IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
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AGL-2263
CAS:638213-98-6
AGL-2263 is a blocker of insulin receptor (IR)
Formula:
C17H10N2O5
Color and Shape:
Solid
Molecular weight:
322.27
Ref: TM-T14142
| 1mg | 70.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
ALK inhibitor 1
CAS:761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
Formula:
C23H28BrN7O3S
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
562.48
Ref: TM-T10285
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 621.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
HNMPA
CAS:132541-52-7
HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.
Formula:
C11H11O4P
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
238.18
Ref: TM-T21761
| 1mg | 51.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 648.00 € | ||
| 500mg | 1,371.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PQ401
CAS:196868-63-0
PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
Formula:
C18H16ClN3O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
341.79
Ref: TM-T2085
| 5mg | 73.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 444.00 € | ||
| 500mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Insulin efsitora alfa
CAS:2131038-11-2
Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel …
Color and Shape:
Liquid
Ref: TM-T77037
| 1mg | 397.00 € | ||
| 5mg | 1,037.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
NBI-31772
CAS:374620-70-9
NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki …
Formula:
C17H11NO7
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
341.27
Ref: TM-T8906
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 154.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 722.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
WAY-270250
CAS:852367-46-5
WAY-270250 is an IGF-1R/SRC inhibitor.
Formula:
C18H16N2O2
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
292.33
Ref: TM-T77624
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | 997.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
AZ7550 hydrochloride
CAS:2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R …
Formula:
C27H32ClN7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
522.04
Ref: TM-T13564L
| 1mg | 122.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 371.00 € | ||
| 25mg | 619.00 € | ||
| 50mg | 882.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
IGF1R/CD221 Protein, Mouse, Recombinant (His)
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Color and Shape:
Solid
Molecular weight:
105.2 kDa (predicted); 172.5 kDa, 117.1 kDa and 49.8 kDa, corresponding to the single chain, α subunit and β subunit respectively (reducing condition, due to glycosylation)
Ref: TM-TMPY-06195
| 1mg | 4,356.00 € | ||
| 100µg | 689.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Indirubin Derivative E804
CAS:854171-35-0
Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with …
Formula:
C20H19N3O4
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T11654
| 2mg | 62.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KW-2450 free base
CAS:904899-25-8
KW-2450 free base is a multiple inhibitor of IGF-1R/IR and tyrosine kinases with antitumor activity.
Formula:
C28H29N5O3S
Purity:
99.11%
Color and Shape:
Liquid
Molecular weight:
515.63
Ref: TM-T68405
| 1mg | 546.00 € | ||
| 2mg | 783.00 € | ||
| 5mg | 1,189.00 € | ||
| 10mg | 1,606.00 € | ||
| 25mg | 2,437.00 € | ||
| 50mg | 3,205.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00455
| 1mg | 3,098.00 € | ||
| 100µg | 490.00 € | ||
| 500µg | 1,859.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GSK1904529A
CAS:1089283-49-7
GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
Formula:
C44H47F2N9O5S
Purity:
98.07% - 99%
Color and Shape:
Solid
Molecular weight:
851.96
Ref: TM-T6003
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Solid
Molecular weight:
80.59 kDa (alpha subunit) and 19.28 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 48-58 kDa (beta subunit) and 100-115 kDa (alpha subunit) and 130-150 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00658
| 1mg | 3,098.00 € | ||
| 100µg | 490.00 € | ||
| 500µg | 1,859.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed …
Color and Shape:
Liquid
Molecular weight:
105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.
Ref: TM-TMPK-00456
| 1mg | 5,169.00 € | ||
| 100µg | 799.00 € | ||
| 500µg | 3,089.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Picropodophyllin
CAS:477-47-4
Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other …
Formula:
C22H22O8
Purity:
98.88% - 99.55%
Color and Shape:
Solid
Molecular weight:
414.41
Ref: TM-T6943
| 5mg | 68.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 314.00 € | ||
| 100mg | 528.00 € | ||
| 500mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS-536924
CAS:468740-43-4
BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest …
Formula:
C25H26ClN5O3
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
479.96
Ref: TM-T6419
| 1mg | 39.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 460.00 € | ||
| 100mg | 616.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PQ401 hydrochloride (196868-63-0(free base))
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
Formula:
C18H17Cl2N3O2
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
378.25
Ref: TM-T4324
| 2mg | 35.00 € | ||
| 5mg | 47.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 277.00 € | ||
| 200mg | 402.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
NVP-TAE 226
CAS:761437-28-9
NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, …
Formula:
C23H25ClN6O3
Purity:
98.07% - 99.17%
Color and Shape:
Solid
Molecular weight:
468.94
Ref: TM-T1918
| 1mg | 48.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK1838705A
CAS:1116235-97-2
GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.
Formula:
C27H29FN8O3
Purity:
100% - 99.63%
Color and Shape:
Solid
Molecular weight:
532.57
Ref: TM-T3079
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 262.00 € | ||
| 50mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
