PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
- AMPK(162 products)
- ATM/ATR(71 products)
- DNA-PK(50 products)
- EGFR(597 products)
- MELK(7 products)
- PDK(9 products)
- PI3K(235 products)
- S6 Kinase(5 products)
- gsk-3(107 products)
- mTOR(164 products)
Show 2 more subcategories
Found 1007 products for "PI3K/Akt/mTOR Signaling".
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E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurity:99.87% - 99.98%Color and Shape:White SolidMolecular weight:474.44PI-3065
CAS:PI-3065 is a novel potent and selective PI3K p110δ inhibitor.Formula:C27H31FN6OSPurity:99.84% - ≥95%Color and Shape:SolidMolecular weight:506.64RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formula:C32H36N8O3Purity:97.16% - 98.72%Color and Shape:SolidMolecular weight:580.68Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formula:C26H26FN7O2Purity:99.81% - >99.99%Color and Shape:White SolidMolecular weight:487.53Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Formula:C24H25ClFN5O2Purity:99.4% - 99.72%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2483
1mg35.00€2mg50.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg120.00€25mg170.00€50mg215.00€100mg334.00€200mg421.00€500mg692.00€CC-115
CAS:CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).Formula:C16H16N8OPurity:86.79% - 99.01%Color and Shape:SolidMolecular weight:336.35Ref: TM-T3541
10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire1mg34.00€5mg59.00€1mL*10mM (DMSO)66.00€GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Formula:C18H19N5Purity:98.87%Color and Shape:SolidMolecular weight:305.38Ref: TM-T24111
1mg63.00€5mg114.00€1mL*10mM (DMSO)128.00€10mg172.00€25mg279.00€50mg406.00€100mg572.00€Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFormula:C23H25ClFN5O3Purity:98.89% - 99.83%Color and Shape:SolidMolecular weight:473.93Bikinin
CAS:Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.Formula:C9H9BrN2O3Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:273.08Ref: TM-T1965
1mL*10mM (DMSO)33.00€10mg44.00€25mg73.00€50mg113.00€100mg177.00€200mg264.00€500mg447.00€GSK2334470
CAS:GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.Formula:C25H34N8OPurity:99.57% - 99.87%Color and Shape:SolidMolecular weight:462.59AG1557
CAS:AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).Formula:C16H14IN3O2Purity:98.61% - 99.23%Color and Shape:SolidMolecular weight:407.21Epitinib
CAS:Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).Formula:C24H26N6O2Color and Shape:SolidMolecular weight:430.5AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Formula:C21H23N7O3SPurity:98% - 99.25%Color and Shape:SolidMolecular weight:453.52PD153035 hydrochloride
CAS:PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.Formula:C16H15BrClN3O2Purity:99.39% - ≥95%Color and Shape:White SolidMolecular weight:396.67FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purity:97.63% - 98.92%Color and Shape:SolidMolecular weight:691.61LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:White SolidMolecular weight:307.34Parsaclisib hydrochloride
CAS:Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity.Formula:C20H23Cl2FN6O2Purity:98%Color and Shape:SolidMolecular weight:469.34Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:468.47Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formula:C30H35N7O2Purity:99.99%Color and Shape:White SolidMolecular weight:525.64Ref: TM-T5462
1mg94.00€5mg187.00€1mL*10mM (DMSO)235.00€10mg295.00€25mg497.00€50mg717.00€100mg982.00€500mg1,998.00€
