IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Found 86 products of "IGF-1R"
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MSDC-0602K
CAS:<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Formula:C19H16KNO5SPurity:99.42%Color and Shape:SolidMolecular weight:409.5AZ7550 hydrochloride
CAS:<p>AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formula:C27H32ClN7O2Purity:99.65%Color and Shape:SolidMolecular weight:522.04GIP (3-42), human
CAS:<p>Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.</p>Formula:C214H324N58O63SPurity:95.73%Color and Shape:SolidMolecular weight:4749.35Ganitumab
CAS:<p>Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.</p>Purity:100% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:145.70 kDaALK inhibitor 1
CAS:<p>ALK inhibitor 1 is a selective ALK kinase inhibitor.</p>Formula:C23H28BrN7O3SPurity:98.27%Color and Shape:SolidMolecular weight:562.48Robatumumab
CAS:<p>Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.</p>Purity:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)Color and Shape:LiquidGIP (human) acetate
<p>GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.</p>Purity:98.65%Color and Shape:SoildAcetyl Gastric Inhibitory Peptide (human)
CAS:<p>Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.</p>Formula:C228H340N60O67SColor and Shape:SolidMolecular weight:5025.6WAY-270250
CAS:<p>WAY-270250 is an IGF-1R/SRC inhibitor.</p>Formula:C18H16N2O2Purity:99.77%Color and Shape:SoildMolecular weight:292.33Insulin peglispro
CAS:<p>Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.</p>Formula:C370H566N104O110S4Color and Shape:SolidMolecular weight:8359.32IGF-1R inhibitor-2
CAS:<p>IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.</p>Formula:C24H24FN7O2Color and Shape:SolidMolecular weight:461.501Gastric Inhibitory Peptide (1-42) (porcine) TFA
<p>Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.</p>Formula:C225H342N60O66S·XCF3COOHColor and Shape:SolidMolecular weight:4975.55IGF-I (24-41)
CAS:<p>IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.</p>Formula:C88H133N27O28Purity:98%Color and Shape:SolidMolecular weight:2017.16ZIGIR
<p>ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.</p>Formula:C39H40N6O3Purity:98.34% - 99.32%Color and Shape:SolidMolecular weight:640.77GIP (1-30) amide,human
CAS:<p>GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.</p>Formula:C162H240N40O47SPurity:98%Color and Shape:SolidMolecular weight:3531.94AVE1642
<p>AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.</p>Color and Shape:Odour LiquidGIP, human
CAS:<p>Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.</p>Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.6[D-Ala2]-GIP (human)
CAS:<p>Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.</p>Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.58[Pro3]-GIP (Mouse)
<p>GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.</p>Formula:C225H342N62O64SPurity:98%Color and Shape:SolidMolecular weight:4971.62OI338
<p>OI338 is an orally available, ultralong-acting insulin analogue.</p>Formula:C260H403N65O84S6Color and Shape:SolidMolecular weight:5971.76
