DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 802 products of "DNA/RNA Synthesis"
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Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurity:98.68% - 99.64%Color and Shape:SolidMolecular weight:401.46Uridine-5'-diphosphate disodium salt
CAS:UDP disodium salt is a P2Y6 agonist (EC50 = 13 nM), enhances inflammation, phagocytosis, vasoconstriction, and inhibits P2Y14.Formula:C9H12N2Na2O12P2Purity:98.76% - >99.99%Color and Shape:White Fine CrystalsMolecular weight:448.12Cidofovir
CAS:Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。Formula:C8H14N3O6PPurity:99.24% - 99.76%Color and Shape:Fluffy White PowderMolecular weight:279.19TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Formula:C19H18BrIN4O2Purity:98.38% - 98.73%Color and Shape:SolidMolecular weight:541.18Ref: TM-T8119
1mg46.00€2mg59.00€5mg88.00€10mg152.00€25mg288.00€50mg520.00€100mg750.00€500mg1,521.00€1mL*10mM (DMSO)105.00€Quinizarin
CAS:Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product
Formula:C14H8O4Purity:95.02%Color and Shape:Leaves Yellow Red And Needles Dark Red Solid Leaves Or NeedlesMolecular weight:240.21Sodium Camptothecin
CAS:Sodium Camptothecin: plant-derived, antitumor, inhibits RNA/DNA synthesis, disrupts viral DNA.Formula:C20H18N2NaO5Purity:98.93%Color and Shape:SolidMolecular weight:389.36TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Formula:C13H12Cl2N4Purity:96.05% - 99.82%Color and Shape:SolidMolecular weight:295.17DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2C/EBPα inducer 1
CAS:C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation viaFormula:C20H12FN3O4Purity:98.99%Color and Shape:SolidMolecular weight:377.33BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41TH287
CAS:TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Formula:C11H10Cl2N4Purity:97.73% - 99%Color and Shape:SolidMolecular weight:269.13Ref: TM-T2069
1mg37.00€2mg48.00€5mg72.00€10mg96.00€25mg188.00€50mg366.00€100mg545.00€1mL*10mM (DMSO)79.00€N2-methylguanine
CAS:N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.Formula:C6H7N5OPurity:99.86%Color and Shape:SolidMolecular weight:165.15Adenine hydrochloride
CAS:Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.
Formula:C5H5N5·HClPurity:98.86%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:171.59Nimustine Hydrochloride
CAS:Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.Formula:C9H14Cl2N6O2Purity:98.80%Color and Shape:SolidMolecular weight:309.15Ref: TM-T5017
2mgTo inquire5mg52.00€10mg74.00€25mg97.00€50mg160.00€100mg283.00€200mgTo inquire1mL*10mM (DMSO)52.00€TH5427
CAS:TH5427 is a lead NUDT5 inhibitor(MG assay IC50 = 29 nM).Formula:C20H20Cl2N8O3Purity:99.54%Color and Shape:SolidMolecular weight:491.33Ref: TM-T39785L
1mg92.00€2mg130.00€5mg200.00€10mg290.00€25mg495.00€50mg623.00€100mg842.00€200mg1,134.00€Anisomycin
CAS:Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.Formula:C14H19NO4Purity:98.33% - 99.81%Color and Shape:White Crystalline SolidMolecular weight:265.3SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Formula:C16H12F3N3SPurity:97.98% - >99.99%Color and Shape:SolidMolecular weight:335.35CX-5461 dihydrochloride
CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).Formula:C27H29Cl2N7O2SColor and Shape:SolidMolecular weight:586.54Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Formula:C31H35Cl3N8O5Purity:99.69%Color and Shape:SolidMolecular weight:706.02Madrasin
CAS:Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Formula:C16H17N5O2Purity:99.06% - 99.61%Color and Shape:SolidMolecular weight:311.34Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Formula:C35H33FN6O3Purity:99.77%Color and Shape:SolidMolecular weight:604.67Ref: TM-T16703
1mg71.00€2mg92.00€5mg152.00€10mg236.00€25mg380.00€50mg530.00€100mg708.00€1mL*10mM (DMSO)212.00€Simeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Formula:C38H47N5O7S2Purity:99.45% - 99.92%Color and Shape:SolidMolecular weight:749.94Favipiravir
CAS:Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.Formula:C5H4FN3O2Purity:97.32% - 99.90%Color and Shape:SolidMolecular weight:157.1O6-Benzylguanine
CAS:O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.Formula:C12H11N5OPurity:98.9%Color and Shape:Solid CrystallineMolecular weight:241.25Myoseverin
CAS:Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.
