Oligosaccharides

Gangliotetraose (Galβ1,3GalNAcβ1,4Galβ1,4Glc) is the core tetrasaccharide found in many gangliosides, such as, GM1 (Ledeen, 2009). Gangliosides containing gangliotetraose are abundant in mammalian brains, where they can cover 10%–20% of the total ganglioside mixture. They are found in epithelial membranes and are key elements for bacterial toxicity and viral infection, for example, it is the intestinal receptor for cholera toxin, the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. They can function as neurotrophic and neuroprotective compounds, and have been used therapeutically for diabetic and peripheral neuropathies. They bind amyloid-β proteins and are involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).

Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant

Melezitose is a non-reducing trisaccharide that is produced by many plant sap-consuming insects, such as aphids (e.g. Cinara pilicornis).  Melezitose is a component of honeydew which acts as an attractant for ants and also as food for bees. Partial hydrolysis of melizitose releases glucose and turanose, an isomer of sucrose.

Neutral pentasaccharide naturally present in human breast milk

A2F N-Glycan is an oligosaccharide that is found in the human body. It is a glycan that has been shown to be involved in a number of biological processes, including effector functions, site specific recognition, diagnosis, and biopharmaceutical production. A2F N-glycan has also been shown to have potential as a biomarker for autoimmune diseases and cancer. The A2F N-glycan profile may differ between patients with different cancers or autoimmune disorders. This difference in the A2F N-glycan profile may contribute to the development of personalized medicine by helping to diagnose these conditions and predict their prognosis.

Produced from high maltose syrup by treatment with transglucosidase

The chemical name of the compound is 4-Methoxyphenyl 2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-a-D-glucopyranosyl)-3,4-di-O-benzyl--6--O--pivaloyl-[a]-D--mannopyranoside. The molecular formula is C47H69NO17. The molecular weight is 838.10 g/mol. This product is a white to off white solid that has no odor and a sweet taste. Compound can be custom synthesized to customer's specification and purity requirements. The CAS number for this compound is 1820574-70-6.

Raffinose is the most abundant of the family of oligosaccharides that are alpha-galactosyl derivatives of sucrose (Collins, 2006). The other main member of the group is the tetrasaccharide stachyose. Raffinose is found in sugar beet molasses and whole grains. Soybean oligosaccharides make up approximately 5% of dry matter in whole beans and up to 8% of dry matter in soybean meal. Together raffinose and stachyose rank second only to sucrose in abundance, as water-soluble carbohydrates (Kumar, 2010).

Blood group antigen derivative for biochemical research

6-Sialylgalacto-N-biosyl-serine is a custom synthesis product that has been fluorinated and modified. The material is an Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate with a CAS number of 60919-07-2. It is highly pure with a purity of > 98% by HPLC analysis. The modification on the sugar molecule includes Click chemistry and Methylation. The monosaccharide sugar is the saccharide part of the molecule.

Manninotriose is a mannose-containing oligosaccharide that has been found to have high resistance against enzymes. This mannose-containing oligosaccharide can be used as a biomarker for the detection of activated macrophages in biological samples, such as serum and urine. It is also used as an activator of monoclonal antibodies, which are used in the diagnosis of autoimmune diseases. Manninotriose may act as a signal peptide for the activation of enzyme activities, such as glycosyl transferase reactions and caffeic acid hydrolase.

4-Methoxyphenyl 2-acetamido-3,6-di-O-acetyl-4-O-[2,4-di-O-(3,6,9)-triacetyldi-O-(3,4,6)-triacetyldiacetamido]-bDglucopyranoside (MPPA) is a modification of the natural oligosaccharide 3,6,-di-O-(2,4-di-O-(3,6,9)-triacetyldiacyl)-bDmannopyranosyl. MPPA is synthesized by methylation and glycosylation of glucose residues in the backbone of the natural oligosaccharide. The methylated glycosidic linkages are substituted for acetamido groups in order to confer water solubility to the molecule. MPPA has been shown to be an effective inhibitor of influenza virus replication in vitro.

Chitoheptaose 7HCl is a synthetic, complex carbohydrate with a CAS number of 68232-35-9. This product is custom synthesized to order and can be modified according to your specifications. It is available in high purity.

Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. It also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods and may be used as an ingredient in culture media.