Oligosaccharides

<p>2-Acetamido-2-deoxy-4-O-(a-L-fucopyranosyl)-D-glucopyranose is a methylated, custom synthesized oligosaccharide. It has been modified to include a fluorine atom at the C4 position on the glucose residue. The product is highly pure and in crystalline form, with a CAS number of 76211-71-7.</p>

<p>Core human milk oligosaccharide</p>

<p>Chitobiose is a dimer formed by beta-1,4-linked glucosamine units.<br>It is also the repeated dimer of chitin, a polysaccharide.</p>

<p>Monosialyllacto-N-hexaose is a high purity, custom synthesis sugar that belongs to the group of oligosaccharides. This carbohydrate is modified with fluorination and glycosylation, which are Click modifications. Monosialyllacto-N-hexaose has a CAS number of 68638-04-3. This product is available for purchase in bulk quantities.</p>

<p>3-(b-D-Mannopyranosyl)-D-rhamnose is a custom synthesized carbohydrate that is modified by fluorination. It is also a complex carbohydrate with an Oligosaccharide, sugar, and a Monosaccharide. 3-(b-D-Mannopyranosyl)-D-rhamnose has high purity and can be used for methylation, glycosylation, or Click modifications. Click modification is an organic chemistry technique that uses a copper ion to add chemical groups to the surface of molecules. This provides access to new functionalities, such as increased solubility or stability in organic solvents.</p>

<p>A2G1 Glycan, 2-AB labelled is a monosaccharide which is modified with fluorine. A2G1 Glycan, 2-AB labelled is used in the synthesis of complex carbohydrate structures. It has been shown to be useful for click modification, methylation and polysaccharide synthesis. This compound can also be custom synthesized to order. The purity of this product is high and it is available in a range of CAS numbers.</p>

<p>Component of glycoproteins and glycolipids expressed in antigens and receptors of proteins, bacteria and viruses. Found in the free form in human biofluids, including urine and milk - preventing adhesion of bacteria to urinary epithelium and inhibiting enteric pathogens respectively. An efficient inhibitor of neutrophil-activating protein of H.pylori (HPNAP)-mediated neutrophil activation.</p>

<p>NGA4 Glycan, 2-AB labelled is a synthetic oligosaccharide that has been modified with Click chemistry. This modification has been shown to be useful for the detection of methylation. The NGA4 Glycan, 2-AB labelled has a purity of &gt;99% and is available in quantities of 1 mg or more.</p>

<p>N-Acetylneuraminic acid (NA2) is a glycan that is found in the human body, and is important for brain function. NA2 Glycan, 2-AB labelled, is a high purity custom synthesis sugar with Click modification and fluorination. The glycans are made of monosaccharides or saccharides linked together by glycosidic bonds. Carbohydrates are classified according to their number of sugar units: simple carbohydrates contain one or two sugar units; complex carbohydrates have three or more. This product is an oligosaccharide that contains nine sugar units: three monosaccharides and six saccharides. It can be used as a substrate for methylation, glycosylation, and modification reactions.</p>

<p>Chitotriose trihydrochloride is a modification of chitin, an oligosaccharide. Chitotriose trihydrochloride is a synthetic carbohydrate which is used as a raw material for the production of fibers, films, and adhesives. It can be used in the synthesis of complex carbohydrates such as starch and glycogen. Chitotriose trihydrochloride is a high purity carbohydrate with CAS No. 41708-93-4 that can be used to produce glycosylated proteins or polysaccharides.</p>

<p>Kojipentaose is a glycosidic oligosaccharide that is synthesized by the enzyme phosphorylase. It is an important nutrient for many organisms, including bacteria and fungi. Kojipentaose has been found to be synthesized from the terminal sugars of teichoic acids in both Gram-positive and Gram-negative bacteria. The stereoselectivity of the synthesis may be due to enzymatic activity or the availability of chiral substrates.</p>

<p>2-Acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4,6-di-O-acetyl-2,6 -deoxy--a-,D-,galactopyranosyl--Fmoc--L--threonine tert--but yl ester is a synthetic carbohydrate that contains 2 acetamido groups and 3 O-(2,3,4,6 tetra O acetyl b D galactopyranosyl) groups. The chemical name for this compound is 2 Acetamido 3 O (2 3 4 6 tetra O acetyl b D galactopyranosyl) 4 6 di O acetyl 2 deoxy a D galactopyranosyl Fmoc L threonine tert but yl ester. It has been synthesized by the Click modification reaction of an oligos</p>