Formula:C24H28N6O2Purity:99.25%Color and Shape:SolidMolecular weight:432.52Raltitrexed
CAS:Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.Formula:C21H22N4O6SPurity:98.99% - 99.29%Color and Shape:Yellow Crystalline PowderMolecular weight:458.49CB-6644
CAS:CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.Formula:C29H34ClFN4O5Purity:96.33% - 99.85%Color and Shape:SolidMolecular weight:573.06Ref: TM-T10693
1mg205.00€5mg416.00€10mg533.00€25mg748.00€50mg973.00€100mg1,260.00€1mL*10mM (DMSO)525.00€Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Formula:C12H13FN4O5Color and Shape:SolidMolecular weight:312.257Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formula:C41H44N4O10SPurity:98.11%Color and Shape:SolidMolecular weight:784.87Simeprevir sodium
CAS:Simeprevir is a drug for the treatment and cure of hepatitis C.Formula:C38H46N5NaO7S2Purity:98%Color and Shape:SolidMolecular weight:771.92L189
CAS:L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).Formula:C11H10N4OSPurity:97.37%Color and Shape:SolidMolecular weight:246.29Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Ref: TM-T4226
1mg34.00€5mg71.00€10mg92.00€25mg152.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41Ro5-3335
CAS:Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.Formula:C13H10ClN3OPurity:99.42% - 99.87%Color and Shape:SolidMolecular weight:259.69Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47IMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Formula:C25H29F2N5OPurity:98.48% - 99.52%Color and Shape:SolidMolecular weight:453.53Ref: TM-T9350
1mg137.00€2mg178.00€5mg268.00€10mg444.00€25mg790.00€50mg1,063.00€1mL*10mM (DMSO)294.00€Cedazuridine hydrochloride
Cedazuridine (E7727) hydrochloride is an oral cancer research drug blocking cytidine deaminase (IC50=0.4μM).Formula:C9H15ClF2N2O5Color and Shape:SolidMolecular weight:304.68Fosifloxuridine nafalbenamide
CAS:Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.
Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53Gadodiamide
CAS:Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.Formula:C16H26GdN5O8Purity:99.86% - 99.93%Color and Shape:SolidMolecular weight:573.66Nemorubicin HCL
CAS:Nemorubicin HCL, a PNU152243A salt, acts on resistant tumors via topoisomerase I inhibition and targets NER pathway upregulated cells.Formula:C32H38ClNO13Color and Shape:SolidMolecular weight:680.1CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formula:C9H6N2O4Purity:98.27% - 98.98%Color and Shape:Brown PowderMolecular weight:206.15AT-130
CAS:AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.Formula:C22H22BrN3O5Purity:97.81%Color and Shape:SolidMolecular weight:488.33Ref: TM-T26674
1mg39.00€5mg86.00€10mg124.00€25mg215.00€50mg320.00€100mg482.00€200mg662.00€1mL*10mM (DMSO)93.00€RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purity:99.63% - 99.86%Color and Shape:SolidMolecular weight:433.28Ref: TM-T2628
1mg70.00€2mg92.00€5mg152.00€10mg266.00€25mg413.00€50mg605.00€100mg863.00€1mL*10mM (DMSO)166.00€6-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。
Formula:C21H20N6Purity:98% - 98.01%Color and Shape:SolidMolecular weight:356.42MTOB
CAS:MTOB, a CtBP substrate, inhibits CtBP-linked cancer activity in cells/mice and regulates TCF-4, affecting CSC proliferation.Formula:C5H7NaO3SPurity:98.23%Color and Shape:SolidMolecular weight:170.16L-Asparaginase
CAS:L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.Formula:NAPurity:97%Color and Shape:SolidMolecular weight:N/A
