Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1483 products of "Autophagy"
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Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69BMS-582949 hydrochloride
CAS:The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).Formula:C22H27ClN6O2Purity:97.57% - 98.75%Color and Shape:SolidMolecular weight:442.95Tazarotene
CAS:Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formula:C21H21NO2SPurity:97.01% - 99.14%Color and Shape:White SolidMolecular weight:351.46Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purity:96.39% - 99.29%Color and Shape:SolidMolecular weight:394.42BIA 10-2474
CAS:BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formula:C16H20N4O2Purity:99.27%Color and Shape:SolidMolecular weight:300.36Pirarubicin
CAS:Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.Formula:C32H37NO12Purity:97.80% - 99.15%Color and Shape:Red Crystalline PowderMolecular weight:627.64kaempferide
CAS:kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formula:C16H12O6Purity:98.4% - 99.66%Color and Shape:SolidMolecular weight:300.26SR12813
CAS:SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Formula:C24H42O7P2Purity:99.43%Color and Shape:SolidMolecular weight:504.53GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formula:C21H27N7O3Purity:98.07% - 99.77%Color and Shape:SolidMolecular weight:425.48Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurity:99.45%Color and Shape:SolidMolecular weight:474.91Cabergoline diphosphate
CAS:Cabergoline, a D2 receptor agonist, treats prolactinomas by normalizing prolactin levels.Formula:C26H43N5O10P2Color and Shape:SolidMolecular weight:647.6PF-4708671
CAS:<p>PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).</p>Formula:C19H21F3N6Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:390.41Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83BI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formula:C19H23F2N5O2Purity:98.51% - 99.43%Color and Shape:SolidMolecular weight:391.42VLX600
CAS:VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formula:C17H15N7Purity:98.62%Color and Shape:SolidMolecular weight:317.35Ganoderic acid A
CAS:Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formula:C30H44O7Purity:99.31% - ≥95%Color and Shape:SolidMolecular weight:516.67PAC-1
CAS:<p>PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.</p>Formula:C23H28N4O2Purity:96.78% - 99.77%Color and Shape:SolidMolecular weight:392.49Bromocriptine mesylate
CAS:Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)Formula:C33H44BrN5O8SPurity:99.85% - 99.96%Color and Shape:White SolidMolecular weight:750.7Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purity:98.92% - 99.67%Color and Shape:White Crystal PowderMolecular weight:608.72Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purity:99.56% - >99.99%Color and Shape:SolidMolecular weight:425.42SR9011
CAS:SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).Formula:C23H31ClN4O3SPurity:99.64% - 99.65%Color and Shape:SolidMolecular weight:479.042-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:302.41Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33Fendiline
CAS:Fendiline: coronary vasodilator, calcium blocker, potential antiarrhythmic/antianginal.Formula:C23H25NColor and Shape:SolidMolecular weight:315.45DMOG
CAS:<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formula:C38H35N5O6S2Purity:99.80% - >99.99%Color and Shape:White SolidMolecular weight:721.84Alirocumab
CAS:Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.Purity:95% - 97.1% (SDS-PAGE); 96.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.2 kDaAdezmapimod
CAS:Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formula:C21H16FN3OSPurity:99.42% - 99.93%Color and Shape:White SolidMolecular weight:377.43Heparin sodium salt
CAS:Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Formula:C26H42N2NaO37S5Purity:98%Color and Shape:SolidMolecular weight:1157.89Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.50Gambogic Acid
CAS:Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.Formula:C38H44O8Purity:97.16% - 98.67%Color and Shape:SolidMolecular weight:628.75Ruxolitinib phosphate
CAS:<p>Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.</p>Formula:C17H21N6O4PPurity:98% - >99.99%Color and Shape:SolidMolecular weight:404.36Perifosine
CAS:Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formula:C25H52NO4PPurity:99.80 - >99.99%Color and Shape:SolidMolecular weight:461.66GANT 61
CAS:<p>GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.</p>Formula:C27H35N5Purity:97.59% - >99.99%Color and Shape:SolidMolecular weight:429.6UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purity:99.82%Color and Shape:SolidMolecular weight:436.58Dansylcadaverine
CAS:Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.Formula:C17H25N3O2SPurity:98.33% - 99.6%Color and Shape:SolidMolecular weight:335.46Pemetrexed disodium hemipenta hydrate
CAS:<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Formula:C20H21N5O6·2NaH2OPurity:98.76%Color and Shape:SolidMolecular weight:518.43SD 0006
CAS:SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purity:95.10% - 99.3% （SEC-HPLC）Color and Shape:LiquidMolecular weight:145 kDaDacinostat
CAS:LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.Formula:C22H25N3O3Purity:95.28% - 97.88%Color and Shape:SolidMolecular weight:379.45Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
Myristoylated autocamtide-2-related inhibitory peptide acetate is a cell-permeable CaM kinase II inhibitor.Formula:C80H146N22O22Purity:97.03%Color and Shape:SolidMolecular weight:1768.15Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.4% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45SR-18292
CAS:SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.Formula:C23H30N2O2Purity:99.16% - 99.91%Color and Shape:SolidMolecular weight:366.5SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Formula:C19H20FN5OPurity:99.13% - 99.68%Color and Shape:SolidMolecular weight:353.39Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1030.29CA77.1
CAS:CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).Formula:C16H12ClN3OPurity:99.50%Color and Shape:SolidMolecular weight:297.74