<p>Gala1-3Galb1-4GlcNAc-O-L-serine is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. The CAS number for this product is . It has been created by the process of Glycosylation. This product is a Carbohydrate and a Polysaccharide. The molecular weight of this product is .</p>

<p>4-Methoxyphenyl 4-O-[2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-(3,4,6,-tri -O acetyl 2 deoxy 2 phthalimido b D glucopyranosyl) b D mannopyranosyl] 3,6 di O benzyl 2 deoxy 2 phthalimido b D glucopyranoside (MPP) is a carbohydrate that belongs to the group of saccharides. It is an oligosaccharide sugar with a molecular weight of 1029.5 Da. This compound has been custom synthesized and is available in high purity. MPP is an ester of 4 methoxyphenol and 4 O-[2 O-(3,4,6 tri O acetyl 2 deoxy</p>

<p>Isomalto oligomers are a custom synthesis of polysaccharide oligosaccharides. These compounds are modified with methylation, glycosylation, and fluorination to create a high purity product that is free of undesirable contaminants. Isomalto oligomers (DP 4-8) are synthesized from sugars and can be used in the modification of saccharide chains during glycosylation reactions. This product also has the ability to produce click chemistry modifications.</p>

<p>Benzyl 4-O-b-D-galactopyranosyl-b-D-xylopyranoside is a glycoside that is used in the synthesis of antibiotics. It can be found in the leaves of "Ajania cordata" and "Chenopodium ambrosioides".</p>

<p>k-carrageenan derived disaccharide alcohol sulfate</p>

<p>Maltotriosyltrehalose is a sugar that is found in plants, fungi, and bacteria. It can be used as a substrate for the production of hydrogen-bonded oligosaccharides. Maltotriosyltrehalose has been shown to have a protective effect against death induced by high temperatures in mammalian cells. This sugar is also a good substrate for the production of hydrogen-bonded oligosaccharides and can be used as an additive to dry food products such as bread or cereals. Maltotriosyltrehalose is stable at high temperatures and has been shown to protect against cell death caused by heat stress. It can be used in both animal feed and human food products. Maltotriosyltrehalose is not active against proteases, but it does not inhibit the activity of mammalian cells that produce proteases.</p>

<p>Chitosan is the deacetylated form of chitin. The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid). This then allows the material to be used in a number of industrial applications as a binder and film former.Molecular weight range 350 - 3500 Da.</p>

<p>The acetates of lactose are useful starting points and intermediates in the synthesis of oligosaccharides based on lactose, particularly in the synthesis of the important oligosaccharides that occur in human milk.</p>

<p>Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.</p>

<p>A custom synthesis of a complex carbohydrate. It is a synthetic, modified and fluorinated saccharide with a methylated monosaccharide.</p>

<p>Lacto-N-neotetraose (LNnT) is a neutral and abundant human milk oligosaccharide (HMO), composed of four sugar molecules. It supports the infant's gut microbiota development and provides protection against infectious diseases. LNnT like many other HMOs offers great interest for the studies of baby milk formula.</p>

<p>Ganglioside GM1 has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue, ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009), and is abundant in all mammalian brains, where it covers 10%-20% of the total ganglioside mixture. Ganglioside GM1 is found in epithelial membranes and is a key element for the detection of bacterial toxicity and viral infection. It is the intestinal receptor for cholera toxin, the B-subunits of heat-labile toxin (LTB) from E.coli, for rotavirus, and simian virus 40. GM1 functions as a neurotrophic and neuroprotective compound and has been used therapeutically for diabetic and peripheral neuropathies. It also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>MurNAc-6-phosphate-GlcNAc is a complex carbohydrate that is composed of a glycosylation, methylation, and fluorination. It is an important component in polysaccharides and oligosaccharides. This compound has been modified with Click chemistry to form a reactive site for incorporation of a variety of molecules such as fluorophores, biotin, or other small molecules. This compound can be synthesized using custom synthesis methods and has CAS number 106579-01-4. MurNAc-6-phosphate-GlcNAc is available in high purity and can be custom synthesized to specific needs.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-a-D-galactopyranoside is a synthetic, fluorinated glycoside that is used as a building block for the synthesis of complex carbohydrates. Methyl 2-acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-a-D-galactopyranoside can be used in either Click or Fluorination reactions to synthesize oligosaccharides and monosaccharides. It has been shown to react with ethylene glycol to form methyl 2,6 -O-[(3,4,5,6 -tetra‑O‑acetyl‑β‑D‑galactopyranosyl)α -L‑idopyranosyl]-α -L‑idopyranose. Methyl 2,6 -</p>

