Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
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Sulfisoxazole
CAS:127-69-5
Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin …
Formula:
C11H13N3O3S
Purity:
99.98%
Color and Shape:
White To Cream Powder
Molecular weight:
267.3
Ref: TM-T0750
| 1g | 73.00 € | ||
| 200mg | 37.00 € | ||
| 500mg | 52.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Patecibart
CAS:2642374-04-5
Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T81538
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Enrasentan
CAS:167256-08-8
Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure …
Formula:
C29H30O8
Purity:
97.90% - 97.96%
Color and Shape:
Solid
Molecular weight:
506.54
Ref: TM-T31640
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 1,004.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
BQ-3020 ammonium
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] …
Formula:
C96H140N20O25S·xNH3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
2006.32 (free base)
Ref: TM-T78096
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Myriceric acid C
CAS:162059-94-1
Myriceric acid C has cytotoxic activity against human lung carcinoma and breast carcinoma.
Formula:
C48H60O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
796.98
Ref: TM-TN4606
| 5mg | 670.00 € | ||
| 1mL*10mM (DMSO) | 1,020.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Nebentan potassium
CAS:342005-82-7
Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is …
Formula:
C24H20KN5O5S
Purity:
98.92%
Color and Shape:
Solid
Molecular weight:
529.61
Ref: TM-T36008
| 1mg | 91.00 € | ||
| 2mg | 119.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 306.00 € | ||
| 25mg | 540.00 € | ||
| 50mg | 865.00 € | ||
| 100mg | 1,174.00 € | ||
| 500mg | 2,357.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Aprocitentan
CAS:1103522-45-7
Aprocitentan (ACT-132577) is ETA and ETB antagonist .
Formula:
C16H14Br2N6O4S
Purity:
99.17%
Color and Shape:
Solid
Molecular weight:
546.19
Ref: TM-T7817
| 1mg | 57.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 303.00 € | ||
| 50mg | 428.00 € | ||
| 100mg | 638.00 € | ||
| 200mg | 862.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Macitentan
CAS:441798-33-0
Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary …
Formula:
C19H20Br2N6O4S
Purity:
100% - 99.81%
Color and Shape:
Solid
Molecular weight:
588.27
Ref: TM-T2561
| 10mg | 43.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 81.00 € | ||
| 500mg | 171.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Darusentan
CAS:171714-84-4
Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and …
Formula:
C22H22N2O6
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
410.43
Ref: TM-T5458
| 1mg | 49.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 498.00 € | ||
| 100mg | 721.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Atrasentan
CAS:173937-91-2
Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and …
Formula:
C29H38N2O6
Purity:
99.08% - 99.08%
Color and Shape:
Solid
Molecular weight:
510.62
Ref: TM-TQ0259
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sparsentan
CAS:254740-64-2
Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin …
Formula:
C32H40N4O5S
Purity:
97.94% - 98.75%
Color and Shape:
Solid
Molecular weight:
592.75
Ref: TM-T5355
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 370.00 € | ||
| 200mg | 525.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS 182874 hydrochloride
CAS:1215703-04-0
BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.
Formula:
C17H20ClN3O3S
Purity:
97.01%
Color and Shape:
Solid
Molecular weight:
381.88
Ref: TM-T21790
| 1mg | 79.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 486.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 149.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sitaxsentan sodium
CAS:210421-74-2
Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.
Formula:
C18H14ClN2O6S2·Na
Purity:
98.39% - ≥95%
Color and Shape:
Solid
Molecular weight:
476.89
Ref: TM-T6672
| 5mg | 35.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 98.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 263.00 € | ||
| 200mg | 383.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BQ-123
CAS:136553-81-6
BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase …
Formula:
C31H42N6O7
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
610.7
Ref: TM-T6792
| 1mg | 87.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 536.00 € | ||
| 50mg | 764.00 € | ||
| 100mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 268.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bosentan (hydrate)
CAS:157212-55-0
Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A …
Formula:
C27H29N5O6S·H2O
Purity:
99.31% - 99.86%
Color and Shape:
White Powder
Molecular weight:
569.63
Ref: TM-T6265
| 25mg | 51.00 € | ||
| 50mg | 64.00 € | ||
| 100mg | 99.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RO 46-8443
CAS:175556-12-4
RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.
Formula:
C31H35N3O8S
Purity:
98.5% - 99.77%
Color and Shape:
Solid
Molecular weight:
609.69
Ref: TM-T3474
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,087.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ambrisentan
CAS:177036-94-1
Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not …
Formula:
C22H22N2O4
Purity:
99.65% - 99.86%
Color and Shape:
Solid
Molecular weight:
378.42
Ref: TM-T1655
| 5mg | 35.00 € | ||
| 10mg | 44.00 € | ||
| 25mg | 75.00 € | ||
| 50mg | 103.00 € | ||
| 100mg | 152.00 € | ||
| 200mg | 218.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ro 46-2005
CAS:150725-87-4
Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 …
Formula:
C23H27N3O6S
Purity:
98.02% - 98.8%
Color and Shape:
Solid
Molecular weight:
473.54
Ref: TM-T3194
| 5mg | 44.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 292.00 € | ||
| 200mg | 422.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bosentan
CAS:147536-97-8
Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.
Formula:
C27H29N5O6S
Purity:
100% - 99.8%
Color and Shape:
Pale Yellow To Off-White Solid
Molecular weight:
551.614
Ref: TM-T6264
| 10mg | 38.00 € | ||
| 25mg | 55.00 € | ||
| 50mg | 80.00 € | ||
| 100mg | 124.00 € | ||
| 200mg | 202.00 € | ||
| 500mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Zibotentan
CAS:186497-07-4
Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting …
Formula:
C19H16N6O4S
Purity:
97.00% - 99.34%
Color and Shape:
Solid
Molecular weight:
424.43
Ref: TM-T6258
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 8 Jan 2025
