Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
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GSK2606414
CAS:GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.Formula:C24H20F3N5OPurity:98% - >99.99%Color and Shape:SolidMolecular weight:451.44Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Formula:C21H23N3O2Purity:97.2% - 99.81%Color and Shape:Yellow SolidMolecular weight:349.43Crizotinib
CAS:<p>Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.</p>Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:SolidMolecular weight:450.34SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formula:C19H12Cl2N2O2Purity:98.9% - 99.13%Color and Shape:SolidMolecular weight:371.22(+)-JQ-1
CAS:<p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>Formula:C23H25ClN4O2SPurity:97.57% - ≥95%Color and Shape:SolidMolecular weight:456.99Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Formula:C20H18O10Purity:98.8% - 99.33%Color and Shape:SolidMolecular weight:418.35LYS01
CAS:<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Formula:C23H23Cl2N5Purity:98.28%Color and Shape:SolidMolecular weight:440.37Meglutol
CAS:Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.Formula:C6H10O5Purity:99.73% - 99.94%Color and Shape:SolidMolecular weight:162.14MRT68921 dihydrochloride
CAS:MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).Formula:C25H36Cl2N6OPurity:98.91% - 99.92%Color and Shape:SolidMolecular weight:507.499Berberine hydrogen sulphate
CAS:<p>Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.</p>Formula:C20H19NO8SPurity:99% - 99.79%Color and Shape:Yellow Crystals Off-White To Yellow PowderMolecular weight:433.434,4'-Dimethoxychalcone
CAS:<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Formula:C17H16O3Purity:99.57%Color and Shape:SolidMolecular weight:268.31Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Formula:C27H31Cl3N6OPurity:98.73% - ≥98%Color and Shape:SolidMolecular weight:561.93Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.12MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formula:C26H41N3O5Purity:95% - 99.99%Color and Shape:White To Off-White PowderMolecular weight:475.62Vps34-IN-1
CAS:<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Formula:C21H24ClN7OPurity:97.04%Color and Shape:SolidMolecular weight:425.91SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purity:99.42% - 99.79%Color and Shape:SolidMolecular weight:443.85Galangin
CAS:<p>Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.</p>Formula:C15H10O5Purity:98.24% - 99.93%Color and Shape:Yellowish Needle-Like CrystalMolecular weight:270.2410058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purity:98% - 99.87%Color and Shape:SolidMolecular weight:249.35AZ304
CAS:<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Formula:C27H25N5O2Purity:99.82%Color and Shape:SolidMolecular weight:451.52KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Formula:C17H21N3O6S2Purity:99.88% - ≥95%Color and Shape:SolidMolecular weight:427.5
