IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
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AZ7550 hydrochloride
CAS:2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R …
Formula:
C27H32ClN7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
522.04
Ref: TM-T13564L
| 1mg | 124.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 378.00 € | ||
| 25mg | 630.00 € | ||
| 50mg | 898.00 € |
Estimated delivery in United States, on Tuesday 12 Aug 2025
Robatumumab
CAS:934235-44-6
Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative …
Purity:
96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)
Color and Shape:
Liquid
Ref: TM-T76759
| 1mg | 194.00 € | ||
| 5mg | 493.00 € | ||
| 10mg | 777.00 € | ||
| 25mg | 1,164.00 € | ||
| 50mg | 1,569.00 € |
Estimated delivery in United States, on Tuesday 12 Aug 2025
GIP (human) acetate
GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.
Purity:
98.65%
Color and Shape:
Soild
Ref: TM-TP2018L
| 1mg | 226.00 € | ||
| 5mg | 540.00 € | ||
| 10mg | 802.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 2,278.00 € | ||
| 100mg | 3,456.00 € |
Estimated delivery in United States, on Tuesday 12 Aug 2025
GIP (3-42), human
CAS:1802086-25-4
Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes …
Formula:
C214H324N58O63S
Purity:
95.73%
Color and Shape:
Solid
Molecular weight:
4749.35
Ref: TM-T37589
| 1mg | 187.00 € | ||
| 5mg | 462.00 € | ||
| 10mg | 662.00 € | ||
| 25mg | 1,035.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,882.00 € |
Estimated delivery in United States, on Tuesday 12 Aug 2025
ALK inhibitor 1
CAS:761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
Formula:
C23H28BrN7O3S
Purity:
98.27%
Color and Shape:
Solid
Molecular weight:
562.48
Ref: TM-T10285
| 1mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 143.00 € |
Estimated delivery in United States, on Tuesday 12 Aug 2025
Ganitumab
CAS:905703-97-1
Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used …
Purity:
100% (SEC-HPLC) - > 95%
Color and Shape:
Liquid
Molecular weight:
145.70 kDa
Ref: TM-T76810
| 1mg | 274.00 € | ||
| 5mg | 717.00 € | ||
| 10mg | 1,121.00 € | ||
| 25mg | 1,691.00 € | ||
| 50mg | 2,270.00 € |
Estimated delivery in United States, on Tuesday 12 Aug 2025
Teprotumumab
CAS:1036734-93-6
Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.
Purity:
SDS-PAGE:95.2%;SEC-HPLC:99.6%
Color and Shape:
Liquid
Molecular weight:
145.62 kDa
Ref: TM-T76727
| 1mg | 160.00 € | ||
| 5mg | 439.00 € | ||
| 10mg | 705.00 € | ||
| 25mg | 1,064.00 € | ||
| 50mg | 1,415.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
Cixutumumab
CAS:947687-12-9
Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor …
Purity:
98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)
Color and Shape:
Liquid
Ref: TM-T78279
| 1mg | 116.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 502.00 € | ||
| 25mg | 800.00 € | ||
| 50mg | 1,074.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
Insulin efsitora alfa
CAS:2131038-11-2
Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel …
Purity:
98.3% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.3% (SDS-PAGE); 98.1% (SEC-HPLC)
Color and Shape:
Liquid
Ref: TM-T77037
| 1mg | 406.00 € | ||
| 5mg | 1,064.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
HNMPA
CAS:132541-52-7
HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.
Formula:
C11H11O4P
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
238.18
Ref: TM-T21761
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 660.00 € | ||
| 500mg | 1,396.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
PQ401
CAS:196868-63-0
PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
Formula:
C18H16ClN3O2
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
341.79
Ref: TM-T2085
| 2mg | 44.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 429.00 € | ||
| 200mg | 620.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
WAY-270250
CAS:852367-46-5
WAY-270250 is an IGF-1R/SRC inhibitor.
Formula:
C18H16N2O2
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
292.33
Ref: TM-T77624
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 269.00 € | ||
| 200mg | 378.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
NBI-31772
CAS:374620-70-9
NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki …
Formula:
C17H11NO7
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
341.27
Ref: TM-T8906
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 753.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
cis-NVP-ADW742
CAS:475489-15-7
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R …
Formula:
C28H31N5O
Color and Shape:
Solid
Molecular weight:
453.59
Ref: TM-T2107
| 1mg | 35.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
AZ7550 trimesylate salt
CAS:2319837-99-3
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 inhibits IGF1R activity …
Formula:
C30H43N7O11S3
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
773.9
Ref: TM-T13564L2
| 1mg | 146.00 € |
Estimated delivery in United States, on Wednesday 13 Aug 2025
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Lyophilized Powder
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00455
| 100µg | 493.00 € | ||
| 500µg | 1,911.00 € |
Estimated delivery in United States, on Monday 18 Aug 2025
GSK1904529A
CAS:1089283-49-7
GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
Formula:
C44H47F2N9O5S
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
851.96
Ref: TM-T6003
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 117.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 298.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Monday 18 Aug 2025
Indirubin Derivative E804
CAS:854171-35-0
Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with …
Formula:
C20H19N3O4
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T11654
| 1mg | 44.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | 459.00 € | ||
| 200mg | 657.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Monday 18 Aug 2025
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Lyophilized Powder
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00456
| 100µg | 824.00 € | ||
| 500µg | 3,185.00 € |
Estimated delivery in United States, on Monday 18 Aug 2025
IGF1R/CD221 Protein, Mouse, Recombinant (His)
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Color and Shape:
Lyophilized Powder
Molecular weight:
80.72+23.0 kDa (predicted); 110-140 kDa and 50-65 kDa, corresponding to the α subunit and β subunit respectively (reducing condition, due to glycosylation)
Ref: TM-TMPY-06195
| 1mg | 4,479.00 € | ||
| 100µg | 709.00 € |
Estimated delivery in United States, on Monday 18 Aug 2025
