Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:509.67Cucurbitacin E
CAS:Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.Formula:C32H44O8Purity:98.88% - 99.87%Color and Shape:SolidMolecular weight:556.69Ref: TM-T5S1467
1mg56.00€5mg109.00€10mg168.00€25mg284.00€50mg423.00€100mg610.00€1mL*10mM (DMSO)133.00€Lucanthone hydrochloride
CAS:Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.Formula:C20H25ClN2OSColor and Shape:SolidMolecular weight:376.94Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formula:C27H20ClFN4O4Purity:98.31% - >99.99%Color and Shape:SolidMolecular weight:518.92Ref: TM-T2241
5mg52.00€10mg92.00€25mg146.00€50mg215.00€100mg334.00€200mg430.00€500mg705.00€1mL*10mM (DMSO)59.00€Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formula:C8H7NO2SPurity:99.33% - 99.79%Color and Shape:SolidMolecular weight:181.21Glucosamine sulfate
CAS:Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.25Rac-Belinostat
CAS:Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
Formula:C15H14N2O4SPurity:99.67% - 99.96%Color and Shape:SolidMolecular weight:318.35Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purity:≥98%Color and Shape:Brown PowderMolecular weight:676.83NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24Valinomycin
CAS:Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormula:C54H90N6O18Purity:95.37% - 97.16%Color and Shape:White SolidMolecular weight:1111.32Wortmannin
CAS:Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formula:C23H24O8Purity:95.84% - 99.77%Color and Shape:White SolidMolecular weight:428.43Ref: TM-T6283
1mg35.00€2mg50.00€5mg75.00€10mg113.00€25mg224.00€50mg385.00€100mg570.00€1mL*10mM (DMSO)84.00€Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formula:C24H25N5OPurity:98% - 99.06%Color and Shape:SolidMolecular weight:399.49Polydatin
CAS:Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.Formula:C20H22O8Purity:97.2% - 98.94%Color and Shape:White Fine PowderMolecular weight:390.38Tacrolimus monohydrate
CAS:Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.Formula:C44H71NO13Purity:97.07% - 98.05%Color and Shape:SolidMolecular weight:822.05Rasagiline Mesylate
CAS:Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.Formula:C13H17NO3SPurity:99.33%Color and Shape:White PowderMolecular weight:267.34DBEQ
CAS:DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formula:C22H20N4Purity:98.93% - ≥95%Color and Shape:SolidMolecular weight:340.42Ref: TM-T1969
2mg34.00€5mg52.00€10mg85.00€25mg152.00€50mg264.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€PHA-665752
CAS:PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.Formula:C32H34Cl2N4O4SPurity:97.05% - 98.82%Color and Shape:SolidMolecular weight:641.61Tubastatin A
CAS:Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formula:C20H21N3O2Purity:97.22% - 99.51%Color and Shape:SolidMolecular weight:335.4Ref: TM-T1966
10mg46.00€25mg60.00€50mg74.00€100mg105.00€200mg160.00€500mg259.00€1mL*10mM (DMSO)44.00€PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Tempol
CAS:Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formula:C9H18NO2Purity:97% - 99.98%Color and Shape:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMolecular weight:172.25Lys05
CAS:Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.Formula:C23H26Cl5N5Purity:99.13% - 99.55%Color and Shape:SolidMolecular weight:549.75Ataluren
CAS:Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formula:C15H9FN2O3Purity:99.16% - 99.84%Color and Shape:SolidMolecular weight:284.24Ref: TM-T1805
5mg35.00€10mg54.00€25mg88.00€50mg117.00€100mg178.00€200mg213.00€500mg359.00€1mL*10mM (DMSO)46.00€MK-2206 dihydrochloride
CAS:MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormula:C25H23Cl2N5OPurity:99.228% - 99.94%Color and Shape:SolidMolecular weight:480.39Ref: TM-T1952
2mg34.00€5mg49.00€10mg66.00€25mg90.00€50mg137.00€100mg205.00€200mg334.00€500mg552.00€1mL*10mM (DMSO)52.00€SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formula:C10H9NO2SPurity:98% - 99.92%Color and Shape:SolidMolecular weight:207.25Ref: TM-T1902
5mg48.00€10mg54.00€25mg90.00€50mg161.00€100mg251.00€200mg378.00€500mg627.00€1mL*10mM (DMSO)50.00€L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formula:C20H14ClN3OPurity:≥95%Color and Shape:SolidMolecular weight:347.8NVP-AEW541
CAS:NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormula:C27H29N5OPurity:98.7% - 99.86%Color and Shape:SolidMolecular weight:439.55Retro-2
CAS:Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.
Formula:C19H16N2OSPurity:98.15%Color and Shape:SolidMolecular weight:320.41Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purity:99.14% - 99.95%Color and Shape:SolidMolecular weight:416.46Ref: TM-T6S1917
5mg67.00€10mg90.00€25mg190.00€50mg286.00€100mg429.00€500mg982.00€1mL*10mM (DMSO)74.00€Fasudil hydrochloride hydrate
CAS:Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.Formula:C28H38Cl2N6O5S2Color and Shape:SolidMolecular weight:673.67Diosgenin glucoside
CAS:Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis
Formula:C33H52O8Purity:97.17% - 99.44%Color and Shape:SolidMolecular weight:576.76Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purity:98.53% - 99%Color and Shape:SolidMolecular weight:344.32Bicyclol
CAS:Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.
Formula:C19H18O9Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:390.34Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.Formula:C29H25F4N3O5SPurity:99.3% - 99.85%Color and Shape:SolidMolecular weight:603.58Sanguinarine
CAS:Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.Formula:C20H14NO4Purity:99.04% - 99.76%Color and Shape:SolidMolecular weight:332.33RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormula:C17H20N4O2Purity:99.30%Color and Shape:SolidMolecular weight:312.37Sitagliptin phosphate
CAS:Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.Formula:C16H18F6N5O5PPurity:99.72% - 99.91%Color and Shape:White SolidMolecular weight:505.31FIPI HCl
CAS:FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.Formula:C23H25ClFN5O2Color and Shape:SolidMolecular weight:457.93Brefeldin A
CAS:Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).Formula:C16H24O4Purity:96.45% - 99.89%Color and Shape:White SolidMolecular weight:280.36Lapatinib tosylate
CAS:Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Formula:C36H34ClFN4O7S2Color and Shape:SolidMolecular weight:753.26JZL195
CAS:JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.Formula:C24H23N3O5Purity:99.81%Color and Shape:SolidMolecular weight:433.46Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purity:99.04% - >99.99%Color and Shape:SolidMolecular weight:228.2Idarubicin
CAS:Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.Formula:C26H27NO9Color and Shape:SolidMolecular weight:497.49Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:98.91% - 99.96%Color and Shape:SolidMolecular weight:533.95GSK2606414
CAS:GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.Formula:C24H20F3N5OPurity:98% - >99.99%Color and Shape:SolidMolecular weight:451.44ABT-737
CAS:ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.Formula:C42H45ClN6O5S2Purity:98.15% - >99.99%Color and Shape:SolidMolecular weight:813.43Dinoprost tromethamine salt
CAS:Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.Formula:C24H45NO8Purity:99.73% - 99.88%Color and Shape:Natural Form Crystals SolidMolecular weight:475.62Calcimycin
CAS:Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.Formula:C29H37N3O6Purity:98%Color and Shape:SolidMolecular weight:523.62Sophocarpine
CAS:Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formula:C15H22N2OPurity:99.89%Color and Shape:SolidMolecular weight:246.35