<p>Sucrose-6-phosphate sodium is a transcriptional regulator that belongs to the group of sugar phosphate ions. Sucrose-6-phosphate sodium regulates the transcription of genes involved in the synthesis of polysaccharides, such as sucrose and starch. This compound plays an important role in the metabolism of plants and has been shown to regulate hydrogen bond formation, photosynthetic activity, glycosidic bond formation, polymerase chain reactions, and regulatory sequences. The optimum pH for this compound is 7.0, with enzyme activities between pH 6.0 and 8.5. Sucrose-6-phosphate sodium also has been shown to regulate root formation and phosphorus pentoxide production in corynebacterium glutamicum.</p>

<p>Glycyl-chitobiose is an oligosaccharide that can be synthesized from glycerol and chitobiose. This product is often used as a building block for the synthesis of complex carbohydrate molecules. The purity of Glycyl-chitobiose is greater than 98% and it has been modified with fluorine, methyl, and click chemistry. The CAS number for this product is 627-14-1.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Lewis B tetrasaccharide (LBT) is a glycosylated oligosaccharide that is found in the outer membrane of human pathogens, such as Helicobacter pylori. LBT has been shown to inhibit the growth of cancer cells and may be used as a potential therapeutic agent for cancer treatment. It has also been shown to have structural features similar to those found in inflammatory bowel disease patients, suggesting that it may play a role in regulating bowel inflammation. LBT is recognized by monoclonal antibodies and can be used to detect H. pylori in biological samples. Lewis B tetrasaccharide binds with methyl glycosides on human erythrocytes, which inhibits the polymerase chain reaction (PCR). This inhibition leads to reduced DNA synthesis and a decrease in bacterial replication, making it an effective antimicrobial agent.</p>

<p>2-O-(a-D-Galactopyranosyl)-D-glucopyranose is a disaccharide consisting of two monosaccharides, glucose and galactose. It also contains a hydroxy group on the second carbon atom in the molecule. 2-O-(a-D-Galactopyranosyl)-D-glucopyranose is found in some plants including sugarcane, sugar beet, and sweet potatoes. This disaccharide is broken down by enzymes called beta-galactosidases into its two monosaccharides. Beta-galactosidases are used as an enzyme therapy to treat certain genetic disorders that affect the breakdown of carbohydrates.</p>

<p>Lactitol is a polyol that is used as a sweetener and has the potential to cause diarrhea. It belongs to the group of sugar alcohols, which are not completely digested by humans. Lactitol is produced from lactose, which is derived from milk. The main clinical relevance of lactitol is its high intestinal permeability, low caloric value, and ability to lower blood glucose levels in diabetics. Lactitol undergoes microbial metabolism through the action of certain bacteria in the colon and can be found in products such as probiotics and food supplements. It has been shown to have beneficial effects on chronic viral hepatitis and may be used for treatment of bacterial translocation. Lactitol also inhibits pge2 production in mice with colitis, leading to decreased inflammatory responses in their small intestines and colon. This inhibition may also lead to suppression of tumor growth or promotion of apoptosis in colorectal cancer cells by inhibiting protein synthesis and cell division.br&gt;</p>

<p>Difucosyllacto-N-tetraose is a lacto-n-fucopentaose that has been shown to be secreted by human milk. The index of this oligosaccharide is not significantly different between breastfed and formula-fed infants, which indicates that it is not influenced by the type of infant feed. Difucosyllacto-N-tetraose can be used as a marker for the frequency of infections in neonates and infants, because its levels are decreased in cases of infection. This oligosaccharide is also related to the diversity of oligosaccharides in colostrum, as it is one component of a subset found only in colostrum samples from healthy mothers.</p>

<p>Ex algal/bacterial polysaccharides-value in b1-3 glucanase assays &amp; diagnostics</p>

<p>FA2B N-glycan also know as asialo, agalacto, core-fucosylated, bisected, bi-antennary N-linked glycan.</p>

<p>Lipopolysaccharide (LPS) is a molecule that is produced by Porphyromonas gingivalis. This molecule is also found in the outer membranes of Gram-negative bacteria and has been shown to have many effects on animal tissues. LPS activates HIF-1α, which leads to the production of inflammatory cytokines such as necrosis factor (TNF), and interferon regulatory factors (IRFs). These molecules signal for the production of more LPS. LPS also causes tissue growth and development by activating growth factors such as insulin-like growth factor 1. LPS also activates immune cells through signaling with chemokine receptors, promoting inflammation.</p>

