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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Lapatinib Ditosylate

    CAS:
    <p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>
    Formula:C29H26ClFN4O4S·2C7H8O3S
    Purity:99.41%
    Color and Shape:Yellow Solid
    Molecular weight:925.46
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>
    Formula:C24H25FNNaO4
    Purity:98.54% - 99.56%
    Color and Shape:Light Yellow Solid Powder
    Molecular weight:433.45
  • Lapatinib ditosylate monohydrate

    CAS:
    <p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>
    Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2O
    Purity:98% - 99.41%
    Color and Shape:Colourless To Light-Yellow Crystal
    Molecular weight:943.47
  • Erlotinib

    CAS:
    <p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Formula:C22H23N3O4
    Purity:98.19% - 99.98%
    Color and Shape:White To Off-White Powder
    Molecular weight:393.44
  • Dexamethasone acetate

    CAS:
    <p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>
    Formula:C24H31FO6
    Purity:99.22% - 99.65%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:434.50
  • AZD7624

    CAS:
    <p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>
    Formula:C27H30FN5O3
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:491.56
  • Spironolactone

    CAS:
    <p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>
    Formula:C24H32O4S
    Purity:99.87%
    Color and Shape:White Powder
    Molecular weight:416.57
  • Chenodeoxycholic acid

    CAS:
    <p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>
    Formula:C24H40O4
    Purity:99.70% - 99.93%
    Color and Shape:White - Almost White Solid Powder
    Molecular weight:392.57
  • Itraconazole

    CAS:
    <p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>
    Formula:C35H38Cl2N8O4
    Purity:98% - 99.90%
    Color and Shape:Off-White Crystalline Solid
    Molecular weight:705.63
  • Vancomycin hydrochloride

    CAS:
    <p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>
    Formula:C66H76Cl3N9O24
    Purity:97.20% - 99.19%
    Color and Shape:Off White Powder
    Molecular weight:1485.71
  • Reserpine

    CAS:
    <p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>
    Formula:C33H40N2O9
    Purity:98.85% - 99.81%
    Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)
    Molecular weight:608.68
  • ZX-29

    CAS:
    <p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>
    Formula:C23H28ClN7O3S
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:518.03
  • LG-100064

    CAS:
    <p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>
    Formula:C23H26O3
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:350.45
  • Pyrazinamide

    CAS:
    <p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>
    Formula:C5H5N3O
    Purity:99.71% - 99.9%
    Color and Shape:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)
    Molecular weight:123.11
  • Raloxifene hydrochloride

    CAS:
    <p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>
    Formula:C28H28ClNO4S
    Purity:98% - 99.97%
    Color and Shape:Light Yellow Solid
    Molecular weight:510.044
  • Lomustine

    CAS:
    <p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>
    Formula:C9H16ClN3O2
    Purity:98.36% - 99.44%
    Color and Shape:Solid Solid
    Molecular weight:233.7
  • Crustecdysone

    CAS:
    <p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>
    Formula:C27H44O7
    Purity:99.06% - 99.67%
    Color and Shape:Canary Yellow Fine Powder
    Molecular weight:480.63
  • Matrine

    CAS:
    <p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>
    Formula:C15H24N2O
    Purity:97.16% - >99.99%
    Color and Shape:Solid
    Molecular weight:248.36
  • Nicardipine hydrochloride

    CAS:
    <p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>
    Formula:C26H30ClN3O6
    Purity:99.58% - 99.89%
    Color and Shape:Yellow Solid
    Molecular weight:515.99
  • Sorafenib tosylate

    CAS:
    <p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>
    Formula:C21H16ClF3N4O3·C7H8O3S
    Purity:99.24% - 99.94%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:637.03