IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
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AGL-2263
CAS:638213-98-6
AGL-2263 is a blocker of insulin receptor (IR)
Formula:
C17H10N2O5
Color and Shape:
Solid
Molecular weight:
322.27
Ref: TM-T14142
| 1mg | 70.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
ALK inhibitor 1
CAS:761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
Formula:
C23H28BrN7O3S
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
562.48
Ref: TM-T10285
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 621.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
PQ401
CAS:196868-63-0
PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
Formula:
C18H16ClN3O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
341.79
Ref: TM-T2085
| 5mg | 73.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 444.00 € | ||
| 500mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NBI-31772
CAS:374620-70-9
NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki …
Formula:
C17H11NO7
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
341.27
Ref: TM-T8906
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 154.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 722.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
HNMPA
CAS:132541-52-7
HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.
Formula:
C11H11O4P
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
238.18
Ref: TM-T21761
| 1mg | 51.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 648.00 € | ||
| 500mg | 1,371.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AZ7550 hydrochloride
CAS:2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R …
Formula:
C27H32ClN7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
522.04
Ref: TM-T13564L
| 1mg | 122.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 371.00 € | ||
| 25mg | 619.00 € | ||
| 50mg | 882.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
WAY-270250
CAS:852367-46-5
WAY-270250 is an IGF-1R/SRC inhibitor.
Formula:
C18H16N2O2
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
292.33
Ref: TM-T77624
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | 997.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
KW-2450 free base
CAS:904899-25-8
KW-2450 free base is a multiple inhibitor of IGF-1R/IR and tyrosine kinases with antitumor activity.
Formula:
C28H29N5O3S
Purity:
99.11%
Color and Shape:
Liquid
Molecular weight:
515.63
Ref: TM-T68405
| 1mg | 546.00 € | ||
| 2mg | 783.00 € | ||
| 5mg | 1,189.00 € | ||
| 10mg | 1,606.00 € | ||
| 25mg | 2,437.00 € | ||
| 50mg | 3,205.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Indirubin Derivative E804
CAS:854171-35-0
Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with …
Formula:
C20H19N3O4
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T11654
| 2mg | 62.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GSK1904529A
CAS:1089283-49-7
GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
Formula:
C44H47F2N9O5S
Purity:
98.07% - 99%
Color and Shape:
Solid
Molecular weight:
851.96
Ref: TM-T6003
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00456
| 1mg | 5,169.00 € | ||
| 100µg | 799.00 € | ||
| 500µg | 3,089.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IGF1R/CD221 Protein, Mouse, Recombinant (His)
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Color and Shape:
Liquid
Molecular weight:
105.2 kDa (predicted); 172.5 kDa, 117.1 kDa and 49.8 kDa, corresponding to the single chain, α subunit and β subunit respectively (reducing condition, due to glycosylation)
Ref: TM-TMPY-06195
| 1mg | 4,356.00 € | ||
| 100µg | 689.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
80.59 kDa (alpha subunit) and 19.28 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 48-58 kDa (beta subunit) and 100-115 kDa (alpha subunit) and 130-150 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00658
| 1mg | 3,098.00 € | ||
| 100µg | 490.00 € | ||
| 500µg | 1,859.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00455
| 1mg | 3,098.00 € | ||
| 100µg | 490.00 € | ||
| 500µg | 1,859.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AG1024
CAS:65678-07-1
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
Formula:
C14H13BrN2O
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
305.17
Ref: TM-T2693
| 2mg | 41.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 233.00 € | ||
| 100mg | 351.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
NVP-ADW742
CAS:475488-23-4
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against …
Formula:
C28H31N5O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
453.58
Ref: TM-T6079
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 791.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
PQ401 hydrochloride (196868-63-0(free base))
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
Formula:
C18H17Cl2N3O2
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
378.25
Ref: TM-T4324
| 2mg | 35.00 € | ||
| 5mg | 47.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 277.00 € | ||
| 200mg | 402.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
NVP-AEW541
CAS:475489-16-8
NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and …
Formula:
C27H29N5O
Purity:
96.03% - 99.55%
Color and Shape:
Solid
Molecular weight:
439.55
Ref: TM-T6080
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
MAZ51
CAS:163655-37-6
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
Formula:
C21H18N2O
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
314.38
Ref: TM-T8496
| 1mg | 40.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 242.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | 599.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
XL228
CAS:898280-07-4
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM …
Formula:
C22H31N9O
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
437.54
Ref: TM-T17267
| 1mg | 55.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 569.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