<p>6-O-(a-D-[6,6'-2H2]Glucopyranosyl)-D-glucopyranose is a synthetic glycosylation product of 6,6'-dihydroxy-[1,1'-biphenyl]-2H-glycine and D-glucose. The compound is used for the synthesis of oligosaccharides and complex carbohydrates. This product is custom synthesized to meet specific needs and can be modified with methyl groups and fluorination. It has a high purity (≥98%) and CAS number.</p>

<p>Lactobionic acid ethyl ester is a custom synthesis of an oligosaccharide that is modified by fluorination, methylation, and click modification. Lactobionic acid ethyl ester is synthesized from the sugar D-glucose and the monosaccharide D-galactose. This product can be used as a substitute for sucrose in food products as it has similar taste, texture and sweetness. It also has many other applications such as being used in the manufacture of polysaccharides and complex carbohydrates.</p>

<p>LacDiNAc dimer ethylazide is a modified form of LacdiNAc that has been iodinated. It is synthesized by the reaction of two molecules of LacdiNAc with ethylazide. The product has an average molecular weight of 2,000 and is the most highly purified synthetic carbohydrate available. It can be used in a wide range of applications, including click chemistry, glycosylation reactions, and fluorination synthesis.</p>

<p>4-Aminobutyl 1,3-a-1,6-a-D-mannotriose is a custom synthesis that belongs to the category of oligosaccharides and polysaccharides. It is an aminotriose with a methyl group at the C4 position. The fluorinated glucose moiety and the 4-aminobutylic acid residue are in an alpha configuration. This oligosaccharide has been modified by click chemistry and features high purity. The modification was carried out by condensing the sugar with a boronic acid and then reacting this with an azide group. The resulting product is then reacted with a maleimide to create a conjugate that can be used in bioconjugation reactions.</p>

<p>Used to treat duodenal ulcers, GERD, stress ulcers; acid buffer; cytoprotective</p>

<p>GM1 pentasaccharide (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue (Ledeen, 2009). GM1 pentasaccahride is the carbohydrate moiety of GM1 ganglioside. GM1 ganglioside interacts and modulates tyrosine kinases, such a,s neural tropomyosin receptor kinase A (TrkA), by inducing the release of neurotrophins from fibroblast cells and the epidermal growth factor receptor (EGFR) (Higuero, 2009). GM1 ganglioside is also found in epithelial membranes; it is a key element for bacterial toxicity and viral infection as it acts as a receptor for the B-subunits of heat-labile toxin, cholera toxin, rotavirus, and simian virus 40. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>6'-N-Glycolylneuraminyl-D-lactose sodium salt is a custom synthesis that provides high purity and custom synthesis. It is a complex carbohydrate with a CAS number of 24932-91-0 and an Oligosaccharide, Monosaccharide, saccharide Carbohydrate. This product is Fluorination, Glycosylation, Synthetic, Methylation, Modification.</p>

<p>Raffinose-sp-biotin is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. It is available in CAS No. and has the molecular formula C6H14O6. Raffinose-sp-biotin is a polysaccharide with a complex carbohydrate structure.</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>2-Azidoethyl 2-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-mannopyranoside is a carbohydrate that is a modification of the saccharide oligosaccharide. It has been synthesized by custom synthesis and has high purity, methylation, glycosylation and click modification.</p>

<p>This is an oligosaccharide that has been modified with a fluorinated saccharide. It is a complex carbohydrate that has been synthesized through custom synthesis and is high purity with a CAS No. This monosaccharide has been methylated and glycosylated, and it can be used in the synthesis of polysaccharides.</p>

<p>1,4-b-D-Xylotetraose decasulfate sodium salt is a highly purified and custom synthesized carbohydrate. It is used as a reagent in biochemical research. 1,4-b-D-Xylotetraose decasulfate sodium salt can be modified with various reagents to produce desired properties for use in various applications. Modifications can include methylation, saccharide, Polysaccharide, Click modification, or Modification. Carbohydrate modifications can include Oligosaccharide or Custom synthesis. Fluorination of 1,4-b-D-Xylotetraose decasulfate sodium salt is an available modification that produces the product with high purity and reduced viscosity. <br>1,4-b-D-Xylotetraose decasulfate sodium salt has a CAS number of 52878-68-9 and is available for custom synthesis at</p>

<p>k-carrageenan derived tetrasaccharide alcohol disulfate+(3-6 anhydrogalactose)</p>

<p>N-Acetylneuraminyl-(a2-3)-D-galactopyranosyl-(b1-3)-D-N-acetylgalactosaminyl serine-biotin is a custom synthesis of complex carbohydrates. It is an oligosaccharide with a CAS number and has been modified with methylation, glycosylation, and click chemistry. The carbohydrate has a high purity and has been fluorinated for the purpose of making it synthetic.</p>