mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
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Samotolisib
CAS:1386874-06-1
Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.
Formula:
C23H26N4O3
Purity:
98.41% - 99.69%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T6883
| 5mg | 48.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 368.00 € | ||
| 200mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
D-α-Hydroxyglutaric acid disodium
CAS:103404-90-6
D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of …
Formula:
C5H6Na2O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
192.08
Ref: TM-T6820
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 272.00 € | ||
| 500mg | 458.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
3BDO
CAS:890405-51-3
3BDO is a new mTOR activator. 3BDO inhibits autophagy.
Formula:
C18H17NO5
Purity:
96.00%
Color and Shape:
Solid
Molecular weight:
327.33
Ref: TM-T14033
| 2mg | 46.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 508.00 € | ||
| 200mg | 759.00 € | ||
| 500mg | 1,166.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CZ415
CAS:1429639-50-8
CZ415 is a potent and highly selective mTOR inhibitor.
Formula:
C22H29N5O4S
Purity:
98.36% - 98.44%
Color and Shape:
Solid
Molecular weight:
459.56
Ref: TM-T3514
| 1mg | 41.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 454.00 € | ||
| 200mg | 629.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
VS-5584
CAS:1246560-33-7
VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.
Formula:
C17H22N8O
Purity:
97.82% - 99.54%
Color and Shape:
Solid
Molecular weight:
354.41
Ref: TM-T6103
| 5mg | 37.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 135.00 € | ||
| 100mg | 186.00 € | ||
| 200mg | 279.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Dihydromyricetin
CAS:27200-12-0
Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and …
Formula:
C15H12O8
Purity:
96.68% - 98.13%
Color and Shape:
Solid
Molecular weight:
320.25
Ref: TM-T2998
| 5mg | 46.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 134.00 € | ||
| 500mg | 324.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MHY1485
CAS:326914-06-1
MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby …
Formula:
C17H21N7O4
Purity:
100% - 98%
Color and Shape:
Solid
Molecular weight:
387.39
Ref: TM-T1908
| 5mg | 55.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 342.00 € | ||
| 200mg | 502.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ETP-45658
CAS:1198357-79-7
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 …
Formula:
C16H17N5O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T25399
| 1mg | 52.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Dactolisib
CAS:915019-65-7
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 …
Formula:
C30H23N5O
Purity:
97.64% - 99.85%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T2235
| 25mg | 46.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 69.00 € | ||
| 200mg | 104.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PQR620
CAS:1927857-56-4
PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.
Formula:
C21H25F2N7O2
Purity:
97.61%
Color and Shape:
Solid
Molecular weight:
445.47
Ref: TM-T5472
| 1mg | 62.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 342.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 653.00 € | ||
| 200mg | 881.00 € | ||
| 1mL*10mM (DMSO) | 141.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DMH-25
CAS:1685280-21-0
DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor …
Formula:
C15H8Br3NO3
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
489.94
Ref: TM-T8569
| 1mg | 84.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 248.00 € | ||
| 25mg | 408.00 € | ||
| 50mg | 574.00 € | ||
| 100mg | 776.00 € | ||
| 200mg | 1,029.00 € | ||
| 1mL*10mM (DMSO) | 203.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ridaforolimus
CAS:572924-54-0
Ridaforolimus (AP23573), a rapamycin analogue, inhibits mTOR to potentially arrest tumor growth/proliferation via PI3K/Akt pathway.
Formula:
C53H84NO14P
Purity:
90.00% - 98.55%
Color and Shape:
Off-White Solid
Molecular weight:
990.21
Ref: TM-T6334
| 5mg | 55.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 278.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DIM-C-pPhOH
CAS:151358-47-3
CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 …
Formula:
C23H18N2O
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
338.4
Ref: TM-T4400
| 2mg | 44.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 368.00 € | ||
| 200mg | 486.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
mTOR inhibitor-1
CAS:468747-17-3
C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.
Formula:
C16H15BrN2O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
363.21
Ref: TM-T5338
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 458.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PQR530
CAS:1927857-61-1
PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and …
Formula:
C18H23F2N7O2
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
407.42
Ref: TM-T16567
| 1mg | 34.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PKCβ inhibitor 1
CAS:257879-35-9
PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of …
Formula:
C24H21N5O2
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
411.46
Ref: TM-T8376
| 1mg | 153.00 € | ||
| 5mg | 421.00 € | ||
| 10mg | 601.00 € | ||
| 25mg | 914.00 € | ||
| 50mg | 1,188.00 € | ||
| 100mg | 1,633.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KU-0060648
CAS:881375-00-4
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 …
Formula:
C33H34N4O4S
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
582.71
Ref: TM-T6557
| 1mg | 58.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 441.00 € | ||
| 100mg | 631.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Desmethyl-VS-5584
CAS:1246535-95-4
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR …
Formula:
C16H20N8O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T4199
| 1mg | 58.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 148.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 421.00 € | ||
| 50mg | 620.00 € | ||
| 100mg | 884.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MHY-1685
CAS:27406-31-1
MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can …
Formula:
C11H8N2O4
Purity:
98.44%
Color and Shape:
Solid
Molecular weight:
232.19
Ref: TM-T40351
| 25mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DS-7423
CAS:1222104-37-1
DS-7423: a dual PI3K/mTOR inhibitor; IC50s-PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: …
Formula:
C22H27F3N10O2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
520.51
Ref: TM-T36083
| 1mg | 127.00 € | ||
| 5mg | 283.00 € | ||
| 10mg | 433.00 € | ||
| 25mg | 708.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,378.00 € | ||
| 1mL*10mM (DMSO) | 322.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
