mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Found 164 products for "mTOR".
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XL388
CAS:XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.Formula:C23H22FN3O4SPurity:99.39% - 99.53%Color and Shape:SolidMolecular weight:455.5GNE-493
CAS:GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM forFormula:C17H20N6O2SPurity:98%Color and Shape:SolidMolecular weight:372.44Cyclovirobuxine D
CAS:Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formula:C26H46N2OPurity:97.78% - 98%Color and Shape:SolidMolecular weight:402.66OSI-027
CAS:OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formula:C21H22N6O3Purity:97.42%Color and Shape:SolidMolecular weight:406.44Ref: TM-T6319
1mg39.00€2mg50.00€5mg81.00€1mL*10mM (DMSO)84.00€10mg131.00€25mg235.00€50mg369.00€100mg537.00€PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48Ref: TM-T6251
1mg34.00€2mg43.00€5mg63.00€1mL*10mM (DMSO)65.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48D-α-Hydroxyglutaric acid disodium
CAS:D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.Formula:C5H6Na2O5Purity:97.16%Color and Shape:SolidMolecular weight:192.083BDO
CAS:3BDO is a new mTOR activator. 3BDO inhibits autophagy.Formula:C18H17NO5Purity:97.76%Color and Shape:SolidMolecular weight:327.33Ref: TM-T14033
1mg34.00€2mg44.00€5mg64.00€1mL*10mM (DMSO)71.00€10mg92.00€25mg195.00€50mg313.00€100mg467.00€GDC0084
CAS:GDC0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity.Formula:C18H22N8O2Purity:99.26% - 99.87%Color and Shape:White SolidMolecular weight:382.42GNE-477
CAS:GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.Formula:C21H28N8O3S2Purity:98.88% - 99.55%Color and Shape:SolidMolecular weight:504.63Ref: TM-T3692
1mg44.00€2mg57.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg138.00€25mg286.00€50mg447.00€100mg677.00€Salidroside
CAS:Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Formula:C14H20O7Purity:97.81% - 99.89%Color and Shape:Yellow SolidMolecular weight:300.30Ref: TM-T2717
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg81.00€25mg130.00€50mg178.00€100mg268.00€200mg408.00€Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purity:99.93% - 99.98%Color and Shape:Red SolidMolecular weight:384.47Mito-LND
CAS:Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formula:C43H45BrCl2N3OPPurity:97.25% - 98.34%Color and Shape:SolidMolecular weight:801.62GNE-317
CAS:GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).Formula:C19H22N6O3SPurity:98.42% - 99.54%Color and Shape:White SolidMolecular weight:414.48Ref: TM-T6845
2mg43.00€5mg63.00€1mL*10mM (DMSO)70.00€10mg92.00€25mg192.00€50mg264.00€100mg339.00€200mg497.00€Everolimus
CAS:Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.Formula:C53H83NO14Purity:97.76% - 99.78%Color and Shape:SolidMolecular weight:958.22Ref: TM-T1784
5mg42.00€10mg52.00€1mL*10mM (DMSO)52.00€25mg78.00€50mg90.00€100mg114.00€200mg168.00€500mg281.00€25(R,S)-Ruscogenin
CAS:25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular carcinoma.Formula:C27H42O4Purity:99.32% - 99.89%Color and Shape:White SolidMolecular weight:430.62AZD-8055
CAS:AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.Formula:C25H31N5O4Purity:98% - 99.69%Color and Shape:SolidMolecular weight:465.54NV-5138 hydrochloride
NV-5138 hydrochloride: a leucine analog, oral brain mTORC1 activator via Sestrin2, for antidepressant research.Formula:C7H14ClF2NO2Color and Shape:SolidMolecular weight:217.64Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formula:C24H22O6Purity:98.40% - 98.59%Color and Shape:SolidMolecular weight:406.43KU-0063794
CAS:KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.Formula:C25H31N5O4Purity:98.21% - >99.99%Color and Shape:White SolidMolecular weight:465.54WYE-687 dihydrochloride
CAS:WYE-687 dihydrochloride is an mTOR inhibitor with IC50 of 7 nM, also targeting PI3Kα (81 nM) and PI3Kγ (3.11 μM).Formula:C28H34Cl2N8O3Color and Shape:SolidMolecular weight:601.53SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:Yellow SolidMolecular weight:336.15L-Leucine
CAS:L-Leucine is an essential amino acid vital for protein synthesis, metabolism, muscle and bone repair, blood sugar control, and wound healing.Formula:C6H13NO2Purity:98.76% - 99.83%Color and Shape:White SolidMolecular weight:131.17Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54Ref: TM-T1961
1mg34.00€5mg71.00€1mL*10mM (DMSO)79.00€10mg111.00€25mg170.00€50mg225.00€100mg358.00€200mg530.00€Onatasertib
CAS:Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formula:C21H27N5O3Purity:99.14% - 99.93%Color and Shape:Purple SolidMolecular weight:397.47Voxtalisib
