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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Hydroxyurea

    CAS:
    <p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>
    Formula:CH4N2O2
    Purity:99.85% - 99.92%
    Color and Shape:Solid
    Molecular weight:76.05
  • Glibenclamide

    CAS:
    <p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>
    Formula:C23H28ClN3O5S
    Purity:99.05% - 99.75%
    Color and Shape:Solid
    Molecular weight:494.00
  • Spironolactone

    CAS:
    <p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>
    Formula:C24H32O4S
    Purity:99.87%
    Color and Shape:White Powder
    Molecular weight:416.57
  • BIX 02565

    CAS:
    <p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>
    Formula:C26H30N6O2
    Purity:97.44% - 99.7%
    Color and Shape:Solid
    Molecular weight:458.56
  • Erlotinib

    CAS:
    <p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Formula:C22H23N3O4
    Purity:98.19% - 99.98%
    Color and Shape:White To Off-White Powder
    Molecular weight:393.44
  • Lapatinib ditosylate monohydrate

    CAS:
    <p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>
    Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2O
    Purity:98% - 99.41%
    Color and Shape:Colourless To Light-Yellow Crystal
    Molecular weight:943.47
  • Raloxifene hydrochloride

    CAS:
    <p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>
    Formula:C28H28ClNO4S
    Purity:98% - 99.97%
    Color and Shape:Light Yellow Solid
    Molecular weight:510.044
  • Dexamethasone acetate

    CAS:
    <p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>
    Formula:C24H31FO6
    Purity:99.22% - 99.65%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:434.50
  • Oxaliplatin

    CAS:
    <p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>
    Formula:C8H14N2O4Pt
    Purity:97% - 99.93%
    Color and Shape:Solid
    Molecular weight:397.29
  • Sunitinib Malate

    CAS:
    <p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>
    Formula:C26H33FN4O7
    Purity:98% - 99.26%
    Color and Shape:Solid
    Molecular weight:532.56
  • Chenodeoxycholic acid

    CAS:
    <p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>
    Formula:C24H40O4
    Purity:99.70% - 99.93%
    Color and Shape:White - Almost White Solid Powder
    Molecular weight:392.57
  • Avermectin B1

    CAS:
    <p>Avermectin B1 is served as anthelmintic and insecticide.</p>
    Formula:C48H72O14
    Purity:mixture - mixture
    Color and Shape:White Powder
    Molecular weight:873.09
  • Reserpine

    CAS:
    <p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>
    Formula:C33H40N2O9
    Purity:98.85% - 99.81%
    Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)
    Molecular weight:608.68
  • Dexamethasone

    CAS:
    <p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>
    Formula:C22H29FO5
    Purity:98% - 99.91%
    Color and Shape:Crystals From Ether (Ntp 1992)
    Molecular weight:392.46
  • Thalidomide

    CAS:
    <p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>
    Formula:C13H10N2O4
    Purity:98.88% - 99.88%
    Color and Shape:White Solid
    Molecular weight:258.23
  • Doxazosin mesylate

    CAS:
    <p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>
    Formula:C24H29N5O8S
    Purity:99.92%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:547.58
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>
    Formula:C24H25FNNaO4
    Purity:98.54% - 99.56%
    Color and Shape:Light Yellow Solid Powder
    Molecular weight:433.45
  • Pictilisib dimethanesulfonate

    CAS:
    <p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>
    Formula:C25H35N7O9S4
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:705.85
  • Doxorubicin hydrochloride

    CAS:
    <p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>
    Formula:C27H29NO11·HCl
    Purity:98% - 99.52%
    Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
    Molecular weight:579.99
  • Colistin sulfate

    CAS:
    <p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>
    Formula:C53H100N16O17S
    Purity:98%
    Color and Shape:Powder
    Molecular weight:1253.51