thursday 10 Apr 2025
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00456
| 1mg | 5,333.00 € | ||
| 100µg | 824.00 € | ||
| 500µg | 3,185.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00455
| 1mg | 3,185.00 € | ||
| 100µg | 493.00 € | ||
| 500µg | 1,911.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
IGF1R/CD221 Protein, Mouse, Recombinant (His)
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Color and Shape:
Liquid
Molecular weight:
105.2 kDa (predicted); 172.5 kDa, 117.1 kDa and 49.8 kDa, corresponding to the single chain, α subunit and β subunit respectively (reducing condition, due to glycosylation)
Ref: TM-TMPY-06195
| 1mg | 4,479.00 € | ||
| 100µg | 709.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
KW-2450 free base
CAS:904899-25-8
KW-2450 free base is a multiple inhibitor of IGF-1R/IR and tyrosine kinases with antitumor activity.
Formula:
C28H29N5O3S
Purity:
99.11%
Color and Shape:
Liquid
Molecular weight:
515.63
Ref: TM-T68405
| 1mg | 558.00 € | ||
| 2mg | 800.00 € | ||
| 5mg | 1,216.00 € | ||
| 10mg | 1,644.00 € | ||
| 25mg | 2,442.00 € | ||
| 50mg | 3,212.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
GSK1904529A
CAS:1089283-49-7
GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
Formula:
C44H47F2N9O5S
Purity:
98.07% - 99%
Color and Shape:
Solid
Molecular weight:
851.96
Ref: TM-T6003
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 117.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 298.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
80.59 kDa (alpha subunit) and 19.28 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 48-58 kDa (beta subunit) and 100-115 kDa (alpha subunit) and 130-150 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00658
| 1mg | 3,185.00 € | ||
| 100µg | 493.00 € | ||
| 500µg | 1,911.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Indirubin Derivative E804
CAS:854171-35-0
Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with …
Formula:
C20H19N3O4
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T11654
| 1mg | 49.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | 459.00 € | ||
| 200mg | 657.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Ceritinib dihydrochloride
CAS:1380575-43-8
Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase …
Formula:
C28H38Cl3N5O3S
Purity:
99.85% - 99.99%
Color and Shape:
Solid
Molecular weight:
631.06
Ref: TM-T1791L
| 5mg | 50.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 124.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Ceritinib
CAS:1032900-25-6
Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor …
Formula:
C28H36ClN5O3S
Purity:
100% - 99.77%
Color and Shape:
Solid
Molecular weight:
558.14
Ref: TM-T1791
| 5mg | 49.00 € | ||
| 10mg | 69.00 € | ||
| 50mg | 89.00 € | ||
| 100mg | 134.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Picropodophyllin
CAS:477-47-4
Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other …
Formula:
C22H22O8
Purity:
98.88% - 99.55%
Color and Shape:
Solid
Molecular weight:
414.41
Ref: TM-T6943
| 5mg | 64.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 535.00 € | ||
| 500mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
BMS-536924
CAS:468740-43-4
BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest …
Formula:
C25H26ClN5O3
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
479.96
Ref: TM-T6419
| 1mg | 39.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 470.00 € | ||
| 100mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
PQ401 hydrochloride (196868-63-0(free base))
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
Formula:
C18H17Cl2N3O2
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
378.25
Ref: TM-T4324
| 2mg | 35.00 € | ||
| 5mg | 48.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 286.00 € | ||
| 200mg | 418.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