CAS:Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.Formula:C13H14N6OPurity:98.21% - 99.69%Color and Shape:SolidMolecular weight:270.29Ref: TM-T7014
1mg35.00€2mg50.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg117.00€25mg226.00€50mg364.00€100mg532.00€mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formula:C16H15BrN2O3Purity:99.43%Color and Shape:White SolidMolecular weight:363.21Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purity:98% - 99.36%Color and Shape:SolidMolecular weight:855.02Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formula:C35H28F3N5O2Purity:98.3% - 99.33%Color and Shape:White SolidMolecular weight:607.62G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:Yellow SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€Apitolisib
CAS:Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).Formula:C23H30N8O3SPurity:98.28% - 99.64%Color and Shape:SolidMolecular weight:498.6Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.95%Color and Shape:SolidMolecular weight:178.14GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Formula:C18H11N3O2SPurity:99.3% - ≥95%Color and Shape:White SolidMolecular weight:333.36Serabelisib
CAS:Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).Formula:C19H17N5O3Purity:98.41% - 99.5%Color and Shape:SolidMolecular weight:363.37LY 303511 hydrochloride
CAS:LY 303511 hydrochloride is a potent mTOR inhibitorFormula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82Sapanisertib
CAS:Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formula:C15H15N7OPurity:99.19% - >99.99%Color and Shape:SolidMolecular weight:309.33Ref: TM-T1838
1mg38.00€2mg49.00€5mg80.00€1mL*10mM (DMSO)84.00€10mg90.00€25mg152.00€50mg222.00€100mg333.00€500mg795.00€LY-2584702 free base
CAS:LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).Formula:C21H19F4N7Purity:98.72% - 99.51%Color and Shape:SolidMolecular weight:445.42Ref: TM-T6159
1mg44.00€2mg56.00€5mg108.00€10mg140.00€25mg299.00€50mg404.00€100mg592.00€500mg1,243.00€Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purity:98.76% - 99.92%Color and Shape:SolidMolecular weight:897.1Ref: TM-T2P2806
1mg46.00€5mg114.00€1mL*10mM (DMSO)161.00€10mg167.00€25mg268.00€50mg408.00€100mg587.00€200mg825.00€Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purity:96.66% - 99.93%Color and Shape:White SolidMolecular weight:332.39CDC25B-IN-2
CAS:BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.Formula:C15H12N2O3Purity:99.12%Color and Shape:SolidMolecular weight:268.27CH5132799
CAS:CH5132799 has been used in trials studying the treatment of Solid Tumors.Formula:C15H19N7O3SPurity:99.41% - 99.87%Color and Shape:SolidMolecular weight:377.42Ref: TM-T2619
1mg60.00€2mg92.00€5mg137.00€10mg215.00€25mg399.00€50mg590.00€100mg838.00€500mg1,693.00€GSK-25
CAS:GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Formula:C24H16Cl2F2N6OPurity:99.29%Color and Shape:SolidMolecular weight:513.33Ref: TM-T4488
1mg44.00€2mg56.00€5mg87.00€1mL*10mM (DMSO)89.00€10mg111.00€25mg168.00€50mg258.00€100mg430.00€Torkinib
CAS:Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).Formula:C16H16N6OPurity:99.11%Color and Shape:White SolidMolecular weight:308.34Ref: TM-T2414
5mg54.00€1mL*10mM (DMSO)59.00€10mg71.00€25mg90.00€50mg129.00€100mg215.00€200mg319.00€500mg530.00€Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White SolidMolecular weight:1030.29Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Formula:C30H48O5Purity:96.91% - 99.97%Color and Shape:White SolidMolecular weight:488.70Ref: TM-T5S0506
2mg34.00€5mg49.00€1mL*10mM (DMSO)49.00€10mg75.00€25mg137.00€50mg215.00€100mg319.00€200mg474.00€TMBIM6 antagonist-1
CAS:TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitorFormula:C15H12N2O3Purity:99.26%Color and Shape:SolidMolecular weight:268.27Ref: TM-T8649
1mg88.00€2mg114.00€5mg177.00€1mL*10mM (DMSO)190.00€10mg299.00€25mg537.00€50mg767.00€100mg1,054.00€500mg2,115.00€(+)-Usnic acid
CAS:(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.Formula:C18H16O7Purity:98.22%Color and Shape:SolidMolecular weight:344.32CZ415
CAS:CZ415 is a potent and highly selective mTOR inhibitor.Formula:C22H29N5O4SPurity:97.54% - 98.36%Color and Shape:SolidMolecular weight:459.56Ref: TM-T3514
1mg39.00€2mg49.00€5mg71.00€1mL*10mM (DMSO)72.00€10mg104.00€25mg212.00€50mg319.00€100mg447.00€200mg618.00€VS-5584
CAS:VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.Formula:C17H22N8OPurity:97.82% - 99.54%Color and Shape:White SolidMolecular weight:354.41Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purity:96.68% - 98.22%Color and Shape:SolidMolecular weight:320.25
