ATM/ATR
ATM (Ataxia Telangiectasia Mutated) and ATR (ATM and Rad3-related) are key kinases involved in the DNA damage response (DDR) that are activated in response to DNA double-strand breaks and replication stress. ATM/ATR inhibitors target these kinases, disrupting their ability to detect and repair DNA damage. This inhibition can lead to increased genomic instability and cell death, particularly in cancer cells that rely on robust DNA repair mechanisms for survival. ATM/ATR inhibitors are crucial tools in cancer research and therapy, especially in combination with DNA-damaging agents. At CymitQuimica, we provide a wide range of high-quality ATM/ATR inhibitors to support your research in DNA damage response, cancer biology, and therapeutic development.
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Elimusertib hydrochloride(1876467-74-1 free base)
Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor …
Formula:
C20H22ClN7O
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
411.89
Ref: TM-T10468
| 1mg | 36.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 340.00 € | ||
| 100mg | 483.00 € | ||
| 200mg | 664.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
A011
A011, a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor, exhibits an IC50 of 1.0 nM …
Formula:
C27H28N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
452.55
Ref: TM-T78711
| 1mg | 141.00 € | ||
| 5mg | 634.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Berzosertib
CAS:1232416-25-9
Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM). …
Formula:
C24H25N5O3S
Purity:
100% - 99.7%
Color and Shape:
Solid
Molecular weight:
463.55
Ref: TM-T2669
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 351.00 € | ||
| 200mg | 513.00 € | ||
| 500mg | 814.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Garcinone C
CAS:76996-27-5
Garcinone C, a xanthone from Garcinia oblongifolia, is anti-inflammatory, promotes healing, and may fight some …
Formula:
C23H26O7
Purity:
98.93%
Color and Shape:
Solid
Molecular weight:
414.45
Ref: TM-TN1673
| 1mg | 45.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ATM Inhibitor-9
ATM Inhibitor-9 (Compd 7a) is a potent inhibitor of ATM kinase, exhibiting an IC50 value …
Formula:
C25H32N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
448.56
Ref: TM-T79306
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ATM Inhibitor-8
ATM Inhibitor-8 (Compound 10r) is a potent, selective, and orally active inhibitor of ATM, exhibiting …
Formula:
C26H34N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
462.59
Ref: TM-T79305
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AZ20
CAS:1233339-22-4
AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a …
Formula:
C21H24N4O3S
Purity:
100.00% - 98.02%
Color and Shape:
Solid
Molecular weight:
412.51
Ref: TM-T1958
| 2mg | 39.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 249.00 € | ||
| 100mg | 369.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
NU6027
CAS:220036-08-8
NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 …
Formula:
C11H17N5O2
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
251.29
Ref: TM-T6612
| 5mg | 43.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 271.00 € | ||
| 200mg | 391.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
PIK-93
CAS:593960-11-3
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα …
Formula:
C14H16ClN3O4S2
Purity:
97.72%
Color and Shape:
Solid
Molecular weight:
389.88
Ref: TM-T2616
| 1mg | 44.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
AZD-7648
CAS:2230820-11-6
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM …
Formula:
C18H20N8O2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
380.4
Ref: TM-T7122
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
CGK733
CAS:905973-89-9
CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.
Formula:
C23H18Cl3FN4O3S
Purity:
98% - 99.7%
Color and Shape:
Solid
Molecular weight:
555.84
Ref: TM-T1821
| 5mg | 35.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 333.00 € | ||
| 500mg | 782.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Wortmannin
CAS:19545-26-7
Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.
Formula:
C23H24O8
Purity:
95.84% - 99.76%
Color and Shape:
White Solid
Molecular weight:
428.43
Ref: TM-T6283
| 1mg | 38.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
KU60019
CAS:925701-49-1
Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much …
Formula:
C30H33N3O5S
Purity:
95.9% - 99%
Color and Shape:
Solid
Molecular weight:
547.67
Ref: TM-T2474
| 1mg | 52.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 148.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 411.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
VE-821
CAS:1232410-49-9
VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM …
Formula:
C18H16N4O3S
Purity:
99.26% - 99.97%
Color and Shape:
Solid
Molecular weight:
368.41
Ref: TM-T3032
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
AZ32
CAS:2288709-96-4
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 …
Formula:
C20H16N4O
Purity:
99.68% - 99.94%
Color and Shape:
Solid
Molecular weight:
328.37
Ref: TM-T4443
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 326.00 € | ||
| 50mg | 509.00 € | ||
| 100mg | 727.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
GJ103 sodium salt
CAS:1459687-96-7
GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, …
Formula:
C16H13N4NaO3S
Purity:
99.63% - 99.88%
Color and Shape:
Solid
Molecular weight:
364.36
Ref: TM-T4251
| 2mg | 49.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 415.00 € | ||
| 100mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Ceralasertib
CAS:1352226-88-0
Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib …
Formula:
C20H24N6O2S
Purity:
98% - 99.99%
Color and Shape:
Solid
Molecular weight:
412.51
Ref: TM-T3338
| 1mg | 50.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 143.00 € | ||
| 50mg | 408.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Schisandrin B
CAS:61281-37-6
Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.
Formula:
C23H28O6
Purity:
100% - 99.84%
Color and Shape:
Solid
Molecular weight:
400.46
Ref: TM-T2925
| 1mg | 41.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 405.00 € | ||
| 100mg | 587.00 € | ||
| 500mg | 1,233.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
AZD0156
CAS:1821428-35-6
AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and …
Formula:
C26H31N5O3
Purity:
99.03% - 99.13%
Color and Shape:
Solid
Molecular weight:
461.56
Ref: TM-T6770
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,068.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
CP-466722
CAS:1080622-86-1
CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK …
Formula:
C17H15N7O2
Purity:
99.14% - 99.85%
Color and Shape:
Solid
Molecular weight:
349.35
Ref: TM-T6261
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 475.00 € | ||
| 500mg | 1,049.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
