Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 86 products of "Endothelin Receptor"
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Enrasentan
CAS:Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure and protects myocardial function.Formula:C29H30O8Purity:97.9% - 98.39%Color and Shape:SolidMolecular weight:506.54Sulfisoxazole
CAS:Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.Formula:C11H13N3O3SPurity:99.87% - 99.98%Color and Shape:White To Cream PowderMolecular weight:267.30[Lys4] Sarafotoxin S6c
CAS:[Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.Formula:C105H153N27O36S5Color and Shape:SolidMolecular weight:2529.82[Ala2] Endothelin-3, human
CAS:[Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.Formula:C120H166N26O32S4Color and Shape:SolidMolecular weight:2613.02Sarafotoxin S6a
CAS:Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.Formula:C105H156N28O34S5Purity:98%Color and Shape:SolidMolecular weight:2514.85Endothelin 1 (swine, human), Alexa Fluor 488-labeled
Synthetic human/swine Endothelin 1 peptide, tagged with Alexa Fluor 488, acts as a strong vasoconstrictor via ET A/B receptors.Color and Shape:SolidMolecular weight:2848.4Sarafotoxin S6c
CAS:Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).Formula:C103H147N27O37S5Purity:98%Color and Shape:SolidMolecular weight:2516Nebentan
CAS:<p>Nebentan (YM598) is an oral, selective ETA antagonist; Ki: 0.697 nM (ETA), 569 nM (ETB); may slow cor pulmonale, myocardial infarction.</p>Formula:C24H21N5O5SColor and Shape:SolidMolecular weight:491.52Sarafotoxin S6b
CAS:non-selective endothelin receptor agonistFormula:C110H163N27O34S5Purity:98%Color and Shape:SolidMolecular weight:2567.96Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.Formula:C128H205N45O39S2Purity:98%Color and Shape:SolidMolecular weight:3062.41ACT-373898
CAS:<p>ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1</p>Formula:C15H17BrN4O5SColor and Shape:SolidMolecular weight:445.29PD 142893
CAS:PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.Formula:C50H65N7O10Purity:98%Color and Shape:SolidMolecular weight:924.09IRL-1038
CAS:<p>ETB endothelin receptor antagonist</p>Formula:C68H92N14O15S2Purity:98%Color and Shape:SolidMolecular weight:1409.67IRL-1620
CAS:IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).Formula:C86H117N17O27Purity:98%Color and Shape:SolidMolecular weight:1820.974[Ala1,3,11,15]-Endothelin
CAS:Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).Formula:C109H163N25O32SPurity:98%Color and Shape:SolidMolecular weight:2368BQ-123 TFA
BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.Formula:C33H43F3N6O9Color and Shape:SolidMolecular weight:724.72IRL-3630
CAS:IRL 3460 is an enantiomer.Formula:C31H40N4O6SPurity:98%Color and Shape:SolidMolecular weight:596.74SB234551
CAS:SB234551 is a selective antagonist of endothelin ETA receptor.Formula:C34H34N2O9Color and Shape:SolidMolecular weight:614.64Atrial natriuretic factor (1-28) (rat) TFA
ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.Formula:C130H206N45F3O41S2Purity:98%Color and Shape:SolidMolecular weight:3176.43Endothelin-2 (49-69), human TFA
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.Formula:C117H161N26F3O34S4Purity:98%Color and Shape:SolidMolecular weight:2660.94
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![[Ala2] Endothelin-3, human](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76305.webp&w=3840&q=75)
![[Ala1,3,11,15]-Endothelin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2099.webp&w=3840&q=75)
