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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • ZX-29

    CAS:
    <p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>
    Formula:C23H28ClN7O3S
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:518.03
  • Trimetazidine dihydrochloride

    CAS:
    <p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>
    Formula:C14H24Cl2N2O3
    Purity:99.58%
    Color and Shape:Crystalline Solid
    Molecular weight:339.258
  • LG-100064

    CAS:
    <p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>
    Formula:C23H26O3
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:350.45
  • Felodipine

    CAS:
    <p>Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.</p>
    Formula:C18H19Cl2NO4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:384.25
  • Sulfadoxine

    CAS:
    <p>Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial</p>
    Formula:C12H14N4O4S
    Purity:99.67%
    Color and Shape:White Or White Crystalline Powder
    Molecular weight:310.33
  • Sulindac

    CAS:
    <p>Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.</p>
    Formula:C20H17FO3S
    Purity:99.09% - 99.15%
    Color and Shape:Yellow Solid
    Molecular weight:356.41
  • Doxorubicin hydrochloride

    CAS:
    <p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>
    Formula:C27H29NO11·HCl
    Purity:98% - 99.52%
    Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
    Molecular weight:579.99
  • Oxidopamine hydrochloride

    CAS:
    <p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>
    Formula:C8H12ClNO3
    Purity:98.34% - 99.85%
    Color and Shape:Physical Description Beige Solid (Ntp 1992)
    Molecular weight:205.64
  • Oxidopamine hydrobromide

    CAS:
    <p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>
    Formula:C8H12BrNO3
    Purity:98.22% - 99.88%
    Color and Shape:Beige To Brown Fine Crystalline Powder
    Molecular weight:250.09
  • Carvedilol phosphate hemihydrate

    CAS:
    <p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>
    Formula:C24H26N2O4·5H2O·H3O4P
    Purity:99.24% - 99.98%
    Color and Shape:Solid
    Molecular weight:513.49
  • Erlotinib hydrochloride

    CAS:
    <p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Formula:C22H23N3O4·HCl
    Purity:99.78% - 99.85%
    Color and Shape:White Or Off-White Powder
    Molecular weight:429.9
  • Ezetimibe

    CAS:
    <p>Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.</p>
    Formula:C24H21F2NO3
    Purity:97.28% - 99.77%
    Color and Shape:Solid
    Molecular weight:409.43
  • Pyrazinamide

    CAS:
    <p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>
    Formula:C5H5N3O
    Purity:99.71% - 99.9%
    Color and Shape:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)
    Molecular weight:123.11
  • Baicalin

    CAS:
    <p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>
    Formula:C21H18O11
    Purity:90.08% - 99.32%
    Color and Shape:Yellow Powder
    Molecular weight:446.36
  • 9-ING-41

    CAS:
    <p>9-ING-41 is a glycogen synthase kinase-3 inhibitor.</p>
    Formula:C22H13FN2O5
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:404.35
  • Amiodarone hydrochloride

    CAS:
    <p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>
    Formula:C25H29I2NO3·HCl
    Purity:99.82% - ≥95%
    Color and Shape:White To Cream Crystalline Powder
    Molecular weight:681.78
  • Itraconazole

    CAS:
    <p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>
    Formula:C35H38Cl2N8O4
    Purity:98% - 99.90%
    Color and Shape:Off-White Crystalline Solid
    Molecular weight:705.63
  • Lomustine

    CAS:
    <p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>
    Formula:C9H16ClN3O2
    Purity:98.36% - 99.44%
    Color and Shape:Solid Solid
    Molecular weight:233.7
  • Taurine

    CAS:
    <p>Taurine (2-Aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues and is one of the constituents of bile acids. Cost-effective and quality-assured.</p>
    Formula:C2H7NO3S
    Purity:99.81% - 99.87%
    Color and Shape:White Crystalline Powder
    Molecular weight:125.15
  • Naproxen

    CAS:
    <p>Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic</p>
    Formula:C14H14O3
    Purity:99.6% - 99.89%
    Color and Shape:Crystals From Acetone-Hexane Solid
    Molecular weight:230.26