ATM/ATR
ATM (Ataxia Telangiectasia Mutated) and ATR (ATM and Rad3-related) are key kinases involved in the DNA damage response (DDR) that are activated in response to DNA double-strand breaks and replication stress. ATM/ATR inhibitors target these kinases, disrupting their ability to detect and repair DNA damage. This inhibition can lead to increased genomic instability and cell death, particularly in cancer cells that rely on robust DNA repair mechanisms for survival. ATM/ATR inhibitors are crucial tools in cancer research and therapy, especially in combination with DNA-damaging agents. At CymitQuimica, we provide a wide range of high-quality ATM/ATR inhibitors to support your research in DNA damage response, cancer biology, and therapeutic development.
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KU-55933
CAS:587871-26-9
KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has …
Formula:
C21H17NO3S2
Purity:
100% - 99.80%
Color and Shape:
Solid
Molecular weight:
395.49
Ref: TM-T2685
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 100.00 € | ||
| 50mg | 160.00 € | ||
| 100mg | 269.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
AZ20
CAS:1233339-22-4
AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a …
Formula:
C21H24N4O3S
Purity:
100.00% - 98.02%
Color and Shape:
Solid
Molecular weight:
412.51
Ref: TM-T1958
| 2mg | 39.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 249.00 € | ||
| 100mg | 369.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
Elimusertib
CAS:1876467-74-1
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 …
Formula:
C20H21N7O
Purity:
98.95% - 99.75%
Color and Shape:
Solid
Molecular weight:
375.43
Ref: TM-T7318
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 551.00 € | ||
| 500mg | 1,179.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
Dactolisib
CAS:915019-65-7
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 …
Formula:
C30H23N5O
Purity:
97.64% - 99.85%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T2235
| 25mg | 46.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 69.00 € | ||
| 200mg | 104.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
(Z)-Mirin
CAS:1198097-97-0
(Z)-Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
Formula:
C10H8N2O2S
Purity:
98.37% - 99.96%
Color and Shape:
Solid
Molecular weight:
220.25
Ref: TM-T3134
| 5mg | 54.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 407.00 € | ||
| 200mg | 531.00 € | ||
| 500mg | 852.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
azd1390
CAS:2089288-03-7
AZD1390: Potent ATM inhibitor (IC50: 0.78 nM), >10,000-fold selectivity vs. PIKK enzymes.
Formula:
C27H32FN5O2
Purity:
97.47% - 99.38%
Color and Shape:
Solid
Molecular weight:
477.57
Ref: TM-T5175
| 1mg | 86.00 € | ||
| 2mg | 105.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 224.00 € | ||
| 25mg | 453.00 € | ||
| 50mg | 578.00 € | ||
| 100mg | 745.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
ETP-46464
CAS:1345675-02-6
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
Formula:
C30H22N4O2
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
470.52
Ref: TM-T2084
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 430.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
ATR-IN-23
CAS:2923800-62-6
ATR-IN-23 (Compound 34), a potent and selective ATR inhibitor, exhibits an IC50 of 1.5 nM, …
Formula:
C20H22N6O3S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
458.56
Ref: TM-T78959
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
Gartisertib
CAS:1613191-99-3
Gartisertib (VX-803) is an ATR inhibitor with anti-tumor activity, inhibiting the anti-proliferative effects induced in …
Formula:
C25H29F2N9O3
Color and Shape:
Solid
Molecular weight:
541.55
Ref: TM-T10407
| 1mg | 138.00 € | ||
| 5mg | 332.00 € | ||
| 10mg | 555.00 € | ||
| 25mg | 1,109.00 € | ||
| 50mg | 1,470.00 € | ||
| 100mg | 2,209.00 € | ||
| 1mL*10mM (DMSO) | 396.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
AZ31
CAS:2088113-98-6
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, …
Formula:
C24H28N4O3
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
420.5
Ref: TM-T19671
| 1mg | 52.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 165.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 579.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Lartesertib
CAS:2495096-26-7
Lartesertib (ATM Inhibitor-5) is an inhibitor of the serine/threonine protein kinase ATM with potential anticancer …
Formula:
C23H21FN6O3
Purity:
99.9%
Color and Shape:
Liquid
Molecular weight:
448.45
Ref: TM-T62684
| 1mg | 128.00 € | ||
| 2mg | 183.00 € | ||
| 5mg | 306.00 € | ||
| 10mg | 524.00 € | ||
| 25mg | 1,016.00 € | ||
| 50mg | 1,696.00 € | ||
| 100mg | 2,627.00 € | ||
| 1mL*10mM (DMSO) | 342.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
ATR-IN-21
CAS:2905312-17-4
ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 …
Formula:
C23H27N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
417.51
Ref: TM-T79031
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
ATR-IN-29
CAS:2761193-67-1
ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM …
Formula:
C19H22N8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
378.43
Ref: TM-T79121
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
ATR-IN-22
CAS:2905312-07-2
ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells …
Formula:
C25H31N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
445.56
Ref: TM-T79033
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
ATR-IN-24
CAS:2370889-43-1
ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].
Formula:
C23H26N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
418.49
Ref: TM-T79058
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Camonsertib
CAS:2417489-10-0
Camonsertib (RP-3500) is a novel, potent and selective ATR kinase inhibitor (ATRi) that exhibits potent …
Formula:
C21H26N6O3
Purity:
98.15% - 99.6%
Color and Shape:
Liquid
Molecular weight:
410.47
Ref: TM-T62083
| 1mg | 166.00 € | ||
| 5mg | 407.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,225.00 € | ||
| 100mg | 1,689.00 € | ||
| 1mL*10mM (DMSO) | 460.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
KU 59403
CAS:845932-30-1
KU 59403 is an effective ATM inhibitor (IC50: 3 nM, 9.1 μM, and 10 μM …
Formula:
C29H32N4O4S2
Purity:
99.10%
Color and Shape:
Solid
Molecular weight:
564.72
Ref: TM-T15673
| 25mg | 818.00 € | ||
| 50mg | 1,090.00 € | ||
| 100mg | 1,649.00 € |
Estimated delivery in United States, on Wednesday 14 May 2025
KU-60019
CAS:925701-46-8
KU-60019 is a specific inhibitor of ATM kinase (IC50: 6.3 nM).
Formula:
C30H33N3O5S
Purity:
97.15%
Color and Shape:
Liquid
Molecular weight:
547.67
Ref: TM-T63872
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 511.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 14 May 2025
ATM Inhibitor-1
CAS:2135639-94-8
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) …
Formula:
C27H36N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
492.61
Ref: TM-T10396
| 25mg | 2,245.00 € | ||
| 50mg | 2,963.00 € | ||
| 100mg | 4,006.00 € |
Estimated delivery in United States, on Wednesday 14 May 2025
